About 60 results

ALLMedicine™ Acute Myelomonocytic Leukemia Center

Research & Reviews  23 results

Clinical and Molecular Approach to Adult-Onset, Neoplastic Monocytosis.
Current Hematologic Malignancy Reports; Shallis RM, Siddon AJ et. al.

Apr 24th, 2021 - In this review, we provide a comprehensive and contemporary understanding of malignant monocytosis and provide a framework by which the appropriate diagnosis with malignant monocytosis can be rendered. Increasing data support the use of molecular ...

Pure erythroid leukemia subsequent to acute myelomonocytic leukemia: A case report.
Medicine Ji J, Li Y et. al.

Apr 14th, 2021 - Pure erythroid leukemia is a rare subcategory of acute myeloid leukemia characterized by predominant immature erythroid population. Its occurrence subsequent to acute myelomonocytic leukemia has not been reported before. We reported this rare case...

LILRB4-targeting Antibody-Drug Conjugates for the Treatment of Acute Myeloid Leukemia.
Molecular Cancer Therapeutics; Anami Y, Deng M et. al.

Sep 4th, 2020 - Acute myeloid leukemia (AML) is the most common and aggressive blood cancer in adults. In particular, significant unmet medical needs exist for effective treatment strategies for acute myelomonocytic leukemia (M4) and acute monocytic leukemia (M5)...

Targeting Membrane HDM-2 by PNC-27 Induces Necrosis in Leukemia Cells But Not in Normal...
Anticancer Research; Thadi A, Lewis L et. al.

Sep 4th, 2020 - Anticancer peptide PNC-27 binds to HDM-2 protein on cancer cell membranes inducing the formation of cytotoxic transmembrane pores. Herein, we investigated HDM-2 membrane expression and the effect of PNC-27 treatment on human non-stem cell acute my...

Pathology of Acute Myeloid Leukemia Not Otherwise Specified (AML NOS) 

Jul 21st, 2020 - In the 2016 update to the 2008 World Health Organization (WHO) classification system,[1, 2]  the category "acute myeloid leukemia [AML] not otherwise specified" [NOS])" excludes AML subtypes associated with recurrent genetic abnormalities such as:...

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News  1 results

Outcomes worse with secondary and therapy-related AML compared with de novo AML
Jennifer Kelly Shepphird

Aug 24th, 2015 - Clinical outcomes were significantly worse among younger patients with secondary and therapy-related acute myeloid leukemia (sAML and tAML, respectively) compared with de novo disease, suggesting the presence of distinct AML subtypes, in a study p.

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