ALLMedicine™ Heparin-induced Thrombocytopenia Center
Research & Reviews 2,115 results
https://doi.org/10.1016/j.thromres.2021.02.017
Thrombosis Research; Soares Ferreira Júnior A, Boyle SH et. al.
Feb 23rd, 2021 - In heparin-induced thrombocytopenia (HIT), selected patients are treated with therapies directed at the immune response, intravenous immunoglobulin (IVIG) and therapeutic plasma exchange (TPE). To determine IVIG and TPE characteristics and outcome...
https://doi.org/10.1007/s11239-020-02320-3 10.1016/j.jacc.2016.02.073 10.1056/NEJMcp1411910 10.1038/s41467-019-09160-7 10.1177/2050313x14533945 10.1111/j.1538-7836.2005.01204.x 10.1111/j.1365-2141.2011.08746.x 10.1586/17474086.1.1.75 10.1200/JCO.19.01461 10.1160/TH08-09-0563 10.1016/j.thromres.2014.11.032 10.2147/DDDT.S106153 10.1002/ajh.20098 10.1111/bjh.16400 10.1002/rth2.12145 10.1007/s12185-017-2271-8 10.1160/TH05-07-0489 10.1055/s-0037-1615946 10.1016/j.jacc.2017.09.1099 10.1182/blood-2017-04-778993 10.1159/000280466 10.1007/s11239-017-1566-1 10.1155/2017/9876819 10.1126/scitranslmed.aan8292 10.1002/ajh.21128 10.1111/bjh.13874 10.1186/s13045-016-0242-9
Journal of Thrombosis and Thrombolysis; Lai CMB, Smith T et. al.
Feb 14th, 2021 - Heparin-induced thrombocytopenia (HIT) is a highly thrombogenic condition. Cancer patients are already at high risk of thrombosis. The treatment and outcomes of HIT in cancer patients are not well established. We retrospectively identified patient...
https://doi.org/10.1111/jth.15262
Journal of Thrombosis and Haemostasis : JTH; Brodard J, Kremer Hovinga JA et. al.
Feb 7th, 2021 - Heparin-induced thrombocytopenia (HIT) is a severe adverse reaction to heparin caused by heparin-dependent, platelet activating anti-platelet factor 4 (PF4)/heparin antibodies. Heparin is a cornerstone of treatment in critically ill COVID-19 patie...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4357587
Journal of Paediatrics and Child Health; Sheath C, Abdelrahman M et. al.
Feb 2nd, 2021 - Antibodies specific for platelet factor 4 (PF4)/heparin complexes are central to the pathogenesis of heparin-induced thrombocytopenia. Marginal zone B cells appear to be the source of such antibodies, but whether T-cell help is required is unclear...
https://doi.org/10.1002/jca.21876
Journal of Clinical Apheresis REFERENCES; Soares Ferreira Júnior A, Boyle SH et. al.
Jan 16th, 2021 - Heparin-induced thrombocytopenia (HIT) is characterized by anti-heparin/platelet factor 4 immune complexes, which are removed by therapeutic plasma exchange (TPE). Our main objective was to study TPE outcomes in HIT using a large administrative cl...
Guidelines 7 results
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6258919
Blood Advances; Cuker A, Arepally GM et. al.
Nov 29th, 2018 - Heparin-induced thrombocytopenia (HIT) is an adverse drug reaction mediated by platelet-activating antibodies that target complexes of platelet factor 4 and heparin. Patients are at markedly increased risk of thromboembolism. These evidence-based ...
http://www.bloodadvances.org/content/2/22/3360
Cuker, A.
Nov 26th, 2018 - Background: Heparin-induced thrombocytopenia (HIT) is an adverse drug reaction mediated by platelet-activating antibodies that target complexes of platelet factor 4 and heparin. Patients are at markedly increased risk of thromboembolism.
https://doi.org/10.1111/jth.13516
Journal of Thrombosis and Haemostasis : JTH; Morel-Kopp MC, Mullier F et. al.
Nov 19th, 2016 - Heparin-induced multi-electrode aggregometry method for heparin-induced thrombocytopenia testing: communication from the SSC of the ISTH.|2016|Morel-Kopp MC,Mullier F,Gkalea V,Bakchoul T,Minet V,|adverse effects,adverse effects,drug effects,instru...
https://doi.org/10.1111/bjh.12059
British Journal of Haematology; Watson H, Davidson S et. al.
Oct 9th, 2012 - Guidelines on the diagnosis and management of heparin-induced thrombocytopenia: second edition.|2012|Watson H,Davidson S,Keeling D, ,|adverse effects,adverse effects,chemically induced,diagnosis,therapy,
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3278058
Chest Linkins LA, Dans AL et. al.
Feb 14th, 2012 - Heparin-induced thrombocytopenia (HIT) is an antibody-mediated adverse drug reaction that can lead to devastating thromboembolic complications, including pulmonary embolism, ischemic limb necrosis necessitating limb amputation, acute myocardial in...
Drugs 77 results see all →
Clinicaltrials.gov 2,225 results
https://doi.org/10.1016/j.thromres.2021.02.017
Thrombosis Research; Soares Ferreira Júnior A, Boyle SH et. al.
Feb 23rd, 2021 - In heparin-induced thrombocytopenia (HIT), selected patients are treated with therapies directed at the immune response, intravenous immunoglobulin (IVIG) and therapeutic plasma exchange (TPE). To determine IVIG and TPE characteristics and outcome...
https://doi.org/10.1007/s11239-020-02320-3 10.1016/j.jacc.2016.02.073 10.1056/NEJMcp1411910 10.1038/s41467-019-09160-7 10.1177/2050313x14533945 10.1111/j.1538-7836.2005.01204.x 10.1111/j.1365-2141.2011.08746.x 10.1586/17474086.1.1.75 10.1200/JCO.19.01461 10.1160/TH08-09-0563 10.1016/j.thromres.2014.11.032 10.2147/DDDT.S106153 10.1002/ajh.20098 10.1111/bjh.16400 10.1002/rth2.12145 10.1007/s12185-017-2271-8 10.1160/TH05-07-0489 10.1055/s-0037-1615946 10.1016/j.jacc.2017.09.1099 10.1182/blood-2017-04-778993 10.1159/000280466 10.1007/s11239-017-1566-1 10.1155/2017/9876819 10.1126/scitranslmed.aan8292 10.1002/ajh.21128 10.1111/bjh.13874 10.1186/s13045-016-0242-9
Journal of Thrombosis and Thrombolysis; Lai CMB, Smith T et. al.
Feb 14th, 2021 - Heparin-induced thrombocytopenia (HIT) is a highly thrombogenic condition. Cancer patients are already at high risk of thrombosis. The treatment and outcomes of HIT in cancer patients are not well established. We retrospectively identified patient...
https://doi.org/10.1111/jth.15262
Journal of Thrombosis and Haemostasis : JTH; Brodard J, Kremer Hovinga JA et. al.
Feb 7th, 2021 - Heparin-induced thrombocytopenia (HIT) is a severe adverse reaction to heparin caused by heparin-dependent, platelet activating anti-platelet factor 4 (PF4)/heparin antibodies. Heparin is a cornerstone of treatment in critically ill COVID-19 patie...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4357587
Journal of Paediatrics and Child Health; Sheath C, Abdelrahman M et. al.
Feb 2nd, 2021 - Antibodies specific for platelet factor 4 (PF4)/heparin complexes are central to the pathogenesis of heparin-induced thrombocytopenia. Marginal zone B cells appear to be the source of such antibodies, but whether T-cell help is required is unclear...
https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=b5143563-ff45-433a-a9e2-f8b8340db1f5
Jan 31st, 2021 - Argatroban is a direct thrombin inhibitor indicated: For prophylaxis or treatment of thrombosis in adult patients with heparin-induced thrombocytopenia (HIT). (1.1) As an anticoagulant in adults patients with or at risk for HIT undergoing percuta...
News 69 results
https://www.staging.medscape.com/viewarticle/906609
Dec 13th, 2018 - SAN DIEGO — Three clinicians were hailed as Choosing Wisely Champions here at the American Society of Hematology (ASH) 2018 annual meeting for their efforts to reduce overuse of treatments and tests. One clinician describes how his team managed to...
https://www.medscape.com/viewarticle/906609
Dec 13th, 2018 - SAN DIEGO — Three clinicians were hailed as Choosing Wisely Champions here at the American Society of Hematology (ASH) 2018 annual meeting for their efforts to reduce overuse of treatments and tests. One clinician describes how his team managed to...
https://www.mdedge.com/hematology-oncology/article/162865/thrombosis/two-scoring-systems-helpful-diagnosing-heparin-induced/page/0/1
Apr 8th, 2018 - At the prespecified screening cut-off of 2 or more points, the HEP Score was 97. 7% sensitive and 21.
https://www.mdedge.com/hematology-oncology/article/185038/anemia/test-hit-receives-ce-mark
HT Staff
Apr 4th, 2018 - Platelet-rich plasma HIT Confirm, a test used to diagnose heparin-induced thrombocytopenia (HIT), has received the CE mark. This means the test meets regulatory requirements and health, safety, and environmental protection standards for products s.
https://www.medpagetoday.com/cardiology/prevention/70638
Jan 20th, 2018 - Action Points The first-ever clinical practice guidelines aimed at standardizing the use of blood thinners during heart surgery emphasize optimal heparin dosing during bypass, identification of contraindications to heparin use and heparin alternat...