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About 320 results

ALLMedicine™ Afibrinogenemia Center

Research & Reviews  157 results

Clinical phenotype, fibrinogen supplementation and health-related quality of life in pa...
https://doi.org/10.1182/blood.2020009472
Blood Casini A, von Mackensen S et. al.

Jan 29th, 2021 - Due to its low prevalence, epidemiologic data on afibrinogenemia are limited and none are available on health-related quality of life (HRQoL). We conducted a cross-sectional international study to characterize the clinical features, the fibrinogen...

Pharmacokinetics, surrogate efficacy and safety evaluations of a new human plasma-deriv...
https://doi.org/10.1016/j.thromres.2020.12.026
Thrombosis Research; Ross CR, Subramanian S et. al.

Jan 24th, 2021 - Congenital afibrinogenemia is a rare coagulation disorder resulting from a deficiency in fibrinogen. This study assessed the pharmacokinetics, surrogate efficacy and safety of FIB Grifols, a new human plasma-derived fibrinogen concentrate, to trea...

Heterogeneity of congenital afibrinogenemia, from epidemiology to clinical consequences...
https://doi.org/10.1016/j.blre.2020.100793
Blood Reviews; Casini A, Neerman-Arbez M et. al.

Jan 9th, 2021 - Fibrinogen is a complex protein playing a major role in coagulation. Congenital afibrinogenemia, characterized by the complete absence of fibrinogen, is associated with major hemostatic defects. Even though the clinical course is unpredictable and...

Afibrinogenemia caused by a novel homozygous missense mutation, FGB p.Cys241Tyr, in a m...
https://doi.org/10.1111/hae.14211
Haemophilia : the Official Journal of the World Federatio... Zdziarska J, Wypasek E et. al.

Nov 27th, 2020 - Congenital afibrinogenemia is a severe bleeding disorder, sometimes manifesting as thrombosis and/or pregnancy complications. Intracranial haemorrhage (ICH) constitutes the major cause of death in this disease. We present the case of a male patien...

Screening method for congenital dysfibrinogenemia using clot waveform analysis with the...
https://doi.org/10.1111/ijlh.13358
International Journal of Laboratory Hematology; Arai S, Kamijo T et. al.

Oct 8th, 2020 - Congenital fibrinogen disorders (CFDs) are classified as afibrinogenemia or hypofibrinogenemia (Hypo), dysfibrinogenemia (Dys), or hypodysfibrinogenemia (Hypodys), according to functional and antigenic fibrinogen concentrations. However, in routin...

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Drugs  2 results see all →

Clinicaltrials.gov  161 results

Clinical phenotype, fibrinogen supplementation and health-related quality of life in pa...
https://doi.org/10.1182/blood.2020009472
Blood Casini A, von Mackensen S et. al.

Jan 29th, 2021 - Due to its low prevalence, epidemiologic data on afibrinogenemia are limited and none are available on health-related quality of life (HRQoL). We conducted a cross-sectional international study to characterize the clinical features, the fibrinogen...

Pharmacokinetics, surrogate efficacy and safety evaluations of a new human plasma-deriv...
https://doi.org/10.1016/j.thromres.2020.12.026
Thrombosis Research; Ross CR, Subramanian S et. al.

Jan 24th, 2021 - Congenital afibrinogenemia is a rare coagulation disorder resulting from a deficiency in fibrinogen. This study assessed the pharmacokinetics, surrogate efficacy and safety of FIB Grifols, a new human plasma-derived fibrinogen concentrate, to trea...

Heterogeneity of congenital afibrinogenemia, from epidemiology to clinical consequences...
https://doi.org/10.1016/j.blre.2020.100793
Blood Reviews; Casini A, Neerman-Arbez M et. al.

Jan 9th, 2021 - Fibrinogen is a complex protein playing a major role in coagulation. Congenital afibrinogenemia, characterized by the complete absence of fibrinogen, is associated with major hemostatic defects. Even though the clinical course is unpredictable and...

Fibryga - fibrinogen (human) kit-Octapharma USA Inc
https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=007a93f4-d84b-1fa9-51ed-32f6140bf423

Dec 21st, 2020 - FIBRYGA is a human fibrinogen concentrate indicated for the treatment of acute bleeding episodes in adults and children with congenital fibrinogen deficiency, including afibrinogenemia and hypofibrinogenemia. FIBRYGA is not indicated for dysfibrin...

Afibrinogenemia caused by a novel homozygous missense mutation, FGB p.Cys241Tyr, in a m...
https://doi.org/10.1111/hae.14211
Haemophilia : the Official Journal of the World Federatio... Zdziarska J, Wypasek E et. al.

Nov 27th, 2020 - Congenital afibrinogenemia is a severe bleeding disorder, sometimes manifesting as thrombosis and/or pregnancy complications. Intracranial haemorrhage (ICH) constitutes the major cause of death in this disease. We present the case of a male patien...

see more →