About 18,063 results

ALLMedicine™ Mycobacterium Tuberculosis Center

Research & Reviews  7,012 results

Verapamil regulates the macrophage immunity to Mycobacterium tuberculosis through NF-κB...
Current Molecular Medicine; Gong W, Cui R et. al.

May 17th, 2022 - Verapamil enhances the sensitivity of Mycobacterium tuberculosis to anti-tuberculosis (TB) drugs, promotes the macrophage anti-TB ability and reduces drug resistance, but its mechanism is unclear. Herein, we investigated the effect of Verapamil on...

CD39 pathway inhibits Th1 cell function in tuberculosis.
Immunology Luo Y, Xue Y et. al.

May 17th, 2022 - The role of CD39 pathway in Th1 cell function in tuberculosis (TB) is rarely elucidated. The present study aims to investigate the modulating mechanism of CD39 pathway during Mycobacterium tuberculosis (MTB) infection. CD39 expression was examined...

Role of an orphan substrate-binding protein MhuP in transient heme transfer in Mycobact...
International Journal of Biological Macromolecules; Mandal SK, Kanaujia SP

May 16th, 2022 - The redox property of iron makes it an essential cofactor for numerous enzymes involved in various metabolic processes. In vertebrates, iron is attached to either heme molecules or with other circulatory proteins, making its accessibility restrict...

Nanotechnology and tuberculosis: An old disease with new treatment strategies.
Tuberculosis (Edinburgh, Scotland); Macêdo DCDS, Cavalcanti IDL et. al.

May 15th, 2022 - Tuberculosis is an intracellular infectious disease caused by Mycobacterium tuberculosis, which mainly affects the lungs. Especially in patients infected by the Human Immunodeficiency Virus (HIV) or other immunosuppressed patients, tuberculosis is...

Intracellular Activity of Poly (DL-lactide-co-glycolide) Nanoparticles Encapsulated wit...
Current Drug Delivery; Jiang H, Li X et. al.

May 14th, 2022 - Multidrug-resistant Mycobacterium tuberculosis (MDR-TB) is a major cause of death amongst tuberculosis patients. Nanomedicine avoids some limitations of conventional drug treatment and increases therapeutic efficacy against bacterial infections. H...

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Guidelines  8 results

Tuberculosis Screening, Testing, and Treatment of U.S. Health Care Personnel: Recommend...
MMWR. Morbidity and Mortality Weekly Report; Sosa LE, Njie GJ et. al.

May 18th, 2019 - The 2005 CDC guidelines for preventing Mycobacterium tuberculosis transmission in health care settings include recommendations for baseline tuberculosis (TB) screening of all U.S. health care personnel and annual testing for health care personnel ...

Recommendations for use of an isoniazid-rifapentine regimen with direct observation to ...
MMWR. Morbidity and Mortality Weekly Report;

Dec 14th, 2011 - Preventing tuberculosis (TB) by treating latent Mycobacterium tuberculosis infection (LTBI) is a cornerstone of the U.S. strategy for TB elimination. Three randomized controlled trials have shown that a new combination regimen of isoniazid (INH) a...

Drug-resistant tuberculosis: pediatric guidelines.
The Pediatric Infectious Disease Journal; Al-Dabbagh M, Lapphra K et. al.

Feb 8th, 2011 - Drug-resistant Mycobacterium tuberculosis (TB) infection represents a serious and growing problem. For patients infected or suspected of being infected with multidrug or extensively drug-resistant TB, several medications have to be given simultane...

Updated guidelines for using Interferon Gamma Release Assays to detect Mycobacterium tu...
MMWR. Recommendations and Reports : Morbidity and Mortali... Mazurek GH, Jereb J et. al.

Jun 26th, 2010 - n 2005, CDC published guidelines for using the QuantiFERON-TB Gold test (QFT-G) (Cellestis Limited, Carnegie, Victoria, Australia) (CDC. Guidelines for using the QuantiFERON-TB Gold test for detecting Mycobacterium tuberculosis infection, United S...

British Infection Society guidelines for the diagnosis and treatment of tuberculosis of...
The Journal of Infection; Thwaites G, Fisher M et. al.

Aug 1st, 2009 - SUMMARY AND KEY RECOMMENDATIONS: The aim of these guidelines is to describe a practical but evidence-based approach to the diagnosis and treatment of central nervous system tuberculosis in children and adults. We have presented guidance on tubercu...

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Drugs  8 results see all →

Clinicaltrials.gov  72 results

The Influence of Malnutrition, Diabetes Mellitus, and Helminth Infections on Biosignatures in Latent Tuberculosis in a South Indian Population

May 13th, 2022 - Approximately 2 billion people worldwide are infected with Mycobacterium tuberculosis (TB), with 90% of individuals having latent infection (LTBI). The control of TB requires clearly delineated helper T cell (Th) 1 responses and, to a lesser exten...

Characterization of Tissue-Specific Immune Responses to Bronchoscopic Instillation of Mycobacterial Antigens Into the Human Lung

May 13th, 2022 - We propose a pilot study in which we employ directed bronchoscopic instillation of Mycobacterium tuberculosis (Mtb)-derived Purified Protein Derivative (PPD) to evaluate local airway immune response in adults with or without latent tuberculosis in...

Tuberculosis - Learning the Impact of Nutrition

May 6th, 2022 - The proposed work is based on the finding that one-third of the world is infected with the bacteria Mycobacterium tuberculosis (Mtb) and only 10% of these individuals develop TB. The study aims to identify factors that drive progression to disease...

Investigating Immune Responses to Aerosol BCG Challenge in Healthy UK Adults

Apr 22nd, 2022 - Mycobacterium tuberculosis (M.tb) is a pathogen with worldwide preponderance that infects humans and causes the transmissible disease tuberculosis (TB). An estimated one-third of the world's population is latently infected with M.tb, carrying a 10...

Effectiveness Of Mobile Application To Improve Adherence To Tuberculosis Treatment

Apr 21st, 2022 - Background Tuberculosis (TB) is an infectious disease that is caused by a bacterium called Mycobacterium tuberculosis. Worldwide, TB is considered as one of the major public health threats, where it is among the top ten causes of death and a leadi...

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News  123 results

RA: Real-world study highlights need for increased awareness of NTM in TNFi‐treated patients

Apr 26th, 2022 - Key clinical point: Patients with seropositive rheumatoid arthritis (RA) treated with tumor necrosis factor inhibitors (TNFi) were at higher risk of developing nontuberculous mycobacterium (NTM) infection in mycobacterium tuberculosis (MTB) endemi.

Innumerable pulmonary nodules
MDedge Family Medicine; Brian M. Fung, MD, Nasser Mikhail, MD et. al.

Mar 7th, 2022 - A 56-year-old woman with a history of a thyroid goiter following a partial thyroidectomy presented to the emergency department with shortness of breath, progressive weakness, and fatigue. She also reported a poor appetite and unintentional weight.

Vetiver: More Than a Pleasant Aroma?

Sep 30th, 2021 - An important ingredient in the contemporary perfume and cosmetics industries, vetiver, is the only grass cultivated throughout the world to retain its essential oil, which contains sesquiterpene alcohols and hydrocarbons.1-3 Field and glasshouse s...

Pediatric TB – more work needed, especially with HIV-coinfection
Caleb Rans, PharmD

Mar 9th, 2021 - Despite recent advances in the diagnosis, treatment, and prevention of pediatric tuberculosis in children living with HIV (CLHIV) and HIV-exposed uninfected children (HEU), several unmet needs remain, including studies evaluating the feasibility o.

Does Your Patient Have Latent TB Infection? Test Your Knowledge

Feb 12th, 2021 - More than 80% of tuberculosis (TB) cases in the United States are a result of untreated latent TB infection that progresses to TB disease. The Centers for Disease Control and Prevention (CDC) estimates that up to 13 million people in the United St...

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Patient Education  2 results see all →