ALLMedicine™ Acute Erythroid Leukemia Center
Research & Reviews 75 results
https://doi.org/10.1182/blood.2020010544
Blood Zhang JP, Cheng T
Mar 25th, 2021 - Modeling acute erythroid leukemia via CRISPR.|2021|Zhang JP,Cheng T,|
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7995291
Blood Iacobucci I, Qu C et. al.
Jan 29th, 2021 - Acute erythroid leukemia (AEL) is characterized by a distinct morphology, mutational spectrum, lack of preclinical models, and poor prognosis. Here, using multiplexed genome editing of mouse hematopoietic stem and progenitor cells and transplant a...
https://doi.org/10.2174/1566524021666210121142316
Current Molecular Medicine; Liao Z, Li J et. al.
Jan 21st, 2021 - Acute erythroid leukemia (AEL) is a subtype of acute myeloid leukemia (AML) with features such as accumulation of maturation-arrested erythroblasts. Compared with AML, the progression of AEL is faster and the prognosis to available therapy is wors...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7724911
Blood Advances; Chisholm KM, Heerema-McKenney AE et. al.
Dec 7th, 2020 - Acute erythroid leukemia (AEL) is a rare subtype of acute myeloid leukemia (AML) primarily affecting older adults and was previously classified into erythroid/myeloid and pure erythroid subtypes. In this pediatric AEL study, we evaluated morpholog...
https://doi.org/10.1038/s41375-020-01075-3
Leukemia Sportoletti P, Sorcini D et. al.
Nov 7th, 2020 - Recurrent loss-of-function mutations of BCL6 co-repressor (BCOR) gene are found in about 4% of AML patients with normal karyotype and are associated with DNMT3a mutations and poor prognosis. Therefore, new anti-leukemia treatments and mouse models...
Clinicaltrials.gov 75 results
https://doi.org/10.1182/blood.2020010544
Blood Zhang JP, Cheng T
Mar 25th, 2021 - Modeling acute erythroid leukemia via CRISPR.|2021|Zhang JP,Cheng T,|
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7995291
Blood Iacobucci I, Qu C et. al.
Jan 29th, 2021 - Acute erythroid leukemia (AEL) is characterized by a distinct morphology, mutational spectrum, lack of preclinical models, and poor prognosis. Here, using multiplexed genome editing of mouse hematopoietic stem and progenitor cells and transplant a...
https://doi.org/10.2174/1566524021666210121142316
Current Molecular Medicine; Liao Z, Li J et. al.
Jan 21st, 2021 - Acute erythroid leukemia (AEL) is a subtype of acute myeloid leukemia (AML) with features such as accumulation of maturation-arrested erythroblasts. Compared with AML, the progression of AEL is faster and the prognosis to available therapy is wors...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7724911
Blood Advances; Chisholm KM, Heerema-McKenney AE et. al.
Dec 7th, 2020 - Acute erythroid leukemia (AEL) is a rare subtype of acute myeloid leukemia (AML) primarily affecting older adults and was previously classified into erythroid/myeloid and pure erythroid subtypes. In this pediatric AEL study, we evaluated morpholog...
https://doi.org/10.1038/s41375-020-01075-3
Leukemia Sportoletti P, Sorcini D et. al.
Nov 7th, 2020 - Recurrent loss-of-function mutations of BCL6 co-repressor (BCOR) gene are found in about 4% of AML patients with normal karyotype and are associated with DNMT3a mutations and poor prognosis. Therefore, new anti-leukemia treatments and mouse models...