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About 645 results

ALLMedicine™ Shigellosis Center

Research & Reviews  213 results

Shigellosis Cases with Bacterial Sexually Transmitted Infections: Population-Based Data...
https://doi.org/10.1097/OLQ.0000000000001641
Sexually Transmitted Diseases; Ridpath AD, Vanden Esschert KL et. al.

May 10th, 2022 - Shigella species, which cause acute diarrheal disease, are transmitted via fecal-oral and sexual contact. To better understand the overlapping populations affected by Shigella infections and sexually transmitted infections (STIs) in the United Sta...

Phase 2 Shigella Vaccine and Challenge
https://clinicaltrials.gov/ct2/show/NCT04242264

Apr 22nd, 2022 - This is a double-blind placebo-controlled trial to evaluate the safety, reactogenicity, immunogenicity and efficacy of a 10^6 cfu dose of an oral live-attenuated S. sonnei vaccine candidate, WRSs2, in up to 120 healthy males and non-pregnant femal...

Shigellosis
https://www.merckmanuals.com/en-ca/professional/infectious-diseases/gram-negative-bacilli/shigellosis

Apr 1st, 2022 - Shigellosis is an acute infection of the intestine caused by the gram-negative Shigella species. Symptoms include fever, nausea, vomiting, tenesmus, and diarrhea that is usually bloody. Diagnosis is clinical and confirmed by stool culture. Treatme...

Associations between ambient temperature and enteric infections by pathogen: a systemat...
https://doi.org/10.1016/S2542-5196(22)00003-1
The Lancet. Planetary Health; Chua PLC, Ng CFS et. al.

Mar 13th, 2022 - Numerous studies have quantified the associations between ambient temperature and enteric infections, particularly all-cause enteric infections. However, the temperature sensitivity of enteric infections might be pathogen dependent. Here, we sough...

Virulence genes expression profiling of different Shigella flexneri serotypes in respon...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8864791
Gut Pathogens; Sadredinamin M, Shabani M et. al.

Feb 24th, 2022 - Shigellosis is a self-limiting disease that antibiotic therapy could decrease its complications and duration. However, sublethal levels of antibiotics, may lead to alteration in disease state, besides its role in the emergence of resistant variant...

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Drugs  32 results see all →

Clinicaltrials.gov  3 results

Phase 2 Shigella Vaccine and Challenge
https://clinicaltrials.gov/ct2/show/NCT04242264

Apr 22nd, 2022 - This is a double-blind placebo-controlled trial to evaluate the safety, reactogenicity, immunogenicity and efficacy of a 10^6 cfu dose of an oral live-attenuated S. sonnei vaccine candidate, WRSs2, in up to 120 healthy males and non-pregnant femal...

Safety and Efficacy of the Bacteriophage Preparation, ShigActive™, in a Human Experimental Model of Shigellosis
https://clinicaltrials.gov/ct2/show/NCT05182749

Jan 18th, 2022 - The purpose of this study is to determine if ShigActive is safe and effective in healthy adults in a continuous Phase 1/2a trial. Phase 1 will asses the safety of ShigActive in healthy adults, while Phase 2a will evaluate the safety and efficacy o...

Shigella Sonnei OSPC-rDT Conjugate Vaccine
https://clinicaltrials.gov/ct2/show/NCT01399424

Jul 2nd, 2017 - The active ingredient of this Shigella sonnei O-SP-core conjugate vaccine is a saccharide-protein conjugate composed of a fragment of S. sonnei LPS. The saccharide component consists of an average of 3.5 repeat units of the O-SP plus the core regi...

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News  9 results

CDC Mandates Measles Quarantine for Afghanistan Evacuees
https://www.medscape.com/viewarticle/959222

Sep 22nd, 2021 - Evacuees of Afghanistan who have arrived in the United States must be vaccinated against measles and undergo quarantine for 21 days, according to a health advisory issued September 20 by the Centers for Disease Control and Prevention (CDC). At the...

Fast Five Quiz: How Much Do You Know About Common Conditions Associated With Diarrhea?
https://reference.medscape.com/viewarticle/900215_6

Aug 7th, 2018 - General supportive care of patients with shigellosis includes: Infection with Shigella is normally self-limited. The average duration of gastrointestinal symptoms of untreated shigellosis is 7 days Antibiotic treatment is indicated in some patient...

VIDEO: Infectious enteritis quadrupled short-term risk of IBS
https://www.mdedge.com/familymedicine/article/132135/infectious-diseases/video-infectious-enteritis-quadrupled-short-term
Internal Medicine News; Amy Karon

Feb 24th, 2017 - More than 10% of patients developed irritable bowel syndrome (IBS) within a year after infectious enteritis, which gave them a more than fourfold greater risk than that of controls, according to a systematic review and meta-analysis of 45 studies.

VIDEO: Infectious enteritis quadrupled short-term risk of IBS
https://www.mdedge.com/gihepnews/article/132135/infectious-diseases/video-infectious-enteritis-quadrupled-short-term-risk
Amy Karon, MDedge News

Feb 24th, 2017 - More than 10% of patients developed irritable bowel syndrome (IBS) within a year after infectious enteritis, which gave them a more than fourfold greater risk than that of controls, according to a systematic review and meta-analysis of 45 studies.

Morning Break: Ben Stiller's PSA; Black Box on HCV Drugs; Dr. Oz's Heart Attack Detector
https://www.medpagetoday.com/hematologyoncology/prostatecancer/60612

Oct 5th, 2016 - Actor Ben Stiller says a PSA test detected his prostate cancer and saved his life. "If he had followed the U.S. Preventive Services Task Force guidelines, I would have never gotten tested at all." (CNN) The FDA has issued a new warning about the c...

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Patient Education  1 results see all →