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About 305 results

ALLMedicine™ Cerebral Cavernous Malformation Center

Research & Reviews  119 results

Circulating Plasma miRNA Homologs in Mice and Humans Reflect Familial Cerebral Cavernou...
https://doi.org/10.1007/s12975-022-01050-3 10.3171/2019.3.JNS181724 10.1038/gim.2014.97 10.1093/neuros/nyy108 10.1161/CIRCRESAHA.121.318174 10.1161/STROKEAHA.116.015713 10.1093/neuros/nyaa478 10.1038/jcbfm.2015.98 10.1002/jmri.25831 10.3171/2016.5.JNS16687 10.1016/j.ejca.2017.12.025 10.1007/s11357-020-00201-4 10.1182/blood-2018-06-856062 10.1084/jem.20171178 10.1038/nm.4169 10.1073/pnas.1000132107 10.1084/jem.20091258 10.1186/s13023-021-02009-7 10.1186/s40478-019-0789-0 10.1007/s40291-016-0221-4 10.1371/journal.pone.0139233 10.1007/s12031-017-0880-6 10.1016/j.coph.2010.05.009 10.1038/nature22075 10.1007/978-1-4939-6866-4_3 10.1002/bit.26791 10.1016/j.ebiom.2020.103145 10.1001/jamapediatrics.2017.3884 10.1371/journal.pcbi.1005752 10.1007/978-1-4939-1062-5_25 10.1371/journal.pone.0206239 10.1016/j.jbi.2011.05.002 10.1093/nar/gkt1166 10.1002/cpt.136 10.3969/j.issn.1673-5374.2012.14.004 10.1186/s13195-020-00735-x 10.1158/0008-5472.CAN-04-0496 10.1093/nar/29.9.e45 10.1080/14640749408401131 10.1080/01621459.1993.10476339 10.1186/1471-2105-7-85 10.1007/978-1-4939-7471-9_14 10.1186/s13637-017-0062-4 10.1161/CIRCRESAHA.118.312680 10.1007/s12975-017-0561-3 10.1007/s11306-012-0482-9 10.1016/j.ceb.2017.02.007 10.1016/j.semcancer.2019.07.009 10.2741/4443 10.1097/MOP.0000000000000812 10.1016/j.ajhg.2021.04.005 10.1007/s12975-019-00725-8 10.1093/neuros/nyy539 10.1038/nature17178 10.1038/onc.2011.174 10.1177/0022034520917058 10.1272/jnms.84.148 10.1074/jbc.M112.361295 10.2174/1381612823666170714151715 10.1038/nrd.2016.246 10.1016/j.ejphar.2015.03.021 10.1002/cpph.57 10.1007/s10456-020-09736-8 10.1038/s41374-018-0030-y 10.1007/s12253-017-0308-1 10.1159/000487326
Translational Stroke Research; Romanos SG, Srinath A et. al.

Jun 18th, 2022 - Patients with familial cerebral cavernous malformation (CCM) inherit germline loss of function mutations and are susceptible to progressive development of brain lesions and neurological sequelae during their lifetime. To date, no homologous circul...

The Symptomatic Cerebral Cavernous Malformation Trial of REC-994
https://clinicaltrials.gov/ct2/show/NCT05085561

Jun 15th, 2022 - This is a multi-center, randomized, double-blind, placebo-controlled study to investigate the safety, efficacy and pharmacokinetics of REC-994 (200 mg and 400 mg) compared to placebo in subjects with symptomatic cerebral cavernous malformation (CCM).

Cerebral cavernous malformation development in chronic mouse models driven by dual reco...
https://doi.org/10.1177/0271678X221105995
Journal of Cerebral Blood Flow and Metabolism : Official ... Yang X, Dai Z et. al.

Jun 11th, 2022 - Cerebral cavernous malformation (CCM) is a brain vascular disease which can cause stroke, cerebral hemorrhage and neurological deficits in affected individuals. Loss-of-function mutations in three genes (CCM1, CCM2 and CCM3) cause CCM disease. Mul...

CoHOrt of Cerebral CavernOus maLformATion: multicEnter Prospective Observational Study
https://clinicaltrials.gov/ct2/show/NCT02946866

May 12th, 2022 - Cerebral cavernous malformation Patients with newly diagnosed, cerebral cavernous malformation who will visit one of the study centers during the period from June 2016 to December 2017. Patients would be eligible for enrollment if they were 18 yea...

Multiple spinal intramedullary cavernous angiomas with bleeding episode mimicking an in...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9063836
Journal of Radiology Case Reports; Utomo SA, Bajamal AH et. al.

May 10th, 2022 - Intramedullary cavernous angioma is a rare vascular malformation compared to cerebral cavernous malformation. The incidence of cavernous angioma is about 3 - 5% of all central nervous system lesions, 5 - 12% of all spinal vascular lesions, and 1% ...

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Clinicaltrials.gov  2 results

The Symptomatic Cerebral Cavernous Malformation Trial of REC-994
https://clinicaltrials.gov/ct2/show/NCT05085561

Jun 15th, 2022 - This is a multi-center, randomized, double-blind, placebo-controlled study to investigate the safety, efficacy and pharmacokinetics of REC-994 (200 mg and 400 mg) compared to placebo in subjects with symptomatic cerebral cavernous malformation (CCM).

CoHOrt of Cerebral CavernOus maLformATion: multicEnter Prospective Observational Study
https://clinicaltrials.gov/ct2/show/NCT02946866

May 12th, 2022 - Cerebral cavernous malformation Patients with newly diagnosed, cerebral cavernous malformation who will visit one of the study centers during the period from June 2016 to December 2017. Patients would be eligible for enrollment if they were 18 yea...

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Patient Education  1 results

Cavernous Malformations
https://www.hopkinsmedicine.org/health/conditions-and-diseases/cavernous-malformations

A cerebral cavernous malformation (CCM) is a collection of small blood vessels (capillaries) in the central nervous system that is enlarged and irregular in structure. In CCM, the walls of the capillaries are thinner than normal, less elastic, and...

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