ALLMedicine™ Aplastic Anemia Center
Research & Reviews 1,031 results
Drug and Chemical Toxicology; Salimi A, Khodaparast F et. al.
Jul 27th, 2021 - Benzene exposure results in bone marrow suppression, leading to a decrease in the number of circulating white blood cells, an increased risk of chronic lymphocytic leukemia, acute myeloid leukemia and aplastic anemia. Since the mechanism of induct...
https://doi.org/10.1007/s00277-021-04553-5 10.1182/asheducation-2013.1.76 10.1182/blood-2016-08-693481 10.1007/s00277-015-2348-5 10.1111/j.0902-4441.2005.t01-1-EJH2467.x 10.1111/bjh.14790 10.1111/bjh.12656 10.3324/haematol.2019.216374 10.1007/s40265-019-01159-0 10.1038/s41375-021-01190-9 10.1038/nrdp.2017.28 10.1182/blood-2004-04-1472 10.1080/10428190600555520 10.1182/blood-2016-09-740845 10.1016/j.exphem.2013.01.001 10.1016/j.exphem.2014.12.002 10.1182/blood-2003-11-3959 10.1111/j.1365-2141.1989.tb06289.x 10.1097/MPH.0b013e31822bf699 10.3324/haematol.11359 10.1002/pbc.21143 10.3760/cma.j.issn.0253-2727.2016.05.009 10.1371/journal.pone.0098142 10.1182/blood.V184.108.40.206 10.1111/bjh.14862 10.3760/cma.j.issn.0253-2727.2016.04.016
Annals of Hematology; Yang W, Zhao X et. al.
Jul 17th, 2021 - The presence of paroxysmal nocturnal hemoglobinuria (PNH) clones in aplastic anemia (AA) suggests immunopathogenesis, but when and how PNH clones emerge and proliferate are unclear. Hepatitis-associated aplastic anemia (HAAA) is a special variant ...
https://doi.org/10.1007/s00277-021-04566-0 10.3324/haematol.2008.002642 10.1182/blood.V75.8.1646.1646 10.3324/haematol.12020 10.1111/j.1651-2227.1996.tb13938.x 10.3324/haematol.2017.169862 10.1007/bf03165112 10.1007/s00277-018-3486-3 10.1182/blood-2005-01-0161 10.3324/haematol.12855 10.1111/bjh.13853 10.1016/j.bbmt.2010.10.028 10.1007/s12185-016-2053-8 10.1007/s12185-018-02583-w 10.1002/ajh.25081 10.1111/j.1365-2141.2009.07842.x 10.3389/fonc.2018.00587 10.1016/j.hoc.2018.03.001 10.1159/000499065 10.1182/blood-2016-01-636381 10.1111/bjh.14510 10.1007/s00277-010-0944-y 10.1182/blood-2008-09-178871 10.1007/BF03345745 10.1080/10245332.2018.1435045 10.1002/ajh.21118 10.1182/blood.V220.127.116.11 10.1111/j.1365-2141.1993.tb04645.x 10.1177/147323001103900546
Annals of Hematology; Norasetthada L, Wongkhantee S et. al.
Jul 17th, 2021 - The incidence and outcomes of aplastic anemia (AA) in Asia remain limited. This study aimed to explore the incidence and outcomes of patients with adult AA across the country of Thailand. This is a prospective multi-center nationwide population-ba...
Pediatric Transplantation; Gonzalez-Villarreal G, Pequeño-Luevano M et. al.
Jul 14th, 2021 - The only curative treatment for severe aplastic anemia in children is an allogeneic stem cell transplant; however, few patients have a matched related or unrelated donor. Haploidentical stem cell transplantation (haplo-SCT) using bone marrow (BM) ...
https://doi.org/10.1038/s41409-021-01400-z 10.1016/S0140-6736(72)90292-9 10.1182/blood.V84.3.941.941 10.1097/00007890-197604000-00005 10.1182/blood-2003-07-2546 10.1200/JCO.2010.33.7212 10.1182/bloodadvances.2019000722 10.1056/NEJM199703273361301 10.1182/blood.V87.1.386.386 10.1056/NEJM199310143291603 10.1200/JCO.2005.02.7052 10.1001/jamadermatol.2015.121 10.1001/jamadermatol.2020.0559 10.1182/blood-2003-06-2145 10.1001/jamaoncol.2018.4934 10.1182/blood-2004-09-3411 10.1182/blood-2007-07-099283 10.1038/s41375-018-0218-6 10.1182/blood-2015-03-631747
Bone Marrow Transplantation; Socié G, Peffault de Latour R
Jul 9th, 2021 - Secondary malignancies after transplantation for aplastic anemia.|2021|Socié G,Peffault de Latour R,|
Guidelines 1 results
Haematologica Bennett JM, Orazi A
Jan 16th, 2009 - Members of the French-American-British Cooperative Leukemia Working Group met to review cases of aplastic anemia, hypocellular myelodysplastic syndrome and hypocellular acute myeloid leukemia. Criteria were proposed and modified following three wo...
Drugs 142 results see all →
Clinicaltrials.gov 110 results
May 7th, 2020 - The purpose of this protocol is to collect blood (ages 8 and older), bone marrow (ages 18 and older), skin tissue samples (ages 18 and older), and/or buccal mucosa samples (ages 8 and older) from healthy volunteers. Samples will be used for clinic...
Apr 30th, 2020 - Severe aplastic anemia (SAA) is a life-threatening bone marrow failure disorder characterized by pancytopenia and a hypocellular bone marrow. Allogeneic bone marrow transplantation and immunosuppressive treatment with anti-thymocyte globulin (ATG)...
Apr 29th, 2020 - Our laboratory has a long-standing interest in viruses that affect the bone marrow, especially those causing bone marrow failure. One specific syndrome, hepatitis-associated aplastic anemia, suggests that the same agent is responsible for the seve...
Apr 27th, 2020 - Fanconi anemia (FA) is a rare genetic disease that often presents as a bone marrow failure (BMF) syndrome but also can affect any other organ. Etiologically, loss of function mutations in more than 21 different gene members of the FA core complex ...
Apr 24th, 2020 - Severe acquired aplastic anemia (SAA) has a poor prognosis if untreated. Bone marrow transplantation is available to only a minority of patients due to lack of a matched sibling donor, advanced age of the patient, or cost. Clinical studies at NIH ...
News 56 results
Mark S. Lesney
Mar 6th, 2020 - Inferior overall survival was observed in patients with aplastic anemia who had mixed or complete recipient-type chimerism or complete donor chimerism after hematopoietic stem cell transplantation (HSCT), according to the results of a registry dat.
Oct 7th, 2019 - Treatment of Acquired Aplastic Anemia Supportive Care While the workup and treatment plan are being established, attention should be directed at supportive care for prevention of complications. The most common complications leading to death in pat.
Dominick A, Fields-Meehan JE et. al.
Sep 5th, 2019 - Background: Dual immune checkpoint blockade (DICB) is utilized for a variety of malignancies. These therapies have a unique and often unpredictable side effect profile compared to conventional chemotherapy.
Jan 23rd, 2019 - Immunosuppressive Therapy For patients without an HLA-matched sibling donor or those who are older than 50 years of age, immunosuppressive therapy is the first-line therapy. ATG and cyclosporine A are the treatments of choice.
Jan 18th, 2019 - In addition to peripheral blood findings, bone marrow biopsy is essential for the diagnosis, and should demonstrate a markedly hypocellular marrow (cellularity < 25%), occasionally with an increase in T lymphocytes. 7,39 Because marrow cellularity.