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About 408 results

ALLMedicine™ Acquired Von Willebrand Syndrome Center

Research & Reviews  153 results

Successful use of lenalidomide to treat refractory acquired von Willebrand disease asso...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9530414
Annals of Hematology; Green A, Shen YP et. al.

Oct 5th, 2022 - Acquired von Willebrand syndrome (AVWS) is a rare hematologic disorder characterized by quantitative or qualitative defects of von Willebrand factor (vWF), a protein crucial for normal hemostasis. AVWS has been described in association with severa...

ADAMTS13 inhibition to treat acquired von Willebrand syndrome during mechanical circula...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9669188
Journal of Thrombosis and Haemostasis : JTH; Deconinck SJ, Nix C et. al.

Sep 22nd, 2022 - Acquired von Willebrand syndrome (aVWS) is common in patients with mechanical circulatory support (MCS) devices. In these patients, the high shear stress in the device leads to increased shear-induced proteolysis of von Willebrand factor (VWF) by ...

Perioperative diagnosis and impact of acquired von Willebrand syndrome in infants with ...
https://doi.org/10.1182/blood.2022015699
Blood Icheva V, Ebert J et. al.

Sep 3rd, 2022 - AVWS (acquired von Willebrand syndrome) has been reported in patients with congenital heart diseases (CHD) associated with shear stress caused by significant blood flow gradients. Its etiology and impact on intraoperative bleeding during pediatric...

Acquired von Willebrand syndrome: Five cases report and literature review.
https://doi.org/10.1016/j.thromres.2022.08.025
Thrombosis Research; Ghariani I, Braham N et. al.

Sep 2nd, 2022 - Acquired von Willebrand syndrome is a rare bleeding disorder with laboratory findings similar to those of inherited von Willebrand disease. Principal factors distinguishing acquired von Willebrand syndrome from the latter condition include lack of...

Acquired von Willebrand syndrome and lymphoid neoplasms: A review of malignancy managem...
https://doi.org/10.1111/hae.14648
Haemophilia : the Official Journal of the World Federatio... Nicol C, Pan-Petesch B et. al.

Aug 26th, 2022 - Acquired von Willebrand syndrome (AWS) is a rare and potentially life-threatening bleeding disorder. AWS is primarily associated with lymphocyte-related disorders (AWS-LRD), such as lymphoma and IgM monoclonal gammopathy of undetermined significan...

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Guidelines  2 results

Clinical and laboratory diagnosis of von Willebrand disease: a synopsis of the 2008 NHL...
https://doi.org/10.1002/ajh.21405
American Journal of Hematology; Nichols WL, Rick ME et. al.

May 6th, 2009 - Von Willebrand factor (VWF) mediates blood platelet adhesion and accumulation at sites of blood vessel injury, and also carries coagulation factor VIII (FVIII) that is important for generating procoagulant activity. Von Willebrand disease (VWD), t...

von Willebrand disease (VWD): evidence-based diagnosis and management guidelines, the N...
https://doi.org/10.1111/j.1365-2516.2007.01643.x
Haemophilia : the Official Journal of the World Federatio... Nichols WL, Hultin MB et. al.

Mar 5th, 2008 - von Willebrand disease (VWD) is a commonly encountered inherited bleeding disorder affecting both males and females, causing mucous membrane and skin bleeding symptoms, and bleeding with surgical or other haemostatic challenges. VWD may be disprop...

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Clinicaltrials.gov  4 results

The Ruxo-BEAT Trial in Patients With High-risk Polycythemia Vera or High-risk Essential Thrombocythemia
https://clinicaltrials.gov/ct2/show/NCT02577926

Oct 8th, 2020 - Polycythemia vera (PV) and essential thrombocythemia (ET) are classical Philadelphia-negative myeloproliferative neoplasms (MPN) that are characterized by an excess of cells in the peripheral blood, clonal bone marrow hyperplasia, and extramedulla...

Prognostic Value of Implementing VCE on Top in Constitutional VWD-patients With GI-bleeding
https://clinicaltrials.gov/ct2/show/NCT04466878

Jul 10th, 2020 - Inclusion criteria: Only constitutional VWD-patients fulfilling the inclusion criteria of the French reference center for VWD will be included. Patients with acquired von Willebrand syndrome will not be included. Material and Methods: A 15-items s...

Perioperative Modification of Hemostasis During Ventricular Assist Device Implantation
https://clinicaltrials.gov/ct2/show/NCT03966313

Apr 22nd, 2020 - Implanting a ventricular assist device (VAD) is a promising therapy for end-stage cardiac failure. However, the implantation of these devices is associated with a high risk of severe hemorrhages and massive blood product transfusion in the first 4...

Acquired Von Willebrand Syndrome in Severe Aortic Stenosis
https://clinicaltrials.gov/ct2/show/NCT00805051

Sep 30th, 2011 - Patients with severe aortic stenosis often suffer from an acquired Von Willebrand syndrome by degeneration of the polymers during passage through the narrow valve leading to turbulences. After written consent and an extended anamnesis of existing ...

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News  4 results

Cracking the “MGUS” Code Reveals Monoclonal Gammopathy of Clinical Significance:
https://www.onclive.com/view/cracking-the-mgus-code-reveals-monoclonal-gammopathy-of-clinical-significance-

Nov 1st, 2022 - When assessing monoclonal gammopathy it is important to rule out clinically significant associations requiring treatment. On initial patient consultation, gathering a detailed patient history and thorough physical exam can catch clinically signifi...

Treatment Armamentarium for Polycythemia Vera
https://www.onclive.com/view/treatment-armamentarium-for-polycythemia-vera

May 11th, 2022 - Transcript: Pankit Vachhani, MD: The management of polycythemia vera is a risk, takes a risk-adapted approach, whereby we categorize our patients at present in two categories, low-risk polycythemia vera and high-risk polycythemia vera. High-risk ...

JAK2 Mutations and JAK Inhibitors in the Management of Myeloproliferative Neoplasms
https://www.onclive.com/view/jak2-mutations-and-jak-inhibitors-in-the-management-of-myeloproliferative-neoplasms

Dec 5th, 2020 - The Philadelphia chromosome—negative myeloproliferative neoplasms (MPNs) are clonal disorders characterized by common mutations, but with distinct clinical features, treatment considerations, and prognostic outlooks.1 Identification of the JAK2 (J...

Teach your adolescent patients about normal menses, so they know when it’s abnormal
https://www.mdedge.com/familymedicine/article/151250/adolescent-medicine/teach-your-adolescent-patients-about-normal-menses/page/0/1
Pediatric News;

Nov 6th, 2017 - Von Willebrand syndrome Von Willebrand syndrome is a deficiency or dysfunction of von Willebrand factor (vWF), a protein with binding sites for platelets, collagen, and factor VIII that “serves as a bridge between platelets and injury sites in ves.

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