ALLMedicine™ Dysfibrinogenemia Center

May 5th, 2022 - Reference Range Thrombin time is a screening coagulation test designed to assess fibrin formation from fibrinogen in plasma. The reference range for the thrombin time is usually less than 20 seconds (ie, 15-19 seconds), but this depends on the tes...

May 5th, 2022 - Thrombin time is a screening coagulation test designed to assess fibrin formation from fibrinogen in plasma. The reference range for the thrombin time is usually less than 20 seconds (ie, 15-19 seconds), but this depends on the test kit/instrument...

Apr 28th, 2022 - Practice Essentials Dysfibrinogenemia is a rare coagulation disorder resulting from an abnormal or decreaased level of fibrinogen, which is a 340 kDa glycoprotein produced in the liver, necessary to form blood clots and control bleeding. Dysfibrin...

Apr 28th, 2022 - History In congenital dysfibrinogenemia, bleeding is usually mild and may not manifest until after surgical procedures or major traumatic events. Rarely, however, patients can experience combined hemorrhagic and thrombotic tendencies. In female pa...

Apr 28th, 2022 - Practice Essentials Dysfibrinogenemia is a rare coagulation disorder resulting from an abnormal or decreaased level of fibrinogen, which is a 340 kDa glycoprotein produced in the liver, necessary to form blood clots and control bleeding. Dysfibrin...

Feb 10th, 2022 - Hereditary dysfibrinogenemia results from monoallelic mutation in one of the fibrinogen genes (FGA, FGB, FGG). The spectrum of molecular abnormalities is broad, leading to several subtypes of coagulation disorders with specific biological and clin...

Nov 4th, 2019 - Major hemorrhage in the setting of severe trauma patient is associated with significant morbidity and mortality. Hemorrhage is compounded by trauma induced coagulopathy of which hypo/dysfibrinogenemia and hypoperfusion play a significant role. The...

Dec 3rd, 2018 - Nephrotic syndrome is one of several disease states that increase a patient's risk of developing VTE. VTE associated with nephrotic syndrome appears to be due to a hypercoagulable state resulting from urinary loss of anticoagulant proteins, togeth...