ALLMedicine™ Adenosine Deaminase 2 Deficiency Center
Research & Reviews 18 results
The Journal of Allergy and Clinical Immunology; Deuitch NT, Yang D et. al.
Nov 16th, 2021 - Deficiency of adenosine deaminase 2 (DADA2) is a recessively inherited autoinflammatory disorder caused by a loss of functional ADA2 protein. TNF inhibition (TNFi) has proven to be highly effective in treating inflammatory manifestations. We sough...
Blood Advances; Zoccolillo M, Brigida I et. al.
Aug 24th, 2021 - Adenosine deaminase 2 deficiency (DADA2) is a rare inherited disorder that is caused by autosomal recessive mutations in the ADA2 gene. Clinical manifestations include early-onset lacunar strokes, vasculitis/vasculopathy, systemic inflammation, im...
https://doi.org/10.1007/s10875-021-01121-4 10.1007/s10875-018-0525-8 10.1016/j.jaci.2019.12.908 10.1056/NEJMc1801927 10.1182/blood-2017-07-798660 10.1007/s10875-017-0449-8 10.1136/annrheumdis-2016-210802
Journal of Clinical Immunology; Yamashita M, Morio T
Aug 15th, 2021 - Another Exciting Data-HCT Successfully Cured Patients with DADA2 : A commentary on "Hematopoietic cell transplantation cures adenosine deaminase 2 deficiency: report on 30 patients" by Hashem H et al.|2021|Yamashita M,Morio T,|
Journal of Clinical Immunology; Hashem H, Bucciol G et. al.
Jul 30th, 2021 - Deficiency of adenosine deaminase 2 (DADA2) is an inherited inborn error of immunity, characterized by autoinflammation (recurrent fever), vasculopathy (livedo racemosa, polyarteritis nodosa, lacunar ischemic strokes, and intracranial hemorrhages)...
Journal of Pediatric Ophthalmology and Strabismus; Veryser E, Meyts I et. al.
Jul 22nd, 2021 - Deficiency of human adenosine deaminase 2 (DADA2) is an auto-inflammatory inborn error of immunity caused by biallelic deleterious mutations in the gene encoding ADA2. The purpose of this article is to raise awareness among ophthalmologists and pe...