ALLMedicine™ Glanzmann Thrombasthenia Center

May 17th, 2022 - Reference Range Normal clot retraction time is 0-2 hours. If the weight of the clot or the percent of extruded serum is used as the end measure, the result depends on the volume of the specimen used, which varies from laboratory to laboratory. [1]...

May 17th, 2022 - Reference Range Normal clot retraction time is 0-2 hours. If the weight of the clot or the percent of extruded serum is used as the end measure, the result depends on the volume of the specimen used, which varies from laboratory to laboratory. [1]...

May 17th, 2022 - Normal clot retraction time is 0-2 hours. If the weight of the clot or the percent of extruded serum is used as the end measure, the result depends on the volume of the specimen used, which varies from laboratory to laboratory.[1] The coagulation ...

Apr 13th, 2022 - Frequent and severe bleeding events (SBE) in patients with inherited qualitative platelet disorders Bernard-Soulier Syndrome (BSS) and Glanzmann Thrombasthenia (GT) can lead to secondary iron deficiency anemia (IDA). SBE are primarily treated with...

Mar 15th, 2022 - Glanzmann thrombasthenia (GT) is a rare inherited platelet function disorder caused by a quantitative and/or qualitative defect of the αIIbβ3 integrin. Pregnancy and delivery are recognized risk periods for bleeding in women with GT. The newborn m...

Apr 17th, 2019 - Little is known of the molecular basis of disorders of signalling pathways potentially responsible of constitutional defects of platelet functions (adhesion, aggregation or secretion) (1-5). Indeed, in routine practice, this investigation is limit...

Jan 9th, 2019 - Isolated communities in the Canadian province of Newfoundland and Labrador have an “unusual prevalence” of certain hereditary bleeding disorders, a fact attributable to the province’s unique topography and settlement patterns, according to a new s.

Nov 6th, 2017 - Von Willebrand syndrome Von Willebrand syndrome is a deficiency or dysfunction of von Willebrand factor (vWF), a protein with binding sites for platelets, collagen, and factor VIII that “serves as a bridge between platelets and injury sites in ves.

Jun 26th, 2015 - VIENNA – Inherited platelet function disorders are associated with a significant bleeding risk during surgery, a retrospective, multicenter study shows. “The frequency of excessive bleeding assessed by one of three criteria at surgery is pretty re.

Apr 16th, 2015 - Genetic analysis Photo courtesy of NIGMS A study of genes associated with bleeding disorders suggests it can be challenging to gauge the clinical significance of novel gene variants. Researchers analyzed genomic data from more than 16,000 subjects.

Apr 21st, 2006 - Action Points Explain to interested patients that Glanzmann thrombasthenia is a rare genetic blood disease in which the glycoprotein IIb/IIIa (GP IIb/IIIa) complex is either deficient or dysfunctional, resulting in defective platelet aggregation. ...