About 20,665 results

ALLMedicine™ Mycobacterium Tuberculosis Center

Research & Reviews  7,854 results

The evolution of antibiotic resistance is associated with collateral drug phenotypes in...
Nature Communications; Waller NJE, Cheung CY et. al.

Mar 20th, 2023 - The increasing incidence of drug resistance in Mycobacterium tuberculosis has diminished the efficacy of almost all available antibiotics, complicating efforts to combat the spread of this global health burden. Alongside the development of new dru...

A mycobacterial effector promotes ferroptosis-dependent pathogenicity and dissemination.
Nature Communications; Qiang L, Zhang Y et. al.

Mar 19th, 2023 - Ferroptosis is a lipid peroxidation-driven and iron-dependent programmed cell death involved in multiple physical processes and various diseases. Emerging evidence suggests that several pathogens manipulate ferroptosis for their pathogenicity and ...

Ferroptosis hijacking by Mycobacterium tuberculosis.
Nature Communications; Gan B

Mar 19th, 2023 - Ferroptosis hijacking by Mycobacterium tuberculosis.|2023|Gan B,|

Ultrafast, One-Step, Label-Based Biosensor Diagnosis Platform for the Detection of Myco...
ACS Infectious Diseases; Yang X, Chen X et. al.

Mar 18th, 2023 - Tuberculosis (TB) is a chronic infectious disease caused by the etiological agent Mycobacterium tuberculosis (MTB). Because the majority of TB patients come from poor economic backgrounds, the development of a simple, specific, low-cost, and highl...

Factors associated with prevalent Mycobacterium tuberculosis infection and disease amon...
PloS One; Kim S, Hesseling AC et. al.

Mar 18th, 2023 - Understanding factors associated with prevalent Mycobacterium tuberculosis infection and prevalent TB disease in household contacts of patients with drug-resistant tuberculosis (TB) may be useful for TB program staff conducting contact investigati...

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Guidelines  8 results

Tuberculosis Screening, Testing, and Treatment of U.S. Health Care Personnel: Recommend...
MMWR. Morbidity and Mortality Weekly Report; Sosa LE, Njie GJ et. al.

May 18th, 2019 - The 2005 CDC guidelines for preventing Mycobacterium tuberculosis transmission in health care settings include recommendations for baseline tuberculosis (TB) screening of all U.S. health care personnel and annual testing for health care personnel ...

Recommendations for use of an isoniazid-rifapentine regimen with direct observation to ...
MMWR. Morbidity and Mortality Weekly Report;

Dec 14th, 2011 - Preventing tuberculosis (TB) by treating latent Mycobacterium tuberculosis infection (LTBI) is a cornerstone of the U.S. strategy for TB elimination. Three randomized controlled trials have shown that a new combination regimen of isoniazid (INH) a...

Drug-resistant tuberculosis: pediatric guidelines.
The Pediatric Infectious Disease Journal; Al-Dabbagh M, Lapphra K et. al.

Feb 8th, 2011 - Drug-resistant Mycobacterium tuberculosis (TB) infection represents a serious and growing problem. For patients infected or suspected of being infected with multidrug or extensively drug-resistant TB, several medications have to be given simultane...

Updated guidelines for using Interferon Gamma Release Assays to detect Mycobacterium tu...
MMWR. Recommendations and Reports : Morbidity and Mortali... Mazurek GH, Jereb J et. al.

Jun 26th, 2010 - n 2005, CDC published guidelines for using the QuantiFERON-TB Gold test (QFT-G) (Cellestis Limited, Carnegie, Victoria, Australia) (CDC. Guidelines for using the QuantiFERON-TB Gold test for detecting Mycobacterium tuberculosis infection, United S...

British Infection Society guidelines for the diagnosis and treatment of tuberculosis of...
The Journal of Infection; Thwaites G, Fisher M et. al.

Aug 1st, 2009 - SUMMARY AND KEY RECOMMENDATIONS: The aim of these guidelines is to describe a practical but evidence-based approach to the diagnosis and treatment of central nervous system tuberculosis in children and adults. We have presented guidance on tubercu...

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Drugs  11 results see all →

Clinicaltrials.gov  221 results

Training Protocol on the Natural History of Tuberculosis

Mar 17th, 2023 - Mycobacterium tuberculosis (MTB) is a slow-growing bacterium that establishes latent infection in millions of persons worldwide, but only leads to disease in 10% or less of these individuals. It typically causes pneumonia, however dissemination to...

Phase IV Clinical Study of Recombinant Mycobacterium Tuberculosis Fusion Protein

Mar 8th, 2023 - Assessment of effectiveness: In cohort 1, the injection site reaction was examined at 0min, 24h, 48h and 72h after skin test, and the transverse and longitudinal diameters of the erythema and induration were measured and recorded in millimeters (m...

Aerosol BCG Challenge Study in Historically BCG-vaccinated Volunteers

Mar 7th, 2023 - Tuberculosis (TB) remains one of the deadliest infectious disease killers worldwide. Key research priorities include the development of an effective vaccine. Currently, the only licensed vaccine against TB is the BCG (Bacille Calmette-Guérin). Thi...

Prevalence of Latent Tuberculosis Infection in Health-care Workers and Students

Mar 6th, 2023 - Mycobacterium tuberculosis may develop symptoms and signs of disease or may have no clinical evidence of disease (latent tuberculosis infection [LTBI]). TB disease remains one of the major causes of morbidity and mortality in the world. A survey t...

Coorticosteroid Regimen in Patients With Anti-PD-1/PD-L1 Induced Pneumonitis

Feb 23rd, 2023 - 1. Diagnostic period The screening for the study will involve patients with newly diagnosed interstitial changes in chest radiological examination or in patient with new respiratory system related symptoms. The radiological changes must be confirm...

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News  168 results

Multiple Annular Erythematous Plaques
Rachel Choi, MD, Jake Wang, MD et. al.

Dec 5th, 2022 - The Diagnosis: Mid-Borderline Multibacillary Leprosy The biopsies showed a granulomatous dermatitis involving the dermis and subcutaneous adipose tissue (Figure, A). Fite staining also revealed numerous acid-fast bacilli (AFB) throughout the dermi.

Most Global Bacterial Deaths in 2019 Linked to Five Pathogens

Nov 21st, 2022 - In what may be the first estimate of bacterial deaths worldwide, researchers reported 33 bacterial pathogens were responsible for more than 1 in 7 deaths in 2019, with five pathogens linked to slightly more than half of those deaths. "Deaths assoc...

Study Affirms Shorter Regimens for Drug-Resistant Tuberculosis

Nov 17th, 2022 - UPDATED November 18, 2022 // Editor's note: This article has been updated with additional comments. Two short-course bedaquiline-containing treatment regimens for rifampicin-resistant tuberculosis (TB) showed "robust evidence" for superior efficac...

Nothing Lasts Forever, Including Infant BCG Vaccine Protection

Aug 11th, 2022 - Infants who received BCG [bacille Calmette-Guérin] vaccination at birth had protection against tuberculosis into early childhood, but that protection largely disappeared in only a few years, according to a meta-analysis. Effectiveness of the BCG v...

RA: Real-world study highlights need for increased awareness of NTM in TNFi‐treated patients

Apr 26th, 2022 - Key clinical point: Patients with seropositive rheumatoid arthritis (RA) treated with tumor necrosis factor inhibitors (TNFi) were at higher risk of developing nontuberculous mycobacterium (NTM) infection in mycobacterium tuberculosis (MTB) endemi.

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Patient Education  4 results see all →