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About 4,493 results

ALLMedicine™ Heparin-induced Thrombocytopenia Center

Research & Reviews  2,115 results

A population-based analysis on the use of therapeutic plasma exchange and intravenous i...
https://doi.org/10.1016/j.thromres.2021.02.017
Thrombosis Research; Soares Ferreira Júnior A, Boyle SH et. al.

Feb 23rd, 2021 - In heparin-induced thrombocytopenia (HIT), selected patients are treated with therapies directed at the immune response, intravenous immunoglobulin (IVIG) and therapeutic plasma exchange (TPE). To determine IVIG and TPE characteristics and outcome...

COVID-19 patients often show high-titer non-platelet-activating anti-PF4/heparin IgG an...
https://doi.org/10.1111/jth.15262
Journal of Thrombosis and Haemostasis : JTH; Brodard J, Kremer Hovinga JA et. al.

Feb 7th, 2021 - Heparin-induced thrombocytopenia (HIT) is a severe adverse reaction to heparin caused by heparin-dependent, platelet activating anti-platelet factor 4 (PF4)/heparin antibodies. Heparin is a cornerstone of treatment in critically ill COVID-19 patie...

Paediatric appendicitis during the COVID-19 pandemic.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4357587
Journal of Paediatrics and Child Health; Sheath C, Abdelrahman M et. al.

Feb 2nd, 2021 - Antibodies specific for platelet factor 4 (PF4)/heparin complexes are central to the pathogenesis of heparin-induced thrombocytopenia. Marginal zone B cells appear to be the source of such antibodies, but whether T-cell help is required is unclear...

Use of therapeutic plasma exchange in heparin-induced thrombocytopenia: A population-ba...
https://doi.org/10.1002/jca.21876
Journal of Clinical Apheresis REFERENCES; Soares Ferreira Júnior A, Boyle SH et. al.

Jan 16th, 2021 - Heparin-induced thrombocytopenia (HIT) is characterized by anti-heparin/platelet factor 4 immune complexes, which are removed by therapeutic plasma exchange (TPE). Our main objective was to study TPE outcomes in HIT using a large administrative cl...

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Guidelines  7 results

American Society of Hematology 2018 guidelines for management of venous thromboembolism...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6258919
Blood Advances; Cuker A, Arepally GM et. al.

Nov 29th, 2018 - Heparin-induced thrombocytopenia (HIT) is an adverse drug reaction mediated by platelet-activating antibodies that target complexes of platelet factor 4 and heparin. Patients are at markedly increased risk of thromboembolism. These evidence-based ...

American Society of Hematology 2018 guidelines for management of venous thromboembolism: hep...
http://www.bloodadvances.org/content/2/22/3360
Cuker, A.

Nov 26th, 2018 - Background: Heparin-induced thrombocytopenia (HIT) is an adverse drug reaction mediated by platelet-activating antibodies that target complexes of platelet factor 4 and heparin. Patients are at markedly increased risk of thromboembolism.

Heparin-induced multi-electrode aggregometry method for heparin-induced thrombocytopeni...
https://doi.org/10.1111/jth.13516
Journal of Thrombosis and Haemostasis : JTH; Morel-Kopp MC, Mullier F et. al.

Nov 19th, 2016 - Heparin-induced multi-electrode aggregometry method for heparin-induced thrombocytopenia testing: communication from the SSC of the ISTH.|2016|Morel-Kopp MC,Mullier F,Gkalea V,Bakchoul T,Minet V,|adverse effects,adverse effects,drug effects,instru...

Guidelines on the diagnosis and management of heparin-induced thrombocytopenia: second ...
https://doi.org/10.1111/bjh.12059
British Journal of Haematology; Watson H, Davidson S et. al.

Oct 9th, 2012 - Guidelines on the diagnosis and management of heparin-induced thrombocytopenia: second edition.|2012|Watson H,Davidson S,Keeling D, ,|adverse effects,adverse effects,chemically induced,diagnosis,therapy,

Treatment and prevention of heparin-induced thrombocytopenia: Antithrombotic Therapy an...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3278058
Chest Linkins LA, Dans AL et. al.

Feb 14th, 2012 - Heparin-induced thrombocytopenia (HIT) is an antibody-mediated adverse drug reaction that can lead to devastating thromboembolic complications, including pulmonary embolism, ischemic limb necrosis necessitating limb amputation, acute myocardial in...

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Drugs  77 results see all →

Clinicaltrials.gov  2,225 results

A population-based analysis on the use of therapeutic plasma exchange and intravenous i...
https://doi.org/10.1016/j.thromres.2021.02.017
Thrombosis Research; Soares Ferreira Júnior A, Boyle SH et. al.

Feb 23rd, 2021 - In heparin-induced thrombocytopenia (HIT), selected patients are treated with therapies directed at the immune response, intravenous immunoglobulin (IVIG) and therapeutic plasma exchange (TPE). To determine IVIG and TPE characteristics and outcome...

COVID-19 patients often show high-titer non-platelet-activating anti-PF4/heparin IgG an...
https://doi.org/10.1111/jth.15262
Journal of Thrombosis and Haemostasis : JTH; Brodard J, Kremer Hovinga JA et. al.

Feb 7th, 2021 - Heparin-induced thrombocytopenia (HIT) is a severe adverse reaction to heparin caused by heparin-dependent, platelet activating anti-platelet factor 4 (PF4)/heparin antibodies. Heparin is a cornerstone of treatment in critically ill COVID-19 patie...

Paediatric appendicitis during the COVID-19 pandemic.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4357587
Journal of Paediatrics and Child Health; Sheath C, Abdelrahman M et. al.

Feb 2nd, 2021 - Antibodies specific for platelet factor 4 (PF4)/heparin complexes are central to the pathogenesis of heparin-induced thrombocytopenia. Marginal zone B cells appear to be the source of such antibodies, but whether T-cell help is required is unclear...

Argatroban - argatroban injection-Caplin Steriles Limited
https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=b5143563-ff45-433a-a9e2-f8b8340db1f5

Jan 31st, 2021 - Argatroban is a direct thrombin inhibitor indicated: For prophylaxis or treatment of thrombosis in adult patients with heparin-induced thrombocytopenia (HIT). (1.1)  As an anticoagulant in adults patients with or at risk for HIT undergoing percuta...

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News  69 results

Choosing Wisely Champions Cut Blood RBC Transfusions, HIT testing
https://www.staging.medscape.com/viewarticle/906609

Dec 13th, 2018 - SAN DIEGO — Three clinicians were hailed as Choosing Wisely Champions here at the American Society of Hematology (ASH) 2018 annual meeting for their efforts to reduce overuse of treatments and tests. One clinician describes how his team managed to...

Choosing Wisely Champions Cut Blood RBC Transfusions, HIT testing
https://www.medscape.com/viewarticle/906609

Dec 13th, 2018 - SAN DIEGO — Three clinicians were hailed as Choosing Wisely Champions here at the American Society of Hematology (ASH) 2018 annual meeting for their efforts to reduce overuse of treatments and tests. One clinician describes how his team managed to...

Test for HIT receives CE mark
https://www.mdedge.com/hematology-oncology/article/185038/anemia/test-hit-receives-ce-mark
HT Staff

Apr 4th, 2018 - Platelet-rich plasma HIT Confirm, a test used to diagnose heparin-induced thrombocytopenia (HIT), has received the CE mark. This means the test meets regulatory requirements and health, safety, and environmental protection standards for products s.

New Guidelines Address Use of Blood Thinners During Bypass Surgery
https://www.medpagetoday.com/cardiology/prevention/70638

Jan 20th, 2018 - Action Points The first-ever clinical practice guidelines aimed at standardizing the use of blood thinners during heart surgery emphasize optimal heparin dosing during bypass, identification of contraindications to heparin use and heparin alternat...

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