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About 4,193 results

ALLMedicine™ Antiphospholipid Syndrome Center

Research & Reviews  1,553 results

Antineutrophil cytoplasmic antibody-associated vasculitis in presence of positive antip...
https://doi.org/10.1186/s13256-022-03256-3 10.1002/art.21704 10.1016/j.berh.2019.101463 10.1191/096120300675018039 10.1016/0002-9343(91)80088-4 10.1016/j.jaad.2006.09.028 10.1016/S0049-0172(95)80037-9 10.1136/ard.2004.034231 10.1182/blood.V84.9.2854.2854 10.1177/096120339600500523 10.1177/096120339600500506
Journal of Medical Case Reports; Akhlaghi Kalahroodi M, Loghman M et. al.

Jan 25th, 2022 - Antineutrophil cytoplasmic antibody-associated vasculitis is dominated by inflammatory occlusion of small vessels, causing tissue ischemia in various organs. This disorder has rarely been associated with vasculopathy, such as antiphospholipid synd...

Antiphospholipid antibodies and idiopathic infertility.
https://doi.org/10.1177/09612033221076735
Lupus Del Porto F, Ferrero S et. al.

Jan 25th, 2022 - The aim of our study was to evaluate obstetric outcome of women affected by idiopathic infertility showing persistently positive antiphospholipid antibodies (aPL). : From 2000 consecutive patients undergoing ART, we selected 151 (7.55%) clinical r...

Mitral valve replacement due to Libman-Sacks endocarditis: lower limb cellulitis as a r...
https://doi.org/10.1136/bcr-2021-246078
BMJ Case Reports; Sexton G, McLoughlin J et. al.

Jan 22nd, 2022 - A 56-year-old woman was admitted due to new ulceration and acute digital ischaemia on a background of chronic leg ulcers bilaterally. Vasculitis screening returned strongly positive lupus anticoagulant levels and elevated anticardiolipin antibodie...

Antiphospholipid syndrome with mesenteric vein thrombosis and hepatic nodular regenerat...
https://doi.org/10.1097/MD.0000000000028105
Medicine Han SH, Park KD et. al.

Jan 21st, 2022 - Hepatic nodular regenerative hyperplasia (NRH), a nonspecific change in the liver parenchyma, is very rare in children. Hepatic microvascular changes may be the cause, as these vascular changes are uncommon in children. Antiphospholipid syndrome (...

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Guidelines  4 results

First Latin American clinical practice guidelines for the treatment of systemic lupus e...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6225798
Annals of the Rheumatic Diseases; Pons-Estel BA, Bonfa E et. al.

Jul 27th, 2018 - Systemic lupus erythematosus (SLE), a complex and heterogeneous autoimmune disease, represents a significant challenge for both diagnosis and treatment. Patients with SLE in Latin America face special problems that should be considered when therap...

European evidence-based recommendations for diagnosis and treatment of paediatric antip...
https://doi.org/10.1136/annrheumdis-2016-211001
Annals of the Rheumatic Diseases; Groot N, de Graeff N et. al.

May 6th, 2017 - Antiphospholipid syndrome (APS) is rare in children, and evidence-based guidelines are sparse. Consequently, management is mostly based on observational studies and physician's experience, and treatment regimens differ widely. The Single Hub and A...

Practice Bulletin No. 132: Antiphospholipid syndrome.
https://doi.org/10.1097/01.AOG.0000423816.39542.0f
Obstetrics and Gynecology;

Nov 22nd, 2012 - Antiphospholipid syndrome (APS) is an autoimmune disorder defined by the presence of characteristic clinical features and specified levels of circulating antiphospholipid antibodies (Box 1 and Box 2). Diagnosis requires that at least one clinical ...

ACOG Practice Bulletin No. 118: antiphospholipid syndrome.
https://doi.org/10.1097/AOG.0b013e31820a61f9
Obstetrics and Gynecology;

Dec 22nd, 2010 - ACOG Practice Bulletin No. 118: antiphospholipid syndrome.|2010||

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Clinicaltrials.gov  30 results

Safety and Efficacy of Zanubrutinib in the Treatment of Antiphospholipid Syndrome With Secondary Thrombocytopenia
https://clinicaltrials.gov/ct2/show/NCT05199909

Jan 20th, 2022 - Antiphospholipid syndrome (APS) is a disease spectrum characterized by thrombosis and/or pathological pregnancy, and characterized by persistent antiphospholipid antibodies (APL) positive in laboratory examination. The incidence of thrombocytopeni...

Effectivity and Safety of Different Anticoagulants in Patients With Thromboembolic Antiphospholipid Syndrome
https://clinicaltrials.gov/ct2/show/NCT05195372

Jan 19th, 2022 - Antiphospholipid syndrome is a thrombophilic diathesis characterised by the occurrence of recurrent, unprovoked thromboembolic events (arterial, venous, microvascular) in combination with the presence of specific APS antibodies. A distinction is m...

Phenomics in Autoimmune and Inflammatory Diseases
https://clinicaltrials.gov/ct2/show/NCT02466217

Dec 13th, 2021 - The family of inflammatory/autoimmune systemic diseases (IAD) represents a large group of human diseases. For most if not all of these IAD, the pathophysiological processes or exact causes remain poorly understood. Progresses in molecular understa...

Impact of Antiphospholipid Antibodies on Thrombin Generation During Sars-CoV2 Infection (TACIT2 Study)
https://clinicaltrials.gov/ct2/show/NCT05128760

Nov 22nd, 2021 - Context: Until 70% of thrombotic event are reported during Sars-CoV2 infection. Antiphospholipid antibodies (aPL) tests are often positive. We aim to determine if aPL positivity is involved in thrombose of Sars-CoV2 infection investigating the eff...

Study of CRP, Ferritine and D-Dimer in Covid-19 Patients Admitted To Respiratory ICU in Assuit University Hospitals
https://clinicaltrials.gov/ct2/show/NCT05102695

Nov 5th, 2021 - Inflammatory markers are often elevated in patients with COVID-19, notably C-reactive protein (CRP), D-dimer, lactate dehydrogenase (LDH), IL-6and ferritin. Multiple prior studies have found correlations between various biomarkers and clinical out...

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News  88 results

Low Preconception Complement Levels Linked to Adverse Pregnancy Outcomes in Antiphospholipid Syndrome
https://www.medscape.com/viewarticle/960632

Oct 11th, 2021 - Low serum levels of two complement proteins are linked to worse pregnancy outcomes in women with antiphospholipid syndrome (APS), the results of a multicenter study appear to confirm. The study evaluated preconception complement levels in 260 preg...

FDA Approves First Oral Anticoagulant for Children
https://www.medscape.com/viewarticle/953535

Jun 22nd, 2021 - The US Food and Drug Administration (FDA) has approved dabigatran etexilate (Pradaxa) oral pellets for the treatment of venous thromboembolism (VTE) in children aged 3 months to less than 12 years. The drug is to be administered immediately after ...

Managing Diffuse Peripheral Ischemia in Antiphospholipid Syndrome: Anticoagulation, Immunosuppression, or Vasodilation?
https://www.medscape.com/viewarticle/948988

Apr 14th, 2021 - This article originally appeared on Hospital for Special Surgery's website. Case Report A 39-year-old man with a history of well-controlled type 1 diabetes (T1D) since childhood and migraine presented with 1 week of pain and cyanosis of the finger...

Managing Diffuse Peripheral Ischemia in Antiphospholipid Syndrome: Anticoagulation, Immunosuppression, or Vasodilation?
https://www.medscape.com/viewarticle/948988?src=sapfe

Apr 14th, 2021 - This article originally appeared on Hospital for Special Surgery's website. Case Report A 39-year-old man with a history of well-controlled type 1 diabetes (T1D) since childhood and migraine presented with 1 week of pain and cyanosis of the finger...

Hairy Cell Leukemia: A Review of Epidemiology and Disease Presentation
https://www.onclive.com/view/hairy-cell-leukemia-a-review-of-epidemiology-and-disease-presentation

Dec 5th, 2020 - Introduction Hairy cell leukemia (HCL) is a rare lymphoid malignancy.1 HCL accounts for only 2% of all lymphoid leukemias, with 600 to 800 new cases diagnosed in the United States each year.1,2 The name of the disease is attributed to the appeara...

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Patient Education  2 results see all →