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ALLMedicine™ Hereditary Hemorrhagic Telangiectasia Center

Research & Reviews  1,275 results

Hereditary Hemorrhagic Telangiectasia: The Convergence of Genotype, Phenotype, and Imag...
https://doi.org/10.1148/radiol.2021203487
Radiology Hetts SW, Shieh JT et. al.

May 11th, 2021 - Hereditary hemorrhagic telangiectasia (HHT) is an autosomal dominant disease that manifests as vascular malformations in the brain, lung, liver, gastrointestinal tract, nasal mucosa, and skin. Diagnosis and management of HHT is guided in large par...

Treatment of pulmonary hypertension in patients with Hereditary Hemorrhagic Telangiecta...
https://doi.org/10.1016/j.pupt.2021.102033
Pulmonary Pharmacology & Therapeutics; Abston E, Hon S et. al.

Apr 25th, 2021 - Pulmonary Arterial Hypertension (PAH), a rare complication of HHT is associated with poor outcome. There are no trials to date that have investigated whether pulmonary vasodilator therapy improves hemodynamics or survival in this disease. To deter...

Endoglin deficiency impairs VEGFR2 but not FGFR1 or TIE2 activation and alters VEGF-med...
https://doi.org/10.1016/j.trsl.2021.04.005
Translational Research : the Journal of Laboratory and Cl... Zhang Q, Wang C et. al.

Apr 24th, 2021 - Hereditary hemorrhagic telangiectasia (HHT) is a genetic disease characterized by vascular dysplasia. Mutations of the endoglin (ENG) gene that encodes a co-receptor of the transforming growth factor β1 signaling pathway cause type I HHT. ENG is p...

Adrenomedullin as a potential biomarker involved in patients with hereditary hemorrhagi...
https://doi.org/10.1016/j.ejim.2021.03.039
European Journal of Internal Medicine; Iriarte A, Ochoa-Callejero L et. al.

Apr 23rd, 2021 - Adrenomedullin (AM) is a vasoactive peptide mostly secreted by endothelial cells with an important role in preserving endothelial integrity.  The relationship between AM and hereditary hemorrhagic telangiectasia (HHT) is unknown. We aimed to compa...

Rapid Sequence Induction and Intubation for Patients With Hereditary Hemorrhagic Telang...
https://doi.org/10.1001/jamaoto.2021.0413
JAMA Otolaryngology-- Head & Neck Surgery; Safi C, Troob S et. al.

Apr 15th, 2021 - Rapid Sequence Induction and Intubation for Patients With Hereditary Hemorrhagic Telangiectasia.|2021|Safi C,Troob S,Gudis DA,|

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Guidelines  3 results

Second International Guidelines for the Diagnosis and Management of Hereditary Hemorrha...
https://doi.org/10.7326/M20-1443
Annals of Internal Medicine; Faughnan ME, Mager JJ et. al.

Sep 7th, 2020 - Hereditary hemorrhagic telangiectasia (HHT) is an autosomal dominant disease with an estimated prevalence of 1 in 5000 that is characterized by the presence of vascular malformations (VMs). These result in chronic bleeding, acute hemorrhage, and c...

Hereditary hemorrhagic telangiectasia and liver involvement: Vascular liver diseases: p...
https://doi.org/10.1016/j.clinre.2020.03.008
Clinics and Research in Hepatology and Gastroenterology; Silvain C, Thévenot T et. al.

Apr 6th, 2020 - Hereditary hemorrhagic telangiectasia and liver involvement: Vascular liver diseases: position papers from the francophone network for vascular liver diseases, the French Association for the Study of the Liver (AFEF), and ERN-rare liver.|2020|Silv...

Second International Guidelines for the Diagnosis and Management of Hereditary Hemorrhagic Telangiectasia
https://www.acpjournals.org/doi/10.7326/M20-1443
Annals of Internal Medicine; Faughnan, ME et. al.

Hereditary hemorrhagic telangiectasia (HHT) is an autosomal dominant disease with an estimated prevalence of 1 in 5000 that is characterized by the presence of vascular malformations (VMs). These result in chronic bleeding, acute hemorrhage, and c...

see more →

Clinicaltrials.gov  1,303 results

Hereditary Hemorrhagic Telangiectasia: The Convergence of Genotype, Phenotype, and Imag...
https://doi.org/10.1148/radiol.2021203487
Radiology Hetts SW, Shieh JT et. al.

May 11th, 2021 - Hereditary hemorrhagic telangiectasia (HHT) is an autosomal dominant disease that manifests as vascular malformations in the brain, lung, liver, gastrointestinal tract, nasal mucosa, and skin. Diagnosis and management of HHT is guided in large par...

Treatment of pulmonary hypertension in patients with Hereditary Hemorrhagic Telangiecta...
https://doi.org/10.1016/j.pupt.2021.102033
Pulmonary Pharmacology & Therapeutics; Abston E, Hon S et. al.

Apr 25th, 2021 - Pulmonary Arterial Hypertension (PAH), a rare complication of HHT is associated with poor outcome. There are no trials to date that have investigated whether pulmonary vasodilator therapy improves hemodynamics or survival in this disease. To deter...

Endoglin deficiency impairs VEGFR2 but not FGFR1 or TIE2 activation and alters VEGF-med...
https://doi.org/10.1016/j.trsl.2021.04.005
Translational Research : the Journal of Laboratory and Cl... Zhang Q, Wang C et. al.

Apr 24th, 2021 - Hereditary hemorrhagic telangiectasia (HHT) is a genetic disease characterized by vascular dysplasia. Mutations of the endoglin (ENG) gene that encodes a co-receptor of the transforming growth factor β1 signaling pathway cause type I HHT. ENG is p...

Adrenomedullin as a potential biomarker involved in patients with hereditary hemorrhagi...
https://doi.org/10.1016/j.ejim.2021.03.039
European Journal of Internal Medicine; Iriarte A, Ochoa-Callejero L et. al.

Apr 23rd, 2021 - Adrenomedullin (AM) is a vasoactive peptide mostly secreted by endothelial cells with an important role in preserving endothelial integrity.  The relationship between AM and hereditary hemorrhagic telangiectasia (HHT) is unknown. We aimed to compa...

Rapid Sequence Induction and Intubation for Patients With Hereditary Hemorrhagic Telang...
https://doi.org/10.1001/jamaoto.2021.0413
JAMA Otolaryngology-- Head & Neck Surgery; Safi C, Troob S et. al.

Apr 15th, 2021 - Rapid Sequence Induction and Intubation for Patients With Hereditary Hemorrhagic Telangiectasia.|2021|Safi C,Troob S,Gudis DA,|

see more →

News  35 results

Second International Hereditary Hemorrhagic Telangiectasia (HHT) Guidelines (2020)
https://reference.staging.medscape.com/viewarticle/938166

Sep 29th, 2020 - The Second International Hereditary Hemorrhagic Telangiectasia (HHT) Guidelines were published on September 8, 2020.[1] Management of Epistaxis To reduce HHT-related epistaxis, use moisturizing topical therapies that humidify the nasal mucosa. Con...

Second International Hereditary Hemorrhagic Telangiectasia (HHT) Guidelines (2020)
https://reference.medscape.com/viewarticle/938166

Sep 29th, 2020 - The Second International Hereditary Hemorrhagic Telangiectasia (HHT) Guidelines were published on September 8, 2020.[1] Management of Epistaxis To reduce HHT-related epistaxis, use moisturizing topical therapies that humidify the nasal mucosa. Con...

New Guidelines Expand Management Options for Hereditary Hemorrhagic Telangiectasia
https://www.staging.medscape.com/viewarticle/937096

Sep 9th, 2020 - NEW YORK (Reuters Health) - New guidelines provide updated advice on managing epistaxis and vascular malformations and new recommendations for managing gastrointestinal (GI) bleeding, anemia, pediatric care, and pregnancy and delivery. The expert ...

New Guidelines Expand Management Options for Hereditary Hemorrhagic Telangiectasia
https://www.medscape.com/viewarticle/937096

Sep 9th, 2020 - NEW YORK (Reuters Health) - New guidelines provide updated advice on managing epistaxis and vascular malformations and new recommendations for managing gastrointestinal (GI) bleeding, anemia, pediatric care, and pregnancy and delivery. The expert ...

Drug Shows 'Striking' Efficacy in Hereditary Bleeding Disorder
https://www.medscape.com/viewarticle/932558

Jun 17th, 2020 - Bevacizumab has shown efficacy in the treatment of hereditary hemorrhagic telangiectasia (HHT), a rare, progressive bleeding disorder for which there are currently no approved therapies. The finding comes from the InHIBIT-Bleed trial, results from...

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Patient Education  7 results see all →