ALLMedicine™ Acquired Von Willebrand Syndrome Center
Research & Reviews 126 results
ASAIO Journal (American Society for Artificial Internal O... Sakatsume K, Akiyama M et. al.
Dec 31st, 2021 - Acquired von Willebrand syndrome (AVWS), characterized by reduced von Willebrand factor (VWF) large multimers, has recently been implicated as the principal mechanism underlying bleeding in patients implanted with left ventricular assist devices (...
Anesthesia and Analgesia; Mazzeffi M, Henderson R et. al.
Dec 15th, 2021 - Coagulopathic bleeding is common during adult extracorporeal membrane oxygenation (ECMO), and acquired von Willebrand syndrome is a contributing factor. We compared ECMO patient blood samples that were treated in vitro with recombinant von Willebr...
Transfusion Oyedeji O, Sheqwara J et. al.
Sep 28th, 2021 - Essential thrombocythemia (ET) is associated with increased risk of bleeding secondary to acquired von Willebrand syndrome (AVWS). Bleeding in ET requires urgent platelet reduction by cytoreductive therapy such as hydroxyurea or thrombocytapheresi...
Hematology/oncology Clinics of North America; Langer AL, Connell NT
Aug 16th, 2021 - Acquired von Willebrand syndrome can occur in the setting of myeloproliferative neoplasms; plasma cell dyscrasias and other lymphoproliferative disorders; autoimmune conditions; and causes of increased shear forces, such as aortic stenosis or othe...
Current Problems in Cardiology; Abdelmaseih R, Thakker R et. al.
Aug 14th, 2021 - Heyde's syndrome is a multisystem disorder describing the association between calcified aortic stenosis, gastrointestinal tract bleeding from arteriovenous malformations, and acquired von Willebrand syndrome. Several studies have reported an incre...
Guidelines 2 results
American Journal of Hematology; Nichols WL, Rick ME et. al.
May 6th, 2009 - Von Willebrand factor (VWF) mediates blood platelet adhesion and accumulation at sites of blood vessel injury, and also carries coagulation factor VIII (FVIII) that is important for generating procoagulant activity. Von Willebrand disease (VWD), t...
Haemophilia : the Official Journal of the World Federatio... Nichols WL, Hultin MB et. al.
Mar 5th, 2008 - von Willebrand disease (VWD) is a commonly encountered inherited bleeding disorder affecting both males and females, causing mucous membrane and skin bleeding symptoms, and bleeding with surgical or other haemostatic challenges. VWD may be disprop...
Clinicaltrials.gov 1 results
Sep 30th, 2011 - Patients with severe aortic stenosis often suffer from an acquired Von Willebrand syndrome by degeneration of the polymers during passage through the narrow valve leading to turbulences. After written consent and an extended anamnesis of existing ...
News 2 results
Dec 5th, 2020 - The Philadelphia chromosome—negative myeloproliferative neoplasms (MPNs) are clonal disorders characterized by common mutations, but with distinct clinical features, treatment considerations, and prognostic outlooks.1 Identification of the JAK2 (J...
Nov 6th, 2017 - Von Willebrand syndrome Von Willebrand syndrome is a deficiency or dysfunction of von Willebrand factor (vWF), a protein with binding sites for platelets, collagen, and factor VIII that “serves as a bridge between platelets and injury sites in ves.