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About 363 results

ALLMedicine™ Protein S Deficiency Center

Research & Reviews  133 results

An Atypical Case of Idiopathic Purpura Fulminans.
https://doi.org/10.1097/MPH.0000000000002497
Journal of Pediatric Hematology/oncology; Samman K, Le CK et. al.

Jun 15th, 2022 - Idiopathic purpura fulminans (PF) is rare but has been reported in pediatric patients, commonly following infections. We present a case of a 5-year-old boy, heterozygous for factor V Leiden, with no history of recent infections, who presented with...

Cerebral venous sinus thrombosis and dural arteriovenous fistula associated with protei...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9059366
BMC Neurology; Liang H, Xu C et. al.

May 4th, 2022 - To describe the characteristics of patients with cerebral venous sinus thrombosis (CVST) and dural arteriovenous fistula (AVF) associated with protein S (PS) deficiency. We conducted a search of medical records in Hainan General Hospital from Janu...

APA scoring system: a novel predictive model based on risk factors of pregnancy loss fo...
https://doi.org/10.1080/01443615.2021.2021507
Journal of Obstetrics and Gynaecology : the Journal of Th... Dai YF, Lin LZ et. al.

Jan 21st, 2022 - The aim of this study was to analyse the risk factors of pregnancy loss of patients with recurrent spontaneous abortion (RSA) and develop a scoring system to predict RSA. Clinical data of 242 cases, with RSA who were treated at Fujian Provincial M...

Rapid identification of a pathogenic variant of PROS1 in a thrombophilic family by whol...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8718207
Medicine Zhang W, Huang C et. al.

Dec 31st, 2021 - Venous thrombosis remains a significant problem in modern days. Genetic factors contribute to a subset of patients with venous thrombosis. It is sometimes challenging to identify the underlying culprit in thrombophilic individuals based on traditi...

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Guidelines  1 results

EFNS guideline on the treatment of cerebral venous and sinus thrombosis in adult patients.
https://doi.org/10.1111/j.1468-1331.2010.03011.x
European Journal of Neurology; Einhäupl K, Stam J et. al.

Apr 21st, 2010 - Cerebral venous and sinus thrombosis (CVST) is a rather rare disease which accounts for <1% of all strokes. Diagnosis is still frequently overlooked or delayed as a result of the wide spectrum of clinical symptoms and the often subacute or lingeri...

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Clinicaltrials.gov  4 results

Thromboprophylaxis in Pregnant Women in Hospital: A Prospective Clinical Trial
https://clinicaltrials.gov/ct2/show/NCT02600260

Apr 28th, 2021 - Thromboembolic events are among the leading causes of maternal morbidity and mortality in pregnancy / postpartum period. They are the leading cause of maternal death in developed countries. Risk factors for venous thromboembolism (VTE) during preg...

Validation of a Novel Dabigatran Based Peri-Operative Bridging Anticoagulation Protocol for Patients on Chronic Warfarin Therapy
https://clinicaltrials.gov/ct2/show/NCT01810237

Jan 31st, 2017 - Subject Selection: The study population will include low risk patients on long-term warfarin therapy for venous thromboembolic disease (VTE) followed by the hematology anticoagulation clinic. Low risk will be defined as status greater than 12 mont...

Prevention of Unexplained Recurrent Abortion by Enoxaparine
https://clinicaltrials.gov/ct2/show/NCT00740545

Mar 5th, 2015 - Standard investigations fail to reveal any apparent cause in 50% of the cases of recurrent spontaneous abortion. Prothrombotic mechanisms were initially evoked. Factor V Leiden, Prothrombin G20210A mutation and protein S deficiency are implicated ...

Prevalence of Clinical and Laboratory Markers of Hypofibrinolysis in Psychotic Patients
https://clinicaltrials.gov/ct2/show/NCT01487291

Dec 16th, 2014 - If the thrombotic tendency plays a significant role in the etiology of psychosis, one would expect to find ischemic brain injuries in neuroimaging studies, but it does not happen. Therefore, if there is a correlation between thrombotic tendency-hy...

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News  7 results

Fast Five Quiz: Test Your Knowledge of Venous Thromboembolism
https://reference.medscape.com/viewarticle/902400_2

Dec 3rd, 2018 - Nephrotic syndrome is one of several disease states that increase a patient's risk of developing VTE. VTE associated with nephrotic syndrome appears to be due to a hypercoagulable state resulting from urinary loss of anticoagulant proteins, togeth...

Treatment of Melasma Using Tranexamic Acid: What’s Known and What’s Next
https://www.mdedge.com/dermatology/article/159214/pigmentation-disorders/treatment-melasma-using-tranexamic-acid-whats
Sarah L. Sheu, MD

Feb 22nd, 2018 - Tranexamic acid is a synthetic lysine derivative that inhibits plasminogen activation by blocking lysine-binding sites on the plasminogen molecule. Although the US Food and Drug Administration–approved indications for tranexamic acid include treat.

VTE Prophylaxis Warranted in Pregnant Women With Rare Thrombophilias
https://www.medscape.com/viewarticle/888208

Nov 9th, 2017 - NEW YORK (Reuters Health) - Women with some rare forms of thrombophilia can benefit from ante- or postpartum thrombosis prophylaxis, but those with more common types generally do not need preventive treatment, according to a new meta-analysis. Pre...

Fistula developed after delivery: $50M verdict
https://www.mdedge.com/obgyn/article/137277/obstetrics/fistula-developed-after-delivery-50m-verdict

May 3rd, 2016 - Fistula developed after delivery: $50M verdict During delivery of a 31-year-old woman's baby, a nuchal cord was encountered. In order to safely deliver the child, the ObGyn performed an episiotomy.

VTE risk tied to natural anticoagulant deficiency
https://www.mdedge.com/anticoagulationhub/article/98890/thrombosis/vte-risk-tied-natural-anticoagulant-deficiency

Apr 19th, 2015 - Deficiency of the endogenous anticoagulant proteins antithrombin, protein C, and protein S are significantly associated with an increased risk of a first episode of venous thromboembolism, according to a study published in Thrombosis Research. To.

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