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About 2,973 results

ALLMedicine™ Granulomatosis With Polyangiitis Center

Research & Reviews  1,055 results

Posterior reversible encephalopathy syndrome after first rituximab transfusion for trea...
https://doi.org/10.1136/bcr-2022-248864
BMJ Case Reports; Gong Y, Lam A et. al.

May 14th, 2022 - A woman in her 60s developed acute onset headache, blurry vision and encephalopathy a few hours after rituximab infusion, given to treat granulomatosis with polyangiitis. CT scan showed oedema in the posterior circulation area suggesting the diagn...

Profile of circulating extracellular vesicles microRNA correlates with the disease acti...
https://doi.org/10.1093/cei/uxac022
Clinical and Experimental Immunology; Surmiak M, Wawrzycka-Adamczyk K et. al.

May 14th, 2022 - Granulomatosis with polyangiitis is a chronic systemic inflammation of small vessels characterized by circulating anti-proteinase 3 antibodies. MicroRNAs are short transcripts specifically inhibiting protein translation. Neutrophils can release ex...

Studies of the Natural History, Pathogenesis, and Outcome of Idiopathic Systemic Vasculitis
https://clinicaltrials.gov/ct2/show/NCT02257866

May 13th, 2022 - The purpose of this protocol is to study the natural history of idiopathic systemic vasculitis in children and adults. The idiopathic vasculitides are a group of rare, systemic diseases involving inflammation of arteries and other tissue with resu...

The use of ECMO in pediatric granulomatosis with polyangiitis.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9092879
Pediatric Rheumatology Online Journal; Finkel R, Honig J et. al.

May 11th, 2022 - Granulomatosis with polyangiitis (GPA) vasculitis with pulmonary-renal syndrome rarely presents in children and is associated with high mortality rates. We present the case of a 13-year-old male with newly diagnosed GPA vasculitis, treated with ex...

Pyoderma Gangrenosum-like Skin Ulceration in ANCA-associated vasculitis: A Retrospectiv...
https://doi.org/10.1111/ced.15251
Clinical and Experimental Dermatology; Shakshouk H, Gibson LE

May 8th, 2022 - ANCA-associated vasculitis (AAV) can be associated with various cutaneous manifestations. Several case reports have described skin ulceration resembling pyoderma gangrenosum (PG), particularly in granulomatosis with polyangiitis (GPA), however, th...

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Guidelines  4 results

2022 American College of Rheumatology/European Alliance of Associations for Rheumatolog...
https://doi.org/10.1002/art.41982
Arthritis & Rheumatology (Hoboken, N.J.); Grayson PC, Ponte C et. al.

Feb 3rd, 2022 - To develop and validate revised classification criteria for eosinophilic granulomatosis with polyangiitis (EGPA). Patients with vasculitis or comparator diseases were recruited into an international cohort. The study proceeded in 5 phases: 1) iden...

2022 American College of Rheumatology/European Alliance of Associations for Rheumatolog...
https://doi.org/10.1002/art.41986
Arthritis & Rheumatology (Hoboken, N.J.); Robson JC, Grayson PC et. al.

Feb 3rd, 2022 - To develop and validate revised classification criteria for granulomatosis with polyangiitis (GPA). Patients with vasculitis or comparator diseases were recruited into an international cohort. The study proceeded in 5 phases: 1) identification of ...

2021 American College of Rheumatology/Vasculitis Foundation Guideline for the Managemen...
https://doi.org/10.1002/art.41773
Arthritis & Rheumatology (Hoboken, N.J.); Chung SA, Langford CA et. al.

Jul 9th, 2021 - To provide evidence-based recommendations and expert guidance for the management of antineutrophil cytoplasmic antibody-associated vasculitis (AAV), including granulomatosis with polyangiitis (GPA), microscopic polyangiitis (MPA), and eosinophilic...

Consensus statement on surgical pathology of the aorta from the Society for Cardiovascu...
https://doi.org/10.1016/j.carpath.2015.05.001
Cardiovascular Pathology : the Official Journal of the So... Stone JR, Bruneval P et. al.

Jun 9th, 2015 - Inflammatory diseases of the aorta include routine atherosclerosis, aortitis, periaortitis, and atherosclerosis with excessive inflammatory responses, such as inflammatory atherosclerotic aneurysms. The nomenclature and histologic features of thes...

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Drugs  7 results see all →

Clinicaltrials.gov  18 results

Studies of the Natural History, Pathogenesis, and Outcome of Idiopathic Systemic Vasculitis
https://clinicaltrials.gov/ct2/show/NCT02257866

May 13th, 2022 - The purpose of this protocol is to study the natural history of idiopathic systemic vasculitis in children and adults. The idiopathic vasculitides are a group of rare, systemic diseases involving inflammation of arteries and other tissue with resu...

Long-term Access Program (LAP) of Mepolizumab for Subjects Who Participated in Study MEA115921
https://clinicaltrials.gov/ct2/show/NCT03298061

Apr 11th, 2022 - Eosinophilic Granulomatosis with Polyangiitis (EGPA), also referred to as Churg-Strauss syndrome, is a rare hyper-eosinophilic syndrome. Eosinophilia is central to the pathophysiology of EGPA and interleukin-5 (IL-5) is a key cytokine regulating t...

Hydroxychloroquine in ANCA Vasculitis Evaluation
https://clinicaltrials.gov/ct2/show/NCT04316494

Mar 18th, 2022 - This is a multi-centre, randomised, placebo-controlled, double-blind study to evaluate if hydroxychloroquine in combination with background maintenance therapy improves the clinical response and quality of life in patients with AAV. 76 participant...

Maintenance of Remission With Rituximab Versus Azathioprine for Newly-diagnosed or Relapsing Eosinophilic Granulomatosis With Polyangiitis.
https://clinicaltrials.gov/ct2/show/NCT03164473

Feb 10th, 2022 - Rituximab, an anti-CD20 monoclonal antibody, has been shown to be as effective as cyclophosphamide to induce GPA and MPA remission, with an acceptable safety profile, leading to its registration by the FDA and EMA as remission-induction therapy in...

The Assessment of Prednisone In Remission Trial - Centers of Excellence Approach
https://clinicaltrials.gov/ct2/show/NCT01940094

Jan 27th, 2022 - Patients with granulomatosis with polyangiitis (GPA, Wegener's) will be recruited at one of the Vasculitis Centers of Excellence. Participants will be randomized 1:1 either to taper their prednisone dose down to 5 mg/day according to a standardize...

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News  97 results

Plasma Exchange Works for ANCA-Associated Vasculitis
https://www.medscape.com/viewarticle/969671

Mar 8th, 2022 - NEW YORK (Reuters Health) - Plasma exchange can be an effective treatment for anti-neutrophil cytoplasm antibody (ANCA)-associated vasculitis (AAV), according to an updated systematic review and meta-analysis. Granulomatosis with polyangiitis and ...

FDA Approves Rituximab for Multiple Pediatric Cancers
https://www.medscape.com/viewarticle/964124

Dec 3rd, 2021 - The US Food and Drug Administration yesterday approved rituximab (Rituxan) in combination with chemotherapy for pediatric patients (age 6 months to <18 years) with previously untreated, advanced stage, CD20-positive diffuse large B-cell lymphoma (...

Rituximab, Cyclophosphamide Similar for Inducing EGPA Remission
https://www.medscape.com/viewarticle/963134

Nov 17th, 2021 - Rituximab didn't perform any worse or better at inducing remission after a year in patients with eosinophilic granulomatosis with polyangiitis (EGPA) than did conventional treatment with cyclophosphamide in the phase 3 REOVAS trial conducted in Fr...

For EGPA vasculitis, rituximab comparable with cyclophosphamide for inducing remission
https://www.mdedge.com/rheumatology/article/248697/lupus-connective-tissue-diseases/egpa-vasculitis-rituximab-comparable
Richard Mark Kirkner

Nov 15th, 2021 - Rituximab didn’t perform any worse or better at inducing remission after a year in patients with eosinophilic granulomatosis with polyangiitis (EGPA) than did conventional treatment with cyclophosphamide in the phase 3 REOVAS trial conducted in Fr.

New ACR Guidelines Give Advice on Six Forms of Vasculitis
https://www.medscape.com/viewarticle/954873

Jul 15th, 2021 - Three new guidelines from the American College of Rheumatology, in partnership with the Vasculitis Foundation, offer evidence-based recommendations for managing and treating six different forms of systemic vasculitis. Dr Sharon Chung "It's not unu...

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Patient Education  8 results see all →