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About 638 results

ALLMedicine™ Loeys-Dietz Syndrome Center

Research & Reviews  241 results

Complete Aortic Replacement in a Patient With Loeys-Dietz Syndrome.
https://doi.org/10.1177/15385744221109037
Vascular and Endovascular Surgery; Darigny S, Astarci P et. al.

Jun 16th, 2022 - Background: LDS is an autosomal dominant connective tissue disease. It is a rare multi-systemic disorder with serious vascular impact. Case report: We report a case of a 38-year-old male with Loeys-Dietz syndrome (LDS) suffering from major aortic ...

Different ascending aortic phenotypes with similar mutations in two patients with Loeys...
https://doi.org/10.1093/icvts/ivac159
Interactive Cardiovascular and Thoracic Surgery; Heck R, Fischer-Zirnsak B et. al.

Jun 12th, 2022 - We present two infant patients with confirmed Loeys-Dietz syndrome. The missense mutations in exon 7 of the TGFBR2 gene are lying only five codons apart (c.1597T>C and c.1582C>G). Phenotypically, the aneurysms of the ascending aorta were restricte...

Pain and fatigue in adults with Loeys-Dietz syndrome and vascular Ehlers-Danlos syndrom...
https://doi.org/10.1002/ajmg.a.62858
American Journal of Medical Genetics. Part A; Heidi J, Gry V et. al.

Jun 11th, 2022 - The purpose was to study self-reported chronic pain and fatigue symptoms among adults with molecularly verified Loeys-Dietz and vascular Ehlers-Danlos syndrome using a cross-sectional questionnaire design. Seventy adults were invited through a Nat...

Clinical features and complications of Loeys-Dietz syndrome: A systematic review.
https://doi.org/10.1016/j.ijcard.2022.05.065
International Journal of Cardiology; Gouda P, Kay R et. al.

Jun 7th, 2022 - Loeys-Dietz syndrome (LDS) is a connective tissue disorder that arises from mutations altering the transforming growth factor β signalling pathway. Due to the recent discovery of the underlying genetic mutations leading to LDS, the spectrum of cha...

Talipes Equinovarus in Loeys-Dietz Syndrome.
https://doi.org/10.1097/BPO.0000000000002180
Journal of Pediatric Orthopedics; Badin D, Atwater LC et. al.

May 26th, 2022 - Loeys-Dietz syndrome (LDS) commonly presents with foot deformities, such as talipes equinovarus (TEV), also known as "clubfoot." Although much is known about the treatment of idiopathic TEV, very little is known about the treatment of TEV in LDS. ...

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Guidelines  1 results

Consensus statement on surgical pathology of the aorta from the Society for Cardiovascu...
https://doi.org/10.1016/j.carpath.2016.03.002
Cardiovascular Pathology : the Official Journal of the So... Halushka MK, Angelini A et. al.

Apr 1st, 2016 - Surgical aortic specimens are usually examined in Pathology Departments as a result of treatment of aneurysms or dissections. A number of diseases, genetic syndromes (Marfan syndrome, Loeys-Dietz syndrome, etc.), and vasculopathic aging processes ...

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Clinicaltrials.gov  1 results

Thoracic Aortic Dilatation Syndromes
https://clinicaltrials.gov/ct2/show/NCT02111668

May 2nd, 2018 - Background Aortic dilatation syndromes are comprised by a group of different syndromes, of which Marfan syndrome is the best described. Marfan syndrome is a heritable connective tissue disorder associated with mutations in the fibrillin-1 gene (FB...

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News  11 results

Aortic repair in Loeys-Dietz syndrome requires close follow-up
https://www.mdedge.com/surgery/article/131742/interventional-cardiology-surgery/aortic-repair-loeys-dietz-syndrome-requires
Richard Mark Kirkner

Feb 21st, 2017 - The knowledge about Loeys-Dietz syndrome has evolved quickly since Hal Dietz, MD, and Bart Loeys, MD, at Johns Hopkins University, Baltimore, first reported on it in 2005. Now, another team of Johns Hopkins investigators have reported that an aggr.

Aortic repair in Loeys-Dietz syndrome requires close follow-up
https://www.mdedge.com/cardiology/article/131742/interventional-cardiology-surgery/aortic-repair-loeys-dietz-syndrome
Richard Mark Kirkner

Feb 21st, 2017 - The knowledge about Loeys-Dietz syndrome has evolved quickly since Hal Dietz, MD, and Bart Loeys, MD, at Johns Hopkins University, Baltimore, first reported on it in 2005. Now, another team of Johns Hopkins investigators have reported that an aggr.

AATS: Simplified mitral valve repair effective in children with Marfan’s
https://www.mdedge.com/surgery/article/99547/interventional-cardiology-surgery/aats-simplified-mitral-valve-repair
Richard Mark Kirkner

May 10th, 2015 - NEW YORK – A simplified surgical approach that uses an adult-sized, basic ring annuloplasty with a complete edge-to-edge leaflet repair has been found to yield good outcomes in a group of children with connective tissue disorders like Marfan syndr.

AATS: Simplified mitral valve repair effective in children with Marfan’s
https://www.mdedge.com/cardiology/article/99547/interventional-cardiology-surgery/aats-simplified-mitral-valve-repair
Richard Mark Kirkner

May 10th, 2015 - NEW YORK – A simplified surgical approach that uses an adult-sized, basic ring annuloplasty with a complete edge-to-edge leaflet repair has been found to yield good outcomes in a group of children with connective tissue disorders like Marfan syndr.

Multiple Milia Signal Need for Genetic Testing
https://www.mdedge.com/dermatology/article/55359/dermatology/multiple-milia-signal-need-genetic-testing
Damian McNamara

Jul 19th, 2012 - ORLANDO – Loeys-Dietz syndrome is a rare genetic disease that can be life threatening if not caught early, said Dr. Milan J.

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Patient Education  1 results see all →