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About 1,515 results

ALLMedicine™ Von Hippel-Lindau Disease Center

Research & Reviews  747 results

MK-6482 as a potential treatment for von Hippel-Lindau disease-associated clear cell re...
https://doi.org/10.1080/13543784.2021.1925248
Expert Opinion on Investigational Drugs; Hasanov E, Jonasch E

May 4th, 2021 - Von Hippel-Lindau (VHL) disease is an inherited autosomal dominant syndrome caused by a germline mutation and/or deletion of the VHL gene. Inappropriate hypoxia inducible factor (HIF) meditated transcription of proangiogenic and metabolic genes le...

Von Hippel-Lindau disease and rapidly progressing pheochromocytomas in siblings.
https://doi.org/10.1007/s10689-021-00252-2 10.1136/jmg.28.7.443 10.1007/BF03346370 10.1001/archopht.125.2.239 10.1002/humu.20385 10.1016/j.jpurol.2010.12.007 10.1016/S0300-2977(01)00165-6 10.1158/1078-0432.CCR-17-0547 10.1016/j.jpedsurg.2012.07.003 10.1016/j.juro.2010.06.102 10.1016/j.juro.2010.12.050 10.1210/js.2019-00225 10.1002/ajmg.a.33760
Familial Cancer; Fugaru I, Goudie C et. al.

Apr 20th, 2021 - Von Hippel-Lindau (VHL) disease is an autosomal dominant inherited condition with a predisposition to the development of a variety of tumors including pheochromocytomas. A number of cancer surveillance protocols for patients with VHL have been dev...

Impact of Pancreatic Neuroendocrine Tumor on Mortality in Patients with von Hippel-Lind...
https://doi.org/10.1016/j.eprac.2021.03.005
Endocrine Practice : Official Journal of the American Col... Arnon L, Halperin R et. al.

Mar 19th, 2021 - The main causes for morbidity and mortality in von Hippel-Lindau (VHL) disease are central nervous system hemangioblastoma and clear cell renal cell carcinoma, whereas the effect of VHL-related pancreatic neuroendocrine tumors (PNET) on patient ou...

Multiple Hepatic and Pulmonary Tumours Combined with Bilateral Adrenal Masses in a Youn...
https://doi.org/10.1053/j.gastro.2021.02.033
Gastroenterology Kolokotronis T, Reis H

Feb 21st, 2021 - Multiple Hepatic and Pulmonary Tumours Combined with Bilateral Adrenal Masses in a Young Female with von Hippel-Lindau Disease.|2021|Kolokotronis T,Reis H,|

Retrobulbar Hemangioblastomas in von Hippel-Lindau Disease: Clinical Course and Managem...
https://doi.org/10.1093/neuros/nyaa565
Neurosurgery Alvarez R, Mastorakos P et. al.

Jan 14th, 2021 - Retrobulbar hemangioblastomas involving the optic apparatus in patients with von Hippel-Lindau disease (VHL) are rare, with only 25 reported cases in the literature. To analyze the natural history of retrobulbar hemangioblastomas in a large cohort...

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Guidelines  1 results

Von Hippel-Lindau Disease (PDQ®)–Health Professional Version
https://www.cancer.gov/types/kidney/hp/renal-cell-carcinoma-genetics/vhl-syndrome?cid=eb_govdel
National Cancer Institute

Von Hippel-Lindau disease (VHL) is an autosomal dominant disease with a predisposition to multiple neoplasms. Germline pathogenic variants in the VHL gene predispose individuals to specific types of both benign and malignant tumors and cysts in ma...

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Clinicaltrials.gov  757 results

MK-6482 as a potential treatment for von Hippel-Lindau disease-associated clear cell re...
https://doi.org/10.1080/13543784.2021.1925248
Expert Opinion on Investigational Drugs; Hasanov E, Jonasch E

May 4th, 2021 - Von Hippel-Lindau (VHL) disease is an inherited autosomal dominant syndrome caused by a germline mutation and/or deletion of the VHL gene. Inappropriate hypoxia inducible factor (HIF) meditated transcription of proangiogenic and metabolic genes le...

Von Hippel-Lindau disease and rapidly progressing pheochromocytomas in siblings.
https://doi.org/10.1007/s10689-021-00252-2 10.1136/jmg.28.7.443 10.1007/BF03346370 10.1001/archopht.125.2.239 10.1002/humu.20385 10.1016/j.jpurol.2010.12.007 10.1016/S0300-2977(01)00165-6 10.1158/1078-0432.CCR-17-0547 10.1016/j.jpedsurg.2012.07.003 10.1016/j.juro.2010.06.102 10.1016/j.juro.2010.12.050 10.1210/js.2019-00225 10.1002/ajmg.a.33760
Familial Cancer; Fugaru I, Goudie C et. al.

Apr 20th, 2021 - Von Hippel-Lindau (VHL) disease is an autosomal dominant inherited condition with a predisposition to the development of a variety of tumors including pheochromocytomas. A number of cancer surveillance protocols for patients with VHL have been dev...

Impact of Pancreatic Neuroendocrine Tumor on Mortality in Patients with von Hippel-Lind...
https://doi.org/10.1016/j.eprac.2021.03.005
Endocrine Practice : Official Journal of the American Col... Arnon L, Halperin R et. al.

Mar 19th, 2021 - The main causes for morbidity and mortality in von Hippel-Lindau (VHL) disease are central nervous system hemangioblastoma and clear cell renal cell carcinoma, whereas the effect of VHL-related pancreatic neuroendocrine tumors (PNET) on patient ou...

Multiple Hepatic and Pulmonary Tumours Combined with Bilateral Adrenal Masses in a Youn...
https://doi.org/10.1053/j.gastro.2021.02.033
Gastroenterology Kolokotronis T, Reis H

Feb 21st, 2021 - Multiple Hepatic and Pulmonary Tumours Combined with Bilateral Adrenal Masses in a Young Female with von Hippel-Lindau Disease.|2021|Kolokotronis T,Reis H,|

Retrobulbar Hemangioblastomas in von Hippel-Lindau Disease: Clinical Course and Managem...
https://doi.org/10.1093/neuros/nyaa565
Neurosurgery Alvarez R, Mastorakos P et. al.

Jan 14th, 2021 - Retrobulbar hemangioblastomas involving the optic apparatus in patients with von Hippel-Lindau disease (VHL) are rare, with only 25 reported cases in the literature. To analyze the natural history of retrobulbar hemangioblastomas in a large cohort...

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News  9 results

Fast Five Quiz: Can You Correctly Identify the Various Aspects of Renal Cell Carcinoma?
https://reference.medscape.com/viewarticle/826053_2

Aug 5th, 2019 - Von Hippel-Lindau disease is an autosomal dominant syndrome that confers predisposition to various neoplasms. Renal cell carcinoma develops in nearly 40% of patients with von Hippel-Lindau disease and is a major cause of death among these patients...

What is your diagnosis? - July 2019
https://www.mdedge.com/gihepnews/article/203798/what-your-diagnosis-july-2019?channel=27662
Wai See Ma, MD, Hadi Moattar, MD, MBChB, PhD

Jun 28th, 2019 - The diagnosis von Hippel-Lindau disease The diagnosis is von Hippel-Lindau disease (VHL). Subsequent brain and renal magnetic resonance imaging showed features suggestive of a 5-mm right cerebellar hemangioblastoma and right renal cell carcinoma (.

Pazopanib is active against renal, other neoplasms of von Hippel-Lindau disease
https://www.mdedge.com/hematology-oncology/article/176202/renal-cell-carcinoma/pazopanib-active-against-renal-other
Susan London

Oct 2nd, 2018 - The oral, multitargeted tyrosine kinase inhibitor pazopanib (Votrient) is active and safe in patients with renal cell carcinoma and other neoplasms caused by von Hippel-Lindau disease, a phase 2 trial has found. Eric Jonasch, MD, and his coinvesti.

VHL Alliance Publishes Suggested VHL Surveillance Guidelines
https://www.mdedge.com/neurology/article/118235/rare-diseases/vhl-alliance-publishes-suggested-vhl-surveillance-guidelines

Nov 7th, 2016 - The VHL Alliance has published suggested surveillance guidelines approved by the VHLA Clinical Advisory Council regarding testing for individuals at risk for von Hippel-Lindau disease (VHL) who do not yet have symptoms or those who are known to ha.

Integrating Genetic Counseling Into an Oncology Practice Can Benefit High-Risk Families
https://www.onclive.com/publications/oncology-business-news/2014/february-2014/integrating-genetic-counseling-into-an-oncology-practice-can-benefit-high-risk-families

Feb 25th, 2014 - Ellen T. Matloff, MS, CGC Genetic counseling—including testing and risk assessment—is one of the most rapidly growing areas of oncology and has become the standard of care for patients with a personal and family history of breast, ovary, or colon ...

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Patient Education  1 results see all →