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About 451 results

ALLMedicine™ Factor XI Deficiency Center

Research & Reviews  225 results

A novel mutation (Leu60Pro) in a Chinese pedigree with hereditary factor XI deficiency.
https://doi.org/10.1097/MBC.0000000000001010
Blood Coagulation & Fibrinolysis : an International Journ... Xie H, Liu M et. al.

Jan 14th, 2021 - To analyse F11 gene mutations in a Chinese pedigree with hereditary factor XI (FXI) deficiency and investigate the molecular mechanism. The plasma FXI activity and FXI antigen of the proband and the family members were detected by clotting assay a...

Factor XI Deficiency in a Patient with Cervical Spondylotic Myelopathy.
https://doi.org/10.1097/BRS.0000000000003805
Spine Serikyaku H, Higa S et. al.

Nov 12th, 2020 - Case report. To summarize the clinical manifestations and treatment of Factor XI deficiency in a patient with cervical spondylotic myelopathy. Factor XI deficiency is a rare genetic bleeding disorder caused by reduced levels and insufficient activ...

Turning Up to Eleven: Factor XI Inhibitors as Novel Agents to Maximize Safety and Maint...
https://doi.org/10.1016/j.cpcardiol.2020.100696
Current Problems in Cardiology; Cave BE, Shah SP

Sep 30th, 2020 - Within the past decade nonvitamin K oral anticoagulants have emerged as the standard of care for the prevention and treatment of thromboembolic disorders, however safety of anticoagulants remain a concern for many patients and providers. There exi...

Tissue Factor-Independent Coagulation Correlates with Clinical Phenotype in Factor XI D...
https://doi.org/10.1055/s-0040-1715899
Thrombosis and Haemostasis; Bertaggia Calderara D, Zermatten MG et. al.

Sep 13th, 2020 - In factor XI (FXI) deficiency, bleeding cannot be predicted by routine analyses. Since FXI is involved in tissue factor (TF)-independent propagation loop of coagulation, we hypothesized that investigating the spatiotemporal separated phases of coa...

First case of delayed traumatic intracerebral hemorrhage in a patient with undiagnosed ...
https://doi.org/10.1080/02699052.2020.1807057
Brain Injury; Espinosa-Rodríguez EE, López-Gutiérrez M et. al.

Aug 20th, 2020 - Factor XI (FXI) deficiency, also known as hemophilia C, is included in the rare bleeding disorders (RBDs). It is distinct from other coagulation factor deficiencies because it rarely presents as spontaneous hemorrhage, but rather as bleeding after...

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Clinicaltrials.gov  225 results

A novel mutation (Leu60Pro) in a Chinese pedigree with hereditary factor XI deficiency.
https://doi.org/10.1097/MBC.0000000000001010
Blood Coagulation & Fibrinolysis : an International Journ... Xie H, Liu M et. al.

Jan 14th, 2021 - To analyse F11 gene mutations in a Chinese pedigree with hereditary factor XI (FXI) deficiency and investigate the molecular mechanism. The plasma FXI activity and FXI antigen of the proband and the family members were detected by clotting assay a...

Factor XI Deficiency in a Patient with Cervical Spondylotic Myelopathy.
https://doi.org/10.1097/BRS.0000000000003805
Spine Serikyaku H, Higa S et. al.

Nov 12th, 2020 - Case report. To summarize the clinical manifestations and treatment of Factor XI deficiency in a patient with cervical spondylotic myelopathy. Factor XI deficiency is a rare genetic bleeding disorder caused by reduced levels and insufficient activ...

Turning Up to Eleven: Factor XI Inhibitors as Novel Agents to Maximize Safety and Maint...
https://doi.org/10.1016/j.cpcardiol.2020.100696
Current Problems in Cardiology; Cave BE, Shah SP

Sep 30th, 2020 - Within the past decade nonvitamin K oral anticoagulants have emerged as the standard of care for the prevention and treatment of thromboembolic disorders, however safety of anticoagulants remain a concern for many patients and providers. There exi...

Tissue Factor-Independent Coagulation Correlates with Clinical Phenotype in Factor XI D...
https://doi.org/10.1055/s-0040-1715899
Thrombosis and Haemostasis; Bertaggia Calderara D, Zermatten MG et. al.

Sep 13th, 2020 - In factor XI (FXI) deficiency, bleeding cannot be predicted by routine analyses. Since FXI is involved in tissue factor (TF)-independent propagation loop of coagulation, we hypothesized that investigating the spatiotemporal separated phases of coa...

First case of delayed traumatic intracerebral hemorrhage in a patient with undiagnosed ...
https://doi.org/10.1080/02699052.2020.1807057
Brain Injury; Espinosa-Rodríguez EE, López-Gutiérrez M et. al.

Aug 20th, 2020 - Factor XI (FXI) deficiency, also known as hemophilia C, is included in the rare bleeding disorders (RBDs). It is distinct from other coagulation factor deficiencies because it rarely presents as spontaneous hemorrhage, but rather as bleeding after...

see more →

News  1 results

FDA clears direct-to-consumer marketing of genetic risk tests
https://www.mdedge.com/hematology-oncology/article/185766/anemia/fda-clears-direct-consumer-marketing-genetic-risk-tests
HT Staff

Apr 7th, 2017 - Image by Spencer Phillips DNA helix The US Food and Drug Administration (FDA) has authorized marketing of 23andMe Personal Genome Service (PGS) Genetic Health Risk (GHR) tests for 10 medical conditions. These are the first direct-to-consumer tests.

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