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About 1,090 results

ALLMedicine™ Castleman Disease Center

Research & Reviews  414 results

Castleman Disease Misdiagnosed as Pancreatic Neuroendocrine Tumor by Fine Needle Aspira...
https://doi.org/10.1177/00031348221102606
The American Surgeon; Gou H, Fan J et. al.

May 12th, 2022 - Castleman disease (CD) is a lymphoproliferative disorder that rarely occurs in the pancreas. We reported a 46-year-old man was admitted to our hospital due to recurrent minor epigastric pain for 7 days. The abdominal enhanced CT showed irregular f...

The disease course of Castleman disease patients with fatal outcomes in the ACCELERATE ...
https://doi.org/10.1111/bjh.18214
British Journal of Haematology; Fajgenbaum DC, Pierson SK et. al.

May 5th, 2022 - Castleman disease (CD) describes a group of rare, potentially fatal lymphoproliferative disorders. To determine factors associated with mortality in CD, we analysed data from deceased patients in the ACCELERATE registry and compared them with matc...

Sirolimus in Previously Treated Idiopathic Multicentric Castleman Disease
https://clinicaltrials.gov/ct2/show/NCT03933904

Apr 22nd, 2022 - Human herpesvirus(HHV)-8-negative, idiopathic multicentric Castleman disease (iMCD) is a rare hematologic illness. Current therapeutic options are limited and provide benefit for only a subset of patients. Blockade of IL-6 signaling with siltuxima...

When idiopathic retroperitoneal fibrosis mimics Castleman disease: a challenging differ...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8990696
BMJ Case Reports; Covelli C, Carosi I et. al.

Apr 9th, 2022 - When idiopathic retroperitoneal fibrosis mimics Castleman disease: a challenging differential diagnosis.|2022|Covelli C,Carosi I,Graziano P,Ascani S,|diagnosis,diagnostic imaging,

Synchronous visceral Kaposi sarcoma and extracavitary primary effusion lymphoma in a pa...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8966535
BMJ Case Reports; Bradshaw S, Oertling E et. al.

Mar 31st, 2022 - While infection should always lead the differential when a patient with AIDS presents with fever, inflammatory and malignant aetiologies should also be considered. With profound immunocompromise, malignancies can develop as sequelae of viral oncog...

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Drugs  1 results see all →

Clinicaltrials.gov  5 results

Sirolimus in Previously Treated Idiopathic Multicentric Castleman Disease
https://clinicaltrials.gov/ct2/show/NCT03933904

Apr 22nd, 2022 - Human herpesvirus(HHV)-8-negative, idiopathic multicentric Castleman disease (iMCD) is a rare hematologic illness. Current therapeutic options are limited and provide benefit for only a subset of patients. Blockade of IL-6 signaling with siltuxima...

Molecular Basis of Langerhans and Non-Langerhans Cell Histiocytic Neoplasms and Castleman Disease
https://clinicaltrials.gov/ct2/show/NCT05028621

Jan 3rd, 2022 - The study team will examine genetic changes, also known as mutations, in the DNA of participants' blood, or if applicable, bone marrow specimen. These types of tests are increasingly used by doctors to improve the accuracy of diagnosis and make de...

International Registry for Patients With Castleman Disease
https://clinicaltrials.gov/ct2/show/NCT02817997

Aug 24th, 2021 - This project is supported by the Castleman Disease Collaborative Network. Visit the CDCN website at http://www.cdcn.org/accelerate to sign up for the ACCELERATE registry! The ACCELERATE patient registry will give patients and families the opportun...

Tocilizumab for KSHV-Associated Multicentric Castleman Disease
https://clinicaltrials.gov/ct2/show/NCT01441063

Oct 27th, 2020 - BACKGROUND: Kaposi sarcoma herpesvirus-associated multicentric Castleman disease (KSHVMCD) is a rare lymphoproliferative disorder that develops predominantly in human immunodeficiency deficiency virus (HIV) infected patients. Patients often have s...

Castleman Disease Collaborative Network Biobank
https://clinicaltrials.gov/ct2/show/NCT02871050

Jul 31st, 2018 - The CDCN proposes to establish a biobank and associated clinical data for Castleman disease. Tissue and fluid (blood and saliva) samples will be collected both prospectively and retrospectively. Blood or saliva samples may also be collected from r...

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News  14 results

Doxorubicin-pomalidomide combo shows promise for Kaposi sarcoma
https://www.mdedge.com/infectiousdisease/article/237118/hiv/doxorubicin-pomalidomide-combo-shows-promise-kaposi-sarcoma
Caleb Rans, PharmD

Mar 12th, 2021 - Liposomal doxorubicin (Dox) plus pomalidomide (Pom) was safe and active in heavily pretreated patients with Kaposi sarcoma, according to results from a phase 1/2 trial. Dr.

Teaching an Old Dog New Tricks: Repurposing Cancer Drugs to Combat COVID-19
https://www.onclive.com/view/teaching-an-old-dog-new-tricks-repurposing-cancer-drugs-to-combat-covid-19

Feb 5th, 2021 - In response to the novel coronavirus disease 2019 (COVID-19) pandemic, investigators around the world channeled their efforts into acquiring a better understanding of the virus so that they could rapidly identify any weapons that may be used in th...

New guidelines for idiopathic multicentric Castleman disease
https://www.mdedge.com/hematology-oncology/article/184660/related-issues/new-guidelines-idiopathic-multicentric-castleman-disease
Andrew D. Bowser

Oct 10th, 2018 - Photo from Penn Medicine David C. Fajgenbaum, MD The anti-IL-6 antibody siltuximab is central to first-line treatment of idiopathic multicentric Castleman disease (iMCD), according to new guidelines on iMCD published in Blood.

New guidelines frame treatment options for Castleman disease
https://www.mdedge.com/hematology-oncology/article/175993/patient-survivor-care/new-guidelines-frame-treatment-options
Andrew D. Bowser

Sep 28th, 2018 - The anti-interleukin-6 antibody siltuximab is central to first-line treatment of idiopathic multicentric Castleman disease (MCD), although adjuvant chemotherapy can be critical in severe cases, according to the first-ever consensus treatment guide.

Rare type of MCL mimics Castleman disease
https://www.mdedge.com/fedprac/article/148854/hematologic-malignancies/rare-type-mcl-mimics-castleman-disease
Andrew D. Bowser

Oct 6th, 2017 - A rare type of mantle cell lymphoma (MCL) has features that are similar to those of Castleman disease, according to a recent report based on three patient cases. Lymph node biopsies for these patients initially indicated histologic features consis.

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Patient Education  2 results see all →