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About 8,016 results

ALLMedicine™ Tuberous Sclerosis Center

Research & Reviews  3,899 results

Association of maternal body mass index with intellectual disability risk.
https://doi.org/10.1136/archdischild-2020-320793
Archives of Disease in Childhood. Fetal and Neonatal Edit... Lee PMY, Tse LA et. al.

Apr 14th, 2021 - The study aimed to investigate the association between maternal body mass index (BMI) in early pregnancy and children's intellectual disability (ID) risk in the absence of chromosomal disorders, neurofibromatosis and tuberous sclerosis, taking adv...

Focal cortical dysplasia: an update on diagnosis and treatment.
https://doi.org/10.1080/14737175.2021.1915135
Expert Review of Neurotherapeutics; Guerrini R, Barba C

Apr 9th, 2021 - Introduction: Focal Cortical Dysplasias (FCDs) represent the most common etiology in pediatric drug-resistant focal epilepsies undergoing surgical treatment. The localization, extent and histopathological features of FCDs are considerably variable...

Innumerable Meningiomas Arising in a Patient With Tuberous Sclerosis Complex Decades Af...
https://doi.org/10.1177/10935266211006078
Pediatric and Developmental Pathology : the Official Jour... Gilani A, Lee JC et. al.

Apr 7th, 2021 - Meningioma is the most common radiation-induced brain neoplasm, usually occurring after a latency of 20 - 35 years, with multiplicity in 10% of cases. Radiation-induced meningiomas (RIMs) have not previously been reported in patients with tuberous...

Topical rapamycin in the treatment of facial angiofibromas in tuberous sclerosis: a sys...
https://doi.org/10.1080/09546634.2021.1905768
The Journal of Dermatological Treatment; Cortell Fuster C, Martínez Gómez MA et. al.

Apr 6th, 2021 - facial angiofibromas of tuberous sclerosis are the most prevalent cutaneous manifestation, affecting 80% of patients, which cause facial lesions with negative psychosocial consequences. Newly, topical rapamycin has been established as an effective...

Predictors and Long-term Outcome of Resective Epilepsy Surgery in Patients with Tuberou...
https://doi.org/10.1016/j.seizure.2021.03.022
Seizure Huang Q, Zhou J et. al.

Apr 3rd, 2021 - To identify prognostic factors and long-term seizure outcomes for patients with tuberous sclerosis complex (TSC) who underwent resective treatment for epilepsy. We enrolled 81 patients with TSC who had undergone resective epilepsy surgery at Sanbo...

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Guidelines  3 results

Imaging of Kidney Cysts and Cystic Kidney Diseases in Children: An International Working Gro...
https://pubs.rsna.org/doi/full/10.1148/radiol.2018181243

Dec 31st, 2018 - Kidney cysts can manifest as focal disease (simple and complex kidney cysts), affect a whole kidney (eg, multicystic dysplastic kidney or cystic dysplasia), or manifest as bilateral cystic disease (eg, autosomal recessive polycystic kidney disease.

Cardiovascular manifestations of tuberous sclerosis complex and summary of the revised ...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4338742
Journal of the American Heart Association; Hinton RB, Prakash A et. al.

Nov 26th, 2014 - Cardiovascular manifestations of tuberous sclerosis complex and summary of the revised diagnostic criteria and surveillance and management recommendations from the International Tuberous Sclerosis Consensus Group.|2014|Hinton RB,Prakash A,Romp RL,...

Kidney damage due to tuberous sclerosis complex: management recommendations.
https://doi.org/10.1016/j.diii.2013.01.003
Diagnostic and Interventional Imaging; Rouvière O, Nivet H et. al.

Feb 18th, 2013 - To deduce recommendations from the literature on the management of kidney damage caused by tuberous sclerosis complex (TSC). Five practitioners have written up recommendations after reviewing the literature. They were evaluated by 14 experts using...

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Drugs  7 results see all →

Clinicaltrials.gov  3,981 results

Association of maternal body mass index with intellectual disability risk.
https://doi.org/10.1136/archdischild-2020-320793
Archives of Disease in Childhood. Fetal and Neonatal Edit... Lee PMY, Tse LA et. al.

Apr 14th, 2021 - The study aimed to investigate the association between maternal body mass index (BMI) in early pregnancy and children's intellectual disability (ID) risk in the absence of chromosomal disorders, neurofibromatosis and tuberous sclerosis, taking adv...

Focal cortical dysplasia: an update on diagnosis and treatment.
https://doi.org/10.1080/14737175.2021.1915135
Expert Review of Neurotherapeutics; Guerrini R, Barba C

Apr 9th, 2021 - Introduction: Focal Cortical Dysplasias (FCDs) represent the most common etiology in pediatric drug-resistant focal epilepsies undergoing surgical treatment. The localization, extent and histopathological features of FCDs are considerably variable...

Innumerable Meningiomas Arising in a Patient With Tuberous Sclerosis Complex Decades Af...
https://doi.org/10.1177/10935266211006078
Pediatric and Developmental Pathology : the Official Jour... Gilani A, Lee JC et. al.

Apr 7th, 2021 - Meningioma is the most common radiation-induced brain neoplasm, usually occurring after a latency of 20 - 35 years, with multiplicity in 10% of cases. Radiation-induced meningiomas (RIMs) have not previously been reported in patients with tuberous...

Everolimus - everolimus tablet-Natco Pharma Limited
https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=e3dbbc24-7e55-4069-a305-e2cded2db641

Apr 6th, 2021 - Everolimus tablets are a kinase inhibitor indicated for the treatment of: Adults with advanced renal cell carcinoma (RCC) after failure of treatment with sunitinib or sorafenib. (1.3) Adults with renal angiomyolipoma and tuberous sclerosis complex...

Topical rapamycin in the treatment of facial angiofibromas in tuberous sclerosis: a sys...
https://doi.org/10.1080/09546634.2021.1905768
The Journal of Dermatological Treatment; Cortell Fuster C, Martínez Gómez MA et. al.

Apr 6th, 2021 - facial angiofibromas of tuberous sclerosis are the most prevalent cutaneous manifestation, affecting 80% of patients, which cause facial lesions with negative psychosocial consequences. Newly, topical rapamycin has been established as an effective...

see more →

News  119 results

Preventive Treatment Delays First Seizure Onset in Tuberous Sclerosis Complex
https://www.medscape.com/viewarticle/939609

Oct 21st, 2020 - In patients with tuberous sclerosis complex (TSC), preventive treatment with vigabatrin is safe and changes the natural history of seizures, according to research presented at the 2020 CNS-ICNA Conjoint Meeting, held virtually this year. This trea...

FDA Approves Cannabidiol for Tuberous Sclerosis Complex
https://www.staging.medscape.com/viewarticle/935067

Aug 2nd, 2020 - The cannabidiol (CBD) oral solution Epidiolex has been approved by the US Food and Drug Administration (FDA) for the new indication of treatment of seizures associated with tuberous sclerosis complex in patients 1 year of age and older. The drug w...

FDA Approves Cannabidiol for Tuberous Sclerosis Complex
https://www.medscape.com/viewarticle/935067

Aug 2nd, 2020 - The cannabidiol (CBD) oral solution Epidiolex has been approved by the US Food and Drug Administration (FDA) for the new indication of treatment of seizures associated with tuberous sclerosis complex in patients 1 year of age and older. The drug w...

EEG surveillance, preseizure treatment prevents TSC epilepsy, cognitive loss
https://www.mdedge.com/jcomjournal/article/214984/epilepsy-seizures/eeg-surveillance-preseizure-treatment-prevents-tsc?channel=325
M. Alexander Otto

Jan 3rd, 2020 - BALTIMORE – Monitoring children who have tuberous sclerosis with EEG and treating them with vigabatrin (Sabril) at the first sign of preseizure abnormalities, rather than the usual practice of no surveillance and waiting until they have seizures,.

High infantile spasm risk should contraindicate sodium channel blocker antiepileptics
https://www.mdedge.com/neurology/epilepsyresourcecenter/article/214010/epilepsy-seizures/high-infantile-spasm-risk-should?channel=53
M. Alexander Otto

Dec 10th, 2019 - BALTIMORE – Sodium channel blocker antiepileptic drugs increase the risk of infantile spasms sevenfold in children with Down syndrome, tuberous sclerosis complex, hypoxic-ischemic encephalopathy, and other nonsyndromic epilepsy conditions with inf.

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Patient Education  7 results see all →