About 355 results

ALLMedicine™ Evans Syndrome Center

Research & Reviews  137 results

Concurrent severe pulmonary tuberculosis with Evans syndrome: a case report with litera...
https://doi.org/10.1186/s12879-022-07512-1 10.1128/microbiolspec.TNMI7-0004-2016 10.1016/j.it.2016.09.007 10.5811/cpcem.2019.1.41028 10.1182/asheducation-2018.1.382 10.3390/jcm9123851 10.2147/JBM.S176144 10.3389/fpubh.2021.728768 10.1191/0961203306lu2262xx 10.3389/fimmu.2021.676132 10.1002/ccr3.4113
BMC Infectious Diseases; Pan XH, Xu JK et. al.

Jun 13th, 2022 - Tuberculosis is a bacterial infection involving multiple organs and systems. Its hematological presentation mainly includes anemia and leukocytosis. Evans syndrome is a rare autoimmune disease characterized by autoimmune hemolytic anemia, immune t...

Determinants of splenectomy long-term outcomes in pediatric autoimmune cytopenias.
Blood Pincez T, Aladjidi N et. al.

Apr 21st, 2022 - Splenectomy is effective in ~70-80% of pediatric chronic immune thrombocytopenia (cITP) and few data exist in autoimmune hemolytic anemia (AIHA) and Evans syndrome (ES). Because of the irreversibility of the procedure and the lack of predictor of ...

Complete recovery of deep venous thrombosis from Coombs (+) thrombotic thrombocytopenic...
Journal of Cardiothoracic Surgery; Zhou M, Yin J

Mar 23rd, 2022 - Acute thrombotic thrombocytopenic purpura (TTP) is an aggressive thrombotic microangiopathy that if not treated, can have a 90% mortality rate. Timely, extensive plasma exchange (PEX) has been indicated to reduce the mortality rate to < 10%, but i...

Adult Evans' Syndrome.
Hematology/oncology Clinics of North America; Michel M

Mar 15th, 2022 - Evans syndrome (ES) is a rare immune disorder defined as the simultaneous or sequential occurrence in a single patient of immune thrombocytopenia (ITP) and warm autoimmune hemolytic anemia (wAIHA) ± autoimmune neutropenia (AIN). ES represents appr...

Hemolytic Anemia Workup

Feb 19th, 2022 - Approach Considerations Standard blood studies for the workup of suspected hemolytic anemia include the following: Complete blood cell count Peripheral blood smear Serum lactate dehydrogenase (LDH) Serum haptoglobin Indirect bilirubin Hemolysis of...

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News  5 results

BTK Inhibitor Shows Potential in Immune Thrombocytopenia

Apr 13th, 2022 - An investigational oral Bruton's tyrosine kinase (BTK) inhibitor was tolerable and yielded rapid and durable responses in pretreated patients with immune thrombocytopenia (ITP), according to results of an open-label phase I/II trial. In the 60-pat...

Expert Outlines Clinical Implications of Precision Medicine in GI Cancers

Dec 4th, 2020 - Shirley Michelle Shiller, DO Regarding precision medicine in gastrointestinal (GI) cancers, pathologists are working to determine which patient populations should undergo which molecular tests. Colorectal Cancer In a presentation during the 201...

Tylosis in a Patient With Howel-Evans Syndrome: Management With Acitretin
Sabra M. Abner, MD, Audra Isaac, MD et. al.

Nov 4th, 2020 - To the Editor: Tylosis with esophageal cancer was first described by Howel-Evans et al1 in 1958 in a family from Liverpool, England. The disease is inherited in an autosomal-dominant fashion with a mutation in the tylosis with esophageal cancer ge.

ASH: Genes affecting risk, severity of chronic ITP are identified
Mary Jo Dales

Dec 6th, 2015 - ORLANDO – Children with chronic immune thrombocytopenia (ITP) have an increased frequency of damaging variants in genes associated with cellular immunity, notably IFNA17 and IFNLR1, based on the results of whole genome sequencing. The links to IFN.

Immunosuppressant can treat autoimmune cytopenias
HT Staff

Oct 27th, 2015 - Red and white blood cells New research suggests the immunosuppressant sirolimus may be a promising treatment option for patients with refractory autoimmune cytopenias. The drug proved particularly effective in children with autoimmune lymphoprolif.

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