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About 2,153 results

ALLMedicine™ Kaposi Sarcoma Center

Research & Reviews  774 results

Leiomyosarcoma of the Penis: A Case Report and Re-Appraisal
https://www.mdedge.com/fedprac/article/254639/oncology/leiomyosarcoma-penis-case-report-and-re-appraisal
Zainub Ajmal, MBBS, Abdul Moiz Khan, MBBS et. al.

May 16th, 2022 - Penile cancer is rare with a worldwide incidence of 0. 8 cases per 100,000 men.

CDK4/6 inhibitors sensitize gammaherpesvirus-infected tumor cells to T-cell killing by ...
https://doi.org/10.1186/s12967-022-03400-z 10.1097/QAD.0000000000000808 10.3389/fonc.2019.00713 10.3389/fmicb.2012.00066 10.1128/JVI.74.11.5300-5309.2000 10.1016/S1074-7613(00)00036-4 10.1073/pnas.140129797 10.1128/JVI.07216-11 10.1182/blood.V90.6.2390 10.4049/jimmunol.0803218 10.1084/jem.20070256 10.1371/journal.ppat.1000255 10.1006/viro.2002.1716 10.1182/blood-2004-05-1798 10.1038/s41467-018-05506-9 10.1128/JVI.05923-11 10.1038/35041064 10.1073/pnas.1202637109 10.1038/nrclinonc.2016.26 10.1007/s40265-020-01461-2 10.1158/2159-8290.CD-17-0915 10.1038/nature23465 10.1016/j.celrep.2018.02.053 10.18632/oncotarget.17960 10.1080/2162402X.2018.1546544 10.1371/journal.ppat.1009091 10.1158/1078-0432.CCR-18-1256 10.1016/S0065-230X(06)97004-3 10.1101/gad.13.12.1501 10.1016/j.semcancer.2009.02.010 10.1073/pnas.1503806112 10.1093/jnci/dji113 10.1038/s41577-020-0300-y 10.1158/1078-0432.CCR-18-1967 10.1038/icb.1975.3 10.1146/annurev.immunol.14.1.233 10.1172/JCI12432 10.1038/nrc3239 10.1158/0008-5472.CAN-15-2347 10.3389/fimmu.2017.01707 10.1111/imm.13235 10.1038/s41591-018-0217-1 10.1016/j.jneuroim.2013.02.010 10.1038/sj.leu.2402903 10.1200/JCO.2016.69.3812 10.1136/jitc-2020-002097 10.1001/jamaoncol.2019.2244
Journal of Translational Medicine; Wu Y, Shrestha P et. al.

May 14th, 2022 - The two oncogenic human gammaherpesviruses, Kaposi sarcoma-associated herpesvirus (KSHV) and Epstein-Barr virus (EBV), both downregulate immune surface molecules, such as MHC-I, ICAM-1, and B7-2, enabling them to evade T-cell and natural killer ce...

Abemaciclib in Patients With HIV-associated and HIV-negative Kaposi Sarcoma
https://clinicaltrials.gov/ct2/show/NCT04941274

May 13th, 2022 - Background: Kaposi Sarcoma (KS) is a multicentric angioproliferative tumor, caused by Kaposi sarcoma-associated herpesvirus, that most frequently involves the skin, but may also involve lymph nodes, lungs, bone and gastrointestinal tract. It is mo...

Natural History of KSHV-Associated Multicentric Castleman s Disease
https://clinicaltrials.gov/ct2/show/NCT04968288

May 13th, 2022 - Background: Multicentric Castleman s disease (MCD) is a rare but lethal Kaposi s sarcoma-associated herpesvirus (KSHV) associated lymphoproliferative disorder with a historical median survival of 2 years. It occurs more often in HIV-infected indiv...

History of the KSHV Inflammatory Cytokine Syndrome (KICS)
https://clinicaltrials.gov/ct2/show/NCT01419561

May 13th, 2022 - BACKGROUND: KSHV inflammatory cytokine syndrome (KICS) is a newly recognized syndrome caused by Kaposi sarcoma-associated herpesvirus (KSHV). It is characterized by severe inflammatory symptoms including fevers, wasting, cytopenias, hypoalbuminemi...

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Drugs  2 results see all →

Clinicaltrials.gov  20 results

Abemaciclib in Patients With HIV-associated and HIV-negative Kaposi Sarcoma
https://clinicaltrials.gov/ct2/show/NCT04941274

May 13th, 2022 - Background: Kaposi Sarcoma (KS) is a multicentric angioproliferative tumor, caused by Kaposi sarcoma-associated herpesvirus, that most frequently involves the skin, but may also involve lymph nodes, lungs, bone and gastrointestinal tract. It is mo...

Natural History of KSHV-Associated Multicentric Castleman s Disease
https://clinicaltrials.gov/ct2/show/NCT04968288

May 13th, 2022 - Background: Multicentric Castleman s disease (MCD) is a rare but lethal Kaposi s sarcoma-associated herpesvirus (KSHV) associated lymphoproliferative disorder with a historical median survival of 2 years. It occurs more often in HIV-infected indiv...

History of the KSHV Inflammatory Cytokine Syndrome (KICS)
https://clinicaltrials.gov/ct2/show/NCT01419561

May 13th, 2022 - BACKGROUND: KSHV inflammatory cytokine syndrome (KICS) is a newly recognized syndrome caused by Kaposi sarcoma-associated herpesvirus (KSHV). It is characterized by severe inflammatory symptoms including fevers, wasting, cytopenias, hypoalbuminemi...

Molecular Characterization of Viral-associated Tumors, Tumors Occurring in the Setting of HIV or Other Immune Disorders and Castleman Disease
https://clinicaltrials.gov/ct2/show/NCT03300830

May 13th, 2022 - Background: The availability of high quality, clinically annotated patient samples is crucial for the study of biologic factors that influence the natural history of viral related malignancies, malignancies occurring in the setting of HIV, and Cas...

Testing the Combination of the Anti-cancer Drugs XL184 (Cabozantinib) and Nivolumab in Patients With Advanced Cancer and HIV
https://clinicaltrials.gov/ct2/show/NCT04514484

Apr 6th, 2022 - PRIMARY OBJECTIVES: I. To determine the safety of combined nivolumab and cabozantinib s-malate (XL184 [cabozantinib]) in human immunodeficiency virus (HIV) patients with advanced solid tumors. II. To determine the feasibility to deliver the combin...

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News  61 results

Leiomyosarcoma of the Penis: A Case Report and Re-Appraisal
https://www.mdedge.com/fedprac/article/254639/oncology/leiomyosarcoma-penis-case-report-and-re-appraisal
Zainub Ajmal, MBBS, Abdul Moiz Khan, MBBS et. al.

May 16th, 2022 - Penile cancer is rare with a worldwide incidence of 0. 8 cases per 100,000 men.

Risk of Dying From New Cancer Higher in Young Cancer Survivors
https://www.medscape.com/viewarticle/973908

May 12th, 2022 - Adolescent and young adult (AYA) cancer survivors face nearly a two-fold higher risk of dying from a new primary cancer compared with peers in the general population, new research shows. "These findings underscore the critical role of providing hi...

Pembrolizumab/Lenvatinib Combo Under Investigation in Classic Kaposi Sarcoma
https://www.onclive.com/view/pembrolizumab-lenvatinib-combo-under-investigation-in-classic-kaposi-sarcoma

Nov 9th, 2021 - For patients with classic Kaposi sarcoma who relapse following their first or second line of chemotherapy, treatment options are extremely limited, according to Alice Indini, MD. In an effort to expand options available to this population, the pha...

Dr. Indini on the Rationale for the PULSAR Trial in Classic Kaposi Sarcoma
https://www.onclive.com/view/dr-indini-on-the-rationale-for-the-pulsar-trial-in-classic-kaposi-sarcoma

Sep 27th, 2021 - Alice Indini, MD, medical oncologist, Medical Oncology Unit, Department of Internal Medicine, Fondazione IRCCS Ca’ Granda Ospedale Maggiore Policlinico, Milan, Italy, discusses the rationale for the phase 2 PULSAR trial in classic Kaposi sarcoma (...

The 5 Goals of Colonoscopy in Ulcerative Colitis
https://www.medscape.com/viewarticle/950489

May 21st, 2021 - This transcript has been edited for clarity. Hello. I'm Dr Stephen Hanauer from Northwestern University in Chicago, speaking to you today about the role of colonoscopy in the management of ulcerative colitis. There are several indications for perf...

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Patient Education  4 results see all →