About 1,180 results

ALLMedicine™ Mycobacterium Abscessus Center

Research & Reviews  447 results

In Vitro Activity of Rifabutin against Mycobacterium abscessus, Including Clarithromyci...
Clinical and Experimental Pharmacology & Physiology; Chen J, Zhang H et. al.

May 10th, 2022 - The antibiotic options available for Mycobacterium abscessus (M. abscessus) infection are limited and no definitive therapeutic strategies have been formulated. The recent discovery that rifabutin is active against M. abscessus has raised interest...

Anti-Mycobacterium abscessus Activity of Tuberculosis F-ATP Synthase Inhibitor GaMF1.
Antimicrobial Agents and Chemotherapy; Ragunathan P, Dick T et. al.

Apr 29th, 2022 - New drug targets and molecules with bactericidal activity are needed against the respiratory mycobacterial pathogen Mycobacterium abscessus. Employing a lead repurposing strategy, the antituberculosis compound GaMF1 was tested against M. abscessus...

In Vitro Bedaquiline and Clofazimine Susceptibility Testing in Mycobacterium abscessus.
Antimicrobial Agents and Chemotherapy; Schulthess B, Akdoğan Kittana FN et. al.

Apr 15th, 2022 - Bedaquiline and clofazimine are increasingly used to treat infections with Mycobacterium abscessus. We determined distributions of MICs by broth microdilution for bedaquiline and clofazimine for 61 M. abscessus clinical isolates using different me...

Glby, Encoded by MAB_3167c, Is Required for In Vivo Growth of Mycobacteroides abscessus...
Journal of Bacteriology; Galanis C, Maggioncalda EC et. al.

Apr 6th, 2022 - Mycobacteroides abscessus (Mab; also known as Mycobacterium abscessus) is an emerging opportunistic pathogen. Patients with structural lung conditions such as bronchiectasis, cystic fibrosis, and chronic obstructive pulmonary disease are at high r...

Mycobacterium abscessus Scleral Buckle Infection.
Retinal Cases & Brief Reports; Cai S, Song A et. al.

Mar 29th, 2022 - To report the successful management of a rare case of Mycobacterium abscessus scleral buckle infection. Case report. A 63-year-old woman with a history of sarcoid anterior uveitis and macula-off retinal detachment repaired by scleral buckle and pa...

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Guidelines  2 results

Treatment of Nontuberculous Mycobacterial Pulmonary Disease: An Official ATS/ERS/ESCMID...
Clinical Infectious Diseases : an Official Publication Of... Daley CL, Iaccarino JM et. al.

Aug 17th, 2020 - Nontuberculous mycobacteria (NTM) represent over 190 species and subspecies, some of which can produce disease in humans of all ages and can affect both pulmonary and extrapulmonary sites. This guideline focuses on pulmonary disease in adults (wit...

Treatment of nontuberculous mycobacterial pulmonary disease: an official ATS/ERS/ESCMID...
The European Respiratory Journal; Daley CL, Iaccarino JM et. al.

Jul 9th, 2020 - Nontuberculous mycobacteria (NTM) represent over 190 species and subspecies, some of which can produce disease in humans of all ages and can affect both pulmonary and extrapulmonary sites. This guideline focuses on pulmonary disease in adults (wit...

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Clinicaltrials.gov  4 results

Phase II Study of a Nebulised Nitric Oxide Generating Solution in Patients With Cystic Fibrosis

Nov 1st, 2021 - Investigators will undertake an eighteen-week single centre, open label study in participants with cystic fibrosis infected with Mycobacterium abscessus (M. abscessus)-pulmonary disease (-PD). The study will treat particpants with cystic fibrosis ...

Trial of Inhaled Molgramostim in Cystic Fibrosis Subjects With Nontuberculous Mycobacterial Infection

Oct 27th, 2021 - A Screening period will begin up to 10 weeks prior to the Baseline visit for collection of the sputum sample, but the remainder of the assessments including Safety labs will be completed within 6 weeks of Baseline, to determine eligibility. Adult ...

Liposomal Amikacin for Inhalation (LAI) in the Treatment of Mycobacterium Abscessus Lung Disease

Mar 4th, 2020 - This is an open-label study of efficacy, safety and tolerability of once daily dosing of Liposomal-Amikacin for Inhalation (LAI), in addition to a standard multi-drug antibiotic therapy in accordance with the 2007 ATS/ IDSA guidelines, in patients...

The Role of Inflammasome in Inflammatory Macrophage in Mycobacterium Avium Complex-lung Disease and Mycobacterium Abscessus-lung Disease

Jun 30th, 2014 - Lung disease (LD) due to nontuberculous mycobacteria (NTM) becomes an important clinical concern, because the incidence and prevalence of NTM-LD have increased over the last decade. Among the NTM-LD in Taiwan, Mycobacterium avium complex (MAC) and...

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News  19 results

Immediate Treatment of M. Abscessus Urged for Cystic Fibrosis

May 11th, 2021 - NEW YORK (Reuters Health) - An analysis of whole genome data from cystic fibrosis patients reveals how multi-drug resistant pathogens evolve and suggests that Mycobacterium abscessus infection be treated promptly, contrary to current medical pract...

FDA Warns of Infection With Another Cooler–Heater Device

Oct 1st, 2020 - The US Food and Drug Administration (FDA) is warning once again about the potential risk for nontuberculosis mycobacteria (NTM) infection during cardiothoracic surgery using cooler–heater devices. In a letter to healthcare providers, the FDA says ...

Mycobacterium abscessus Infection Following Home Dermabrasion
Justin Grubbs, MD, Casey Bowen, MD

Jul 9th, 2019 - Case Report A 32-year-old woman presented to the dermatology clinic with a tender lump overlying the right maxilla of 6 weeks’ duration. The lesion developed acutely 1 to 2 months after the patient began using an at-home microdermabrasion device,.

Mycobacterium abscessus: A Rare Cause of Periprosthetic Knee Joint Infection

Sep 26th, 2018 - DISCUSSION Diagnosis of acute infection after TKA remains challenging, as some degree of pain, swelling, and even postoperative fevers may be common in noninfected TKA patients. Synovial white blood cell count and differential as well as alpha-def.

Mycobacteria subset plagues pulmonary patients
Heidi Splete, MDedge News

May 15th, 2017 - Nontuberculous mycobacteria accounts for an increasing percentage of pulmonary disease, and nonsurgical treatment alone has not shown effectiveness, according to data from a meta-analysis of 24 studies and 1,224 patients. The study results were pu.

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