ALLMedicine™ Adenosine Deaminase 2 Deficiency Center
Research & Reviews 20 results
Postgraduate Medicine; Springer JM, Byram K
Jun 17th, 2022 - Polyarteritis nodosa (PAN) is a primary form of vasculitis characterized by inflammation of primarily medium-sized arteries. Several key events have shaped the current spectrum of the disease including the separation of a subgroup with microscopic...
Expert Review of Clinical Immunology; Signa S, Dell'Orso G et. al.
May 17th, 2022 - Primary immune regulatory disorders encompass a range of clinical conditions caused by different defects of immune regulatory mechanisms, including systemic autoinflammatory diseases (AIDs). Allogeneic hematopoietic stem cell transplantation may b...
The Journal of Allergy and Clinical Immunology; Deuitch NT, Yang D et. al.
Nov 16th, 2021 - Deficiency of adenosine deaminase 2 (DADA2) is a recessively inherited autoinflammatory disorder caused by a loss of functional ADA2 protein. TNF inhibition (TNFi) has proven to be highly effective in treating inflammatory manifestations. We sough...
Blood Advances; Zoccolillo M, Brigida I et. al.
Aug 24th, 2021 - Adenosine deaminase 2 deficiency (DADA2) is a rare inherited disorder that is caused by autosomal recessive mutations in the ADA2 gene. Clinical manifestations include early-onset lacunar strokes, vasculitis/vasculopathy, systemic inflammation, im...
https://doi.org/10.1007/s10875-021-01121-4 10.1007/s10875-018-0525-8 10.1016/j.jaci.2019.12.908 10.1056/NEJMc1801927 10.1182/blood-2017-07-798660 10.1007/s10875-017-0449-8 10.1136/annrheumdis-2016-210802
Journal of Clinical Immunology; Yamashita M, Morio T
Aug 15th, 2021 - Another Exciting Data-HCT Successfully Cured Patients with DADA2 : A commentary on "Hematopoietic cell transplantation cures adenosine deaminase 2 deficiency: report on 30 patients" by Hashem H et al.|2021|Yamashita M,Morio T,|