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About 4,845 results

ALLMedicine™ Hemolytic Uremic Syndrome Center

Research & Reviews  2,339 results

The molecular bases for the association of FHR-1 with atypical hemolytic uremic syndrom...
https://doi.org/10.1182/blood.2020010069
Blood Martin Merinero H, Subías M et. al.

Mar 2nd, 2021 - Factor H-related proteins (FHRs) are a group of partly characterized complement proteins that are thought to promote complement activation by competing binding of factor H (FH) to surface-bound C3b. Among them, FHR-1 is remarkable because is assoc...

Extracellular Vesicles and Renal Endothelial Cells: a Fatal Attraction in Hemolytic Ure...
https://doi.org/10.1016/j.ajpath.2021.02.011
The American Journal of Pathology; Varrone E, Carnicelli D et. al.

Mar 2nd, 2021 - This review will focus on typical hemolytic uremic syndrome (HUS), a life-threatening sequela of human infections caused, particularly in children, by Shiga toxin-producing Escherichia coli strains (STEC). Thrombotic microangiopathy of the brain a...

Serum insulin-like growth factor-binding protein 2 levels as an indicator for disease s...
https://doi.org/10.1080/0886022X.2021.1885445
Renal Failure; Tasaki Y, Inoue N et. al.

Mar 1st, 2021 - Insulin-like growth factor-binding protein (IGFBP) 2 plays an important role in the regulation of cell adhesion, migration, growth, and apoptosis. This study aimed to investigate the clinical significance of serum IGFBP2 as a biomarker for disease...

50 Years Ago in TheJournalofPediatrics: Therapy of Hemolytic Uremic Syndrome, a 50-Year...
https://doi.org/10.1016/j.jpeds.2020.11.039
The Journal of Pediatrics; Salinas Silva CA, Ortega Alonzo SE

Feb 26th, 2021 - 50 Years Ago in TheJournalofPediatrics: Therapy of Hemolytic Uremic Syndrome, a 50-Year Update.|2021|Salinas Silva CA,Ortega Alonzo SE,|

Genomic Characterization of hlyF-positive Shiga Toxin-Producing Escherichia coli, Italy...
https://doi.org/10.3201/eid2703.203110
Emerging Infectious Diseases; Gigliucci F, van Hoek AHAM et. al.

Feb 24th, 2021 - Shiga toxin-producing Escherichia coli (STEC) O80:H2 has emerged in Europe as a cause of hemolytic uremic syndrome associated with bacteremia. STEC O80:H2 harbors the mosaic plasmid pR444_A, which combines several virulence genes, including hlyF a...

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Guidelines  9 results

Outbreak of E. coli Infections
https://www.cdc.gov/ecoli/2019/o103-04-19/index.html

Apr 4th, 2019 - As of April 4, 2019, 72 people infected with the outbreak strain of E. coli O103 have been reported from five states. Eight people have been hospitalized. No cases of hemolytic uremic syndrome (HUS) or deaths have been reported.

Clinical guides for atypical hemolytic uremic syndrome in Japan.
https://doi.org/10.1007/s10157-016-1276-6
Clinical and Experimental Nephrology; Kato H, Nangaku M et. al.

Jul 16th, 2016 - Atypical hemolytic uremic syndrome (aHUS) is a rare disease characterized by the triad of microangiopathic hemolytic anemia, thrombocytopenia, and acute kidney injury. In 2013, we developed diagnostic criteria to enable early diagnosis and timely ...

An international consensus approach to the management of atypical hemolytic uremic synd...
https://doi.org/10.1007/s00467-015-3076-8
Pediatric Nephrology (Berlin, Germany); Loirat C, Fakhouri F et. al.

Apr 10th, 2015 - Atypical hemolytic uremic syndrome (aHUS) emerged during the last decade as a disease largely of complement dysregulation. This advance facilitated the development of novel, rational treatment options targeting terminal complement activation, e.g....

Guidelines for the management and investigation of hemolytic uremic syndrome.
https://doi.org/10.1007/s10157-014-0995-9
Clinical and Experimental Nephrology; Igarashi T, Ito S et. al.

Aug 7th, 2014 - Guidelines for the management and investigation of hemolytic uremic syndrome.|2014|Igarashi T,Ito S,Sako M,Saitoh A,Hataya H,|standards,diagnosis,etiology,therapy,standards,

Diagnostic criteria for atypical hemolytic uremic syndrome proposed by the Joint Commit...
https://doi.org/10.1007/s10157-013-0911-8
Clinical and Experimental Nephrology; Sawai T, Nangaku M et. al.

Dec 17th, 2013 - Atypical hemolytic uremic syndrome (aHUS) is rare and comprises the triad of microangiopathic hemolytic anemia, thrombocytopenia, and acute kidney injury. Recently, abnormalities in the mechanisms underlying complement regulation have been focused...

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Drugs  5 results see all →

Clinicaltrials.gov  2,397 results

The molecular bases for the association of FHR-1 with atypical hemolytic uremic syndrom...
https://doi.org/10.1182/blood.2020010069
Blood Martin Merinero H, Subías M et. al.

Mar 2nd, 2021 - Factor H-related proteins (FHRs) are a group of partly characterized complement proteins that are thought to promote complement activation by competing binding of factor H (FH) to surface-bound C3b. Among them, FHR-1 is remarkable because is assoc...

Extracellular Vesicles and Renal Endothelial Cells: a Fatal Attraction in Hemolytic Ure...
https://doi.org/10.1016/j.ajpath.2021.02.011
The American Journal of Pathology; Varrone E, Carnicelli D et. al.

Mar 2nd, 2021 - This review will focus on typical hemolytic uremic syndrome (HUS), a life-threatening sequela of human infections caused, particularly in children, by Shiga toxin-producing Escherichia coli strains (STEC). Thrombotic microangiopathy of the brain a...

Serum insulin-like growth factor-binding protein 2 levels as an indicator for disease s...
https://doi.org/10.1080/0886022X.2021.1885445
Renal Failure; Tasaki Y, Inoue N et. al.

Mar 1st, 2021 - Insulin-like growth factor-binding protein (IGFBP) 2 plays an important role in the regulation of cell adhesion, migration, growth, and apoptosis. This study aimed to investigate the clinical significance of serum IGFBP2 as a biomarker for disease...

50 Years Ago in TheJournalofPediatrics: Therapy of Hemolytic Uremic Syndrome, a 50-Year...
https://doi.org/10.1016/j.jpeds.2020.11.039
The Journal of Pediatrics; Salinas Silva CA, Ortega Alonzo SE

Feb 26th, 2021 - 50 Years Ago in TheJournalofPediatrics: Therapy of Hemolytic Uremic Syndrome, a 50-Year Update.|2021|Salinas Silva CA,Ortega Alonzo SE,|

Genomic Characterization of hlyF-positive Shiga Toxin-Producing Escherichia coli, Italy...
https://doi.org/10.3201/eid2703.203110
Emerging Infectious Diseases; Gigliucci F, van Hoek AHAM et. al.

Feb 24th, 2021 - Shiga toxin-producing Escherichia coli (STEC) O80:H2 has emerged in Europe as a cause of hemolytic uremic syndrome associated with bacteremia. STEC O80:H2 harbors the mosaic plasmid pR444_A, which combines several virulence genes, including hlyF a...

see more →

News  91 results

FDA Clears Ravulizumab for Atypical Hemolytic Uremic Syndrome
https://www.medscape.com/viewarticle/920120

Oct 20th, 2019 - The US Food and Drug Administration (FDA) has approved ravulizumab (Ultomiris, Alexion Pharmaceuticals) to inhibit complement-mediated thrombotic microangiopathy (TMA) in adults and children age 1 month or older with atypical hemolytic uremic synd...

Hemolytic Uremic Syndrome With Severe Neurologic Complications in an Adult
https://www.mdedge.com/fedprac/article/202331/neurology/hemolytic-uremic-syndrome-severe-neurologic-complications-adult?channel=258
Ayan Nasir*, Nimai Patel* et. al.

Jun 5th, 2019 - Hemolytic uremic syndrome (HUS) is a rare illness that can be acquired through the consumption of food products contaminated with strains of Shiga toxin-producing Escherichia coli (E coli ; STEC). 1 Between 6% and 15% of individuals infected with.

June 2019 Management of Neurologic Disorders in Federal Health Care
https://www.mdedge.com/fedprac/article/203582/june-2019-management-neurologic-disorders-federal-health-care?channel=27011

Jun 1st, 2019 - Click here to access June 2019 Management of Neurologic Disorders in Federal Health Care Table of Contents Early and Accurate Identification of Parkinson Disease Among US Veterans Proton Pump Inhibitor Use and Risk of Dementia in the Veteran Popul.

Outbreak of E. coli Infections
https://www.cdc.gov/ecoli/2019/o103-04-19/index.html

Apr 4th, 2019 - As of April 4, 2019, 72 people infected with the outbreak strain of E. coli O103 have been reported from five states. Eight people have been hospitalized. No cases of hemolytic uremic syndrome (HUS) or deaths have been reported.

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Patient Education  4 results see all →