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About 615 results

ALLMedicine™ Hypofibrinogenemia Center

Research & Reviews  218 results

Viscoelastic Testing and Factor Concentrate Therapy to Reduce Bleeding and Transfusions...
https://doi.org/10.1213/XAA.0000000000001594
A&A Practice; Sarmiento IA, Brenner AC et. al.

Jun 23rd, 2022 - The surgical procedure to separate conjoined twins represents a rare and major challenge. One of the most feared perioperative scenarios is the presence of coagulopathy secondary to bleeding. We present a case of the surgical separation of ischiop...

Efficacy and safety of fibrinogen administration in acute post-traumatic hypofibrinogen...
https://doi.org/10.1016/j.jocn.2022.05.016
Journal of Clinical Neuroscience : Official Journal of Th... Sabouri M, Vahidian M et. al.

Jun 2nd, 2022 - This study was conducted to evaluate clinical outcomes after fibrinogen administration in hypofibrinogenemia following severe traumatic brain injury. Post traumatic coagulopathy (PTC) is a common but devastating medical condition in patients with ...

Prospective Cohort for Adult Hemophagocytosis
https://clinicaltrials.gov/ct2/show/NCT03117010

May 9th, 2022 - Study process is as follows. Informed consent for subjects fulfilling the inclusion criteria. Laboratory evaluation will be done for subjects according to the following diagnostic criteria. Diagnosis will be established if one of either 1 or 2 bel...

Thrombin Time
https://emedicine.medscape.com/article/2086278-print

May 5th, 2022 - Thrombin time is a screening coagulation test designed to assess fibrin formation from fibrinogen in plasma. The reference range for the thrombin time is usually less than 20 seconds (ie, 15-19 seconds), but this depends on the test kit/instrument...

Thrombin Time
http://emedicine.medscape.com/article/2086278-overview

May 5th, 2022 - Reference Range Thrombin time is a screening coagulation test designed to assess fibrin formation from fibrinogen in plasma. The reference range for the thrombin time is usually less than 20 seconds (ie, 15-19 seconds), but this depends on the tes...

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Drugs  6 results see all →

Clinicaltrials.gov  19 results

Prospective Cohort for Adult Hemophagocytosis
https://clinicaltrials.gov/ct2/show/NCT03117010

May 9th, 2022 - Study process is as follows. Informed consent for subjects fulfilling the inclusion criteria. Laboratory evaluation will be done for subjects according to the following diagnostic criteria. Diagnosis will be established if one of either 1 or 2 bel...

Fibrinogen Replacement to Prevent Intracranial Haemorrhage in Ischemic Stroke Patients After Thrombolysis (FibER)
https://clinicaltrials.gov/ct2/show/NCT05300672

Mar 29th, 2022 - Intravenous recombinant tissue plasminogen activator (rtPA) is the first recommended reperfusion therapy for acute ischemic stroke, as well as endovascular treatment in case of large vessel occlusion, but it increases the risk of ICH. The pathophy...

Safety and Efficacy of Fibryga in Congenital Fibrinogen Deficiency
https://clinicaltrials.gov/ct2/show/NCT03793426

Feb 17th, 2022 - There is a need to increase the body of data on treatment effectiveness and safety in the ultra-rare setting of congenital fibrinogen deficiency. Real-world evidence (RWE) derived from non-interventional studies can describe product utilization, d...

Administration of Prothrombin Complex Concentrate vs. Standard Transfusion During/After Heart Transplantation
https://clinicaltrials.gov/ct2/show/NCT03341156

Jan 11th, 2022 - This study will be a randomized (1:1; PCC vs. plasma), open-label trial of hemostatic therapies during heart transplantation. The goal is to enroll 60 patients. Informed consent will be obtained from patients meeting the inclusion and exclusion cr...

Comparison of Fibrinogen Concentrate and Cryoprecipitate in Pediatric Cardiac Surgery Patients
https://clinicaltrials.gov/ct2/show/NCT04376762

Oct 28th, 2021 - Once the need for fibrinogen supplementation is confirmed, study participants will be randomized into one of two treatment groups (n=15 in each group): Cryoprecipitate group (dose: 10 ml/kg; active control group) or Fibrinogen Concentrate group (d...

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News  3 results

Fast Five Quiz: Hemophagocytic Lymphohistiocytosis Presentation and Diagnosis
https://reference.staging.medscape.com/viewarticle/932048_2

Jun 16th, 2020 - Figure 1. Hemophagocytosis in the bone marrow. The diagnosis of HLH is based on clinical criteria. Diagnostic criteria that were developed by the Histiocyte Society for HLH (HLH-2004 criteria) are the most commonly used. They include: Fever: ≥ 7 d...

COVID-19 and the Slippery Road of Cytokine Storms
https://www.medpagetoday.com/infectiousdisease/covid19/86021

Apr 19th, 2020 - Early reports on the COVID-19 pandemic allude to a cytokine storm or hyper-inflammation, especially in patients who succumbed to the illness. These conclusions are based on elevated levels of ferritin and other inflammatory markers, drawing compar...

Fibrinogen concentrate effective, safe for postop bleeding
https://www.mdedge.com/hematology-oncology/article/210940/bleeding-disorders/fibrinogen-concentrate-effective-safe-postop
Neil Osterweil

Oct 25th, 2019 - SAN ANTONIO – Fibrinogen concentrate was noninferior to cryoprecipitate for controlling bleeding following cardiac surgery in the randomized FIBRES trial, Canadian investigators reported. Neil Osterweil/MDedge News Dr.

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