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About 2,882 results

ALLMedicine™ Primary Central Nervous System Lymphoma Center

Research & Reviews  1,421 results

Resection of primary central nervous system lymphoma: impact of patient selection on ov...
https://doi.org/10.3171/2020.9.JNS201980
Journal of Neurosurgery; Schellekes N, Barbotti A et. al.

Feb 26th, 2021 - Primary central nervous system lymphoma (PCNSL) is a rare CNS tumor with a poor prognosis. It is usually diagnosed by needle biopsy and treated mainly with high-dose chemotherapy. Resection is currently not considered a standard treatment option. ...

MYD88 L265P mutation and interleukin-10 detection in cerebrospinal fluid are highly spe...
https://doi.org/10.1111/bjh.17357
British Journal of Haematology; Ferreri AJM, Calimeri T et. al.

Feb 23rd, 2021 - Reliable biomarkers are needed to avoid diagnostic delay and its devastating effects in patients with primary central nervous system (CNS) lymphoma (PCNSL). We analysed the discriminating sensitivity and specificity of myeloid differentiation prim...

Changes in cerebrospinal fluid interleukin-10 levels display better performance in pred...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7898756
BMC Cancer; Zhang Y, Zou D et. al.

Feb 23rd, 2021 - Establishing diagnostic and prognostic biomarkers of primary central nervous system lymphoma (PCNSL) is a challenge. This study evaluated the value of dynamic interleukin (IL)-10 cerebrospinal fluid (CSF) concentrations for prognosis and relapse p...

Foundations of Neuro-Oncology: A Multidisciplinary Approach.
https://doi.org/10.1016/j.wneu.2021.02.059
World Neurosurgery; Barbaro M, Fine HA et. al.

Feb 22nd, 2021 - Neuro-oncology is a branch of medicine focused on the diagnosis and treatment of primary and secondary tumors of the nervous system as well as the neurologic complications of cancer and cancer treatments. In practice, neuro-oncologists require an ...

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Clinicaltrials.gov  1,439 results

Resection of primary central nervous system lymphoma: impact of patient selection on ov...
https://doi.org/10.3171/2020.9.JNS201980
Journal of Neurosurgery; Schellekes N, Barbotti A et. al.

Feb 26th, 2021 - Primary central nervous system lymphoma (PCNSL) is a rare CNS tumor with a poor prognosis. It is usually diagnosed by needle biopsy and treated mainly with high-dose chemotherapy. Resection is currently not considered a standard treatment option. ...

MYD88 L265P mutation and interleukin-10 detection in cerebrospinal fluid are highly spe...
https://doi.org/10.1111/bjh.17357
British Journal of Haematology; Ferreri AJM, Calimeri T et. al.

Feb 23rd, 2021 - Reliable biomarkers are needed to avoid diagnostic delay and its devastating effects in patients with primary central nervous system (CNS) lymphoma (PCNSL). We analysed the discriminating sensitivity and specificity of myeloid differentiation prim...

Changes in cerebrospinal fluid interleukin-10 levels display better performance in pred...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7898756
BMC Cancer; Zhang Y, Zou D et. al.

Feb 23rd, 2021 - Establishing diagnostic and prognostic biomarkers of primary central nervous system lymphoma (PCNSL) is a challenge. This study evaluated the value of dynamic interleukin (IL)-10 cerebrospinal fluid (CSF) concentrations for prognosis and relapse p...

Foundations of Neuro-Oncology: A Multidisciplinary Approach.
https://doi.org/10.1016/j.wneu.2021.02.059
World Neurosurgery; Barbaro M, Fine HA et. al.

Feb 22nd, 2021 - Neuro-oncology is a branch of medicine focused on the diagnosis and treatment of primary and secondary tumors of the nervous system as well as the neurologic complications of cancer and cancer treatments. In practice, neuro-oncologists require an ...

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News  21 results

Primary CNS lymphoma: R-CHOP hits back
https://www.mdedge.com/hematology-oncology/article/210341/b-cell-lymphoma/primary-cns-lymphoma-r-chop-hits-back?channel=59374
Vanja Zeremski, MD, Thomas Fischer, MD

Oct 17th, 2019 - Primary central nervous system lymphoma (PCNSL) is a rare and aggressive form of non-Hodgkin lymphoma solely confined to the CNS. The majority of PCNSL histologically presents as diffuse large B-cell lymphoma (DLBCL).

Review of Radiologic Considerations in an Immunocompetent Patient With Primary Central Nervous System Lymphoma
https://www.mdedge.com/fedprac/avaho/article/206078/lymphoma-plasma-cell-disorders/review-radiologic-considerations/page/0/1?channel=263

Aug 7th, 2019 - Discussion The workup of altered mental status, focal neurologic deficits, headaches, or other neurologic conditions often begins with a noncontrast CT scan. On CT, PCNSL generally appears isodense to hyperdense to gray matter, but appearance is v.

High-dose MTX-based chemo is well tolerated in older PCNSL patients
https://www.mdedge.com/hematology-oncology/article/199565/b-cell-lymphoma/high-dose-mtx-based-chemo-well-tolerated-older?channel=59374
Will Pass

Apr 24th, 2019 - GLASGOW – Most older patients with primary central nervous system lymphoma (PCNSL) can tolerate high-dose methotrexate-based chemotherapy and achieve similar outcomes as younger and fitter patients, according to a retrospective analysis of 244 pat.

Rituximab boosts survival in primary CNS lymphoma
https://www.mdedge.com/hematology-oncology/article/197142/b-cell-lymphoma/rituximab-boosts-survival-primary-cns-lymphoma?channel=59374
Will Pass

Mar 22nd, 2019 - For patients with primary central nervous system lymphoma (PCNSL), adding rituximab to combination high-dose methotrexate and temozolomide significantly boosted the 5-year overall survival rate, according to a retrospective study. The triplet comb.

New PCNSL guidelines emphasize importance of patient fitness
https://www.mdedge.com/hematology-oncology/article/190772/lymphoma-plasma-cell-disorders/new-pcnsl-guidelines-emphasize-importance?channel=49434
Jennie Smith

Dec 2nd, 2018 - Image by Michael Bonert Micrograph showing PCNSL New guidelines on the diagnosis and management of patients with primary central nervous system lymphoma (PCNSL) emphasize prompt diagnosis, aggressive treatment whenever possible, and multidisciplin.

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Patient Education  1 results see all →