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About 198 results

ALLMedicine™ Factor XI Deficiency Center

Research & Reviews  77 results

Abnormal (Dysfunctional) Uterine Bleeding Workup
http://emedicine.medscape.com/article/257007-workup

Mar 29th, 2022 - Laboratory Studies Laboratory studies for patients with abnormal uterine bleeding (AUB) may include human chorionic gonadotropin (HCG), complete blood count (CBC), Pap smear, endometrial sampling, thyroid functions and prolactin, liver functions, ...

Report of surgeries, their outcome and the thrombin generation assay in patients with F...
https://doi.org/10.1111/hae.14506
Haemophilia : the Official Journal of the World Federatio... Désage S, Dargaud Y et. al.

Feb 6th, 2022 - In patients with FXI deficiency, the risk of surgery-related bleeding is poorly correlated with plasma FXI activity (FXI:C); the latter can therefore not be used as a reliable predictor of bleeding in surgeries. The aim of this retrospective study...

Pediatric severe factor XI deficiency: A multicenter study.
https://doi.org/10.1002/pbc.29545
Pediatric Blood & Cancer; Barg AA, Levy-Mendelovich S et. al.

Dec 28th, 2021 - Factor XI (FXI) deficiency is a rare autosomal recessive bleeding disorder. Only scarce publications address its clinical features in children. The increased prevalence of FXI deficiency in Israel enabled data collection for this large multicenter...

Genetic analysis of compound heterozygous pathogenic variants of the F11 gene in two Ch...
https://doi.org/10.1097/MBC.0000000000001105
Blood Coagulation & Fibrinolysis : an International Journ... Wang H, Jiang S et. al.

Nov 21st, 2021 - The aim of this study was to explore the molecular pathogenesis of two families with compound heterozygous hereditary factor XI deficiency. All the exons, flanking sequences, 5' and 3' untranslated regions of the F11 gene were analysed by direct D...

Phenotype and genotype analysis of patients with severe factor XI deficiency in Shaanxi...
https://doi.org/10.1097/MBC.0000000000001061
Blood Coagulation & Fibrinolysis : an International Journ... Yuan L, Chen W et. al.

Nov 16th, 2021 - Congenital coagulation factor XI (FXI) deficiency is a rare bleeding disorder with a heterogeneous haemorrhagic phenotype and various hotspot gene mutations associated with race and geography. Studies on FXI deficiency in Shaanxi Province, China, ...

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Clinicaltrials.gov  1 results

HEMOLEVEN® Expanded Access Program Prevention of Surgical/Postpartum Hemorrhage Severe Inherited Factor XI Deficiency
https://clinicaltrials.gov/ct2/show/NCT01701947

Aug 23rd, 2013 - Many patients are asymptomatic until hemostatically challenged by surgery or trauma; so, the diagnosis is often made in late childhood or early adulthood but always after full liver maturation (i.e. 6 months) as reported by Andrew et al. Spontaneo...

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News  1 results

FDA OKs First Direct-to-Consumer Genetic Risk Tests
https://www.medscape.com/viewarticle/878287

Apr 6th, 2017 - In the latest step toward personalized medicine, the US Food and Drug Administration (FDA) today approved the first direct-to-consumer (DTC) genetic tests that provide information on a person's risk of developing a disease. The tests in question, ...

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