×
About 3,138 results

ALLMedicine™ Toxic Epidermal Necrolysis Center

Research & Reviews  884 results

Psychotherapeutic interventions for burns patients and the potential use with Stevens-J...
https://doi.org/10.1371/journal.pone.0270424
PloS One; O'Reilly P, Meskell P et. al.

Jun 28th, 2022 - The existing evidence demonstrates that survivors of SJS/TEN have reported long-lasting psychological effects of their condition. Burns patients experience similar psychological effects. It is important to look at ways to help allay the psychologi...

Postmarket Assessment for Drugs and Biologics Used in Dermatology and Cutaneous Adverse...
https://doi.org/10.1016/j.det.2022.02.002
Dermatologic Clinics; Reyes M, Kortepeter C et. al.

Jun 25th, 2022 - Postmarket surveillance is critical for the identification of rare safety risks, which are unlikely to be identified during clinical trials and the drug development program. Rare adverse drug reactions with the potential for serious outcomes, incl...

Toxic epidermal necrolysis-like acute graft-versus-host disease in pediatric bone marro...
https://doi.org/10.1111/pde.15069
Pediatric Dermatology; Sheu Song J, Huang JT et. al.

Jun 23rd, 2022 - Complications of hematopoietic stem cell transplant (HSCT) include acute graft-versus-host disease (aGVHD). Severe cutaneous aGVHD can present with generalized erythroderma, desquamation, and bullae which can mimic toxic epidermal necrolysis (TEN)...

Clinical features and outcomes in children with Stevens-Johnson syndrome and toxic epid...
https://doi.org/10.1111/1346-8138.16476
The Journal of Dermatology; Chi MH, Chung WH et. al.

Jun 19th, 2022 - Stevens-Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN) are life-threatening cutaneous conditions. However, studies of pediatric SJS/TEN are limited. To investigate the causes, clinical course, outcomes and complications of SJS and TEN...

Cutaneous manifestations following COVID-19 vaccination: A report of 25 cases.
https://doi.org/10.1111/dth.15651
Dermatologic Therapy; Shakoei S, Kalantari Y et. al.

Jun 19th, 2022 - Various adverse effects particularly cutaneous manifestations associated with different COVID-19 vaccines have been observed in practice. To evaluate all patients who presented to our tertiary center with skin manifestations following COVID-19 vac...

see more →

Guidelines  6 results

Society of Dermatology Hospitalists supportive care guidelines for the management of St...
https://doi.org/10.1016/j.jaad.2020.02.066
Journal of the American Academy of Dermatology; Seminario-Vidal L, Kroshinsky D et. al.

Mar 11th, 2020 - Stevens-Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN) are life-threatening conditions with high morbidity and mortality. Supportive care management of SJS/TEN is highly variable. A systematic review of the literature was performed by...

Outpatient management and follow-up recommendations for adverse drug reactions: guideli...
https://www.ncbi.nlm.nih.gov/pubmed/31233575
Cutis Khanna R, Vaudreuil A et. al.

Jun 25th, 2019 - Acute generalized exanthematous pustulosis (AGEP), drug rash with eosinophilia and systemic symptoms (DRESS) syndrome, and Stevens-Johnson syndrome (SJS)/toxic epidermal necrolysis (TEN) are types of adverse drug reactions (ADRs), each with their ...

British Association of Dermatologists' guidelines for the management of Stevens-Johnson...
https://doi.org/10.1111/bjd.17841
The British Journal of Dermatology; McPherson T, Exton LS et. al.

Mar 5th, 2019 - British Association of Dermatologists' guidelines for the management of Stevens-Johnson syndrome/toxic epidermal necrolysis in children and young people, 2018.|2019|McPherson T,Exton LS,Biswas S,Creamer D,Dziewulski P,|methods,standards,standards,...

Clinical Pharmacogenetics Implementation Consortium Guideline for HLA Genotype and Use ...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5847474
Clinical Pharmacology and Therapeutics; Phillips EJ, Sukasem C et. al.

Feb 3rd, 2018 - The variant allele HLA-B*15:02 is strongly associated with greater risk of Stevens-Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN) in patients treated with carbamazepine or oxcarbazepine. The variant allele HLA-A*31:01 is associated wi...

European Guidelines (S1) on the use of high-dose intravenous immunoglobulin in dermatol...
https://doi.org/10.1111/jdv.13725
Journal of the European Academy of Dermatology and Venere... Enk AH, Hadaschik EN et. al.

Oct 21st, 2016 - The treatment of severe dermatological autoimmune diseases and toxic epidermal necrolysis (TEN) with high-dose intravenous immunoglobulin (IVIg) is a well-established procedure in dermatology. As treatment with IVIg is usually considered for rare ...

see more →

Drugs  192 results see all →

Clinicaltrials.gov  25 results

Drug Reactions Sampling (COLLECTIONTOXIDERMIES)
https://clinicaltrials.gov/ct2/show/NCT03659227

May 3rd, 2022 - Intro: Dermatology department of Henri Mondor Hospital (Creteil, France), is a reference center for toxic bullous diseases and severe cutaneous drug reactions (Stevens-Johnson syndrome (SJS), Lyell syndrome (toxic epidermal necrolysis (TEN)), gene...

LYell SYndrome MEsenchymal Stromal Cells Treatment
https://clinicaltrials.gov/ct2/show/NCT04711200

May 3rd, 2022 - Stevens-Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN) are rare severe cutaneous adverse reactions (SCARs) to drugs. To date, no curative drug has demonstrated with a good level of evidence its ability to promote SJS and TEN healing a...

Nutritional and Metabolic Management of Toxidermia Patients Requiring Intensive Care (TEN Metabolism)
https://clinicaltrials.gov/ct2/show/NCT05320653

Apr 18th, 2022 - There are yet no description of the metabolic characteristics of patients admitted for Toxic epidermal necrolysis (TEN) or Stevens-Johnson Syndrome (SJS) which are a rare condition, often assimilated to major burns in terms of metabolic requiremen...

NATIENS: Optimal Management and Mechanisms of SJS/TEN
https://clinicaltrials.gov/ct2/show/NCT02987257

Apr 15th, 2022 - Background and Scientific Rationale Stevens-Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN), are severe, life-threatening immunologically mediated adverse drug reactions representing the same disease across a spectrum of severity that ...

Severe Bullous Drug Eruption and Filgrastim
https://clinicaltrials.gov/ct2/show/NCT04651439

Mar 16th, 2022 - Toxic epidermal necrolysis (TEN) including Stevens Johnson (SJS) and Lyell syndromes represent the most severe drug eruptions. It is an allergic disorder caused by cytotoxic T lymphocytes, specific of drugs, responsible for the destruction of kera...

see more →

News  146 results

Age, Skin Cancer Risks for ICI-Induced Bullous Pemphigoid
https://www.medscape.com/viewarticle/972516

Apr 21st, 2022 - Bullous pemphigoid, an immune-mediated condition chacterized by large, fluid-filled blisters on the skin, is a rare but serious complication of cancer therapy with immune checkpoint inhibitors (ICIs) that may result in treatment interruption or ce...

Blistering Lesions in a Newborn
https://www.mdedge.com/dermatology/article/253884/pediatrics/blistering-lesions-newborn
Gabriella Alvarez, BS, Shivani Shah, DO, MPH et. al.

Apr 19th, 2022 - The Diagnosis: Epidermolysis Bullosa Our patient was found to have epidermolysis bullosa (EB), a rare genetic disease in which the superficial layers of the skin separate to form vesicles or bullae due to a mutation in the keratin 14 gene, KRT14.

Adverse Skin Effects of Cancer Immunotherapy Reviewed
https://www.medscape.com/viewarticle/970581

Mar 18th, 2022 - Immune checkpoint inhibitors (ICIs) have unquestionably revolutionized the care of patients with malignant melanoma, non-small cell lung cancer, and other types of cancer. But about 40% of patients with cancer treated with ICIs will experience imm...

Graft-vs-host Disease and Toxic Epidermal Necrolysis Following Hematopoietic Stem Cell Transplantation
https://www.mdedge.com/dermatology/article/251727/dermatopathology/graft-vs-host-disease-and-toxic-epidermal-necrolysis
Nora Vera, MD, Suzanna Lewis, MD et. al.

Feb 14th, 2022 - To the Editor: Acute graft-vs-host disease (GVHD) remains a limitation to hematopoietic stem cell transplantation (HSCT) in 20% to 50% of patients after transplant. Furthermore, failed treatment with corticosteroids is frequent and portends a poor.

Blisters in a Comatose Elderly Woman
https://www.mdedge.com/dermatology/article/250850/dermatopathology/blisters-comatose-elderly-woman
David J. Kurtyka, MD, Karl M. Saardi, MD et. al.

Jan 19th, 2022 - The Diagnosis: Coma Blisters Histologic examination revealed pauci-inflammatory subepidermal blisters with swelling of eccrine cells, signaling impending gland necrosis (Figure). Direct immunofluorescence testing on perilesional skin was negative.

see more →

Patient Education  2 results see all →