About 2,980 results

ALLMedicine™ Autoimmune Hepatitis Center

Research & Reviews  1,081 results

Behaviors, symptoms, and outcomes of North American patients with autoimmune hepatitis ...
Journal of Investigative Medicine : the Official Publicat... Vuppalanchi V, Gelow K et. al.

Jul 29th, 2021 - The management of patients with autoimmune hepatitis (AIH) in the era of SARS-CoV-2 is challenging given minimal published clinical data. We used a large cohort of patients with AIH across the USA to investigate the differences in known risk facto...

Postinfantile giant cell hepatitis in the setting of autoimmune hepatitis: exclusively ...
BMJ Case Reports; Teles C, Santos R et. al.

Jul 23rd, 2021 - Autoimmune hepatitis (AIH) is a rare chronic liver disease with a non-specific clinical presentation. Its physiopathology is not fully understood and, if untreated, can progress to cirrhosis and even fulminant liver failure. Here, we describe a ca...

Acute autoimmune-like hepatitis with atypical anti-mitochondrial antibody after mRNA CO...
Journal of Autoimmunity; Ghielmetti M, Schaufelberger HD et. al.

Jul 23rd, 2021 - Autoimmune phenomena and clinically apparent autoimmune diseases, including autoimmune hepatitis, are increasingly been reported not only after natural infection with the SARS-CoV-2 virus, but also after vaccination against it. We report the case ...

Recent advances in clinical practice: epidemiology of autoimmune liver diseases.
Gut Trivedi PJ, Hirschfield GM

Jul 17th, 2021 - Autoimmune liver diseases are chronic inflammatory hepatobiliary disorders that when classically defined encompass three distinctive clinical presentations; primary biliary cholangitis (PBC), primary sclerosing cholangitis (PSC) and autoimmune hep...

Managing abnormal liver tests in children with inflammatory bowel disease.
Current Opinion in Pediatrics; van Rheenen PF

Jul 16th, 2021 - Liver test abnormalities in children with inflammatory bowel disease (IBD) are usually insidious in onset. By the time that symptoms referable to liver disease have appeared, the liver injury may be well advanced. It is, therefore, important that ...

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Guidelines  3 results

Diagnosis and Management of Autoimmune Hepatitis in Adults and Children: 2019 Practice ...
Hepatology (Baltimore, Md.); Mack CL, Adams D et. al.

Dec 22nd, 2019 - Diagnosis and Management of Autoimmune Hepatitis in Adults and Children: 2019 Practice Guidance and Guidelines From the American Association for the Study of Liver Diseases.|2019|Mack CL,Adams D,Assis DN,Kerkar N,Manns MP,|diagnosis,drug therapy,

ACG Clinical Guideline: Evaluation of Abnormal Liver Chemistries.
The American Journal of Gastroenterology; Kwo PY, Cohen SM et. al.

Dec 21st, 2016 - Clinicians are required to assess abnormal liver chemistries on a daily basis. The most common liver chemistries ordered are serum alanine aminotransferase (ALT), aspartate aminotransferase (AST), alkaline phosphatase and bilirubin. These tests sh...

Diagnosis and management of autoimmune hepatitis.
Hepatology (Baltimore, Md.); Manns MP, Czaja AJ et. al.

Jun 1st, 2010 - Diagnosis and management of autoimmune hepatitis.|2010|Manns MP,Czaja AJ,Gorham JD,Krawitt EL,Mieli-Vergani G,|blood,diagnosis,drug therapy,immunology,pathology,

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Drugs  8 results see all →

Clinicaltrials.gov  20 results

Budesonide for Liver Transplant Immune Suppression

Mar 24th, 2020 - Enrollment of Subjects: All consecutive patients undergoing liver transplant (LT) at the University Of Cincinnati Transplant Center will be screened for enrollment upon admission for transplant surgery. Subjects will be approached after permission...

ADCC Mediated B-Cell dEpletion and BAFF-R Blockade

Mar 12th, 2020 - This is a randomized, placebo-controlled, double-blind dose range study in autoimmune hepatitis. The study population consists of female and male adult autoimmune hepatitis patients with incomplete response or intolerant to standard treatment of c...

Biomarkers to Predict the Success of Immunosuppression Withdrawal in Autoimmune Hepatitis

Feb 12th, 2020 - Study design: This is a prospective not controlled, not randomized, unicentric study to establish predictive biomarkers for a safe and effective treatment withdrawal in patients with type 1 AIH. Length of the study: Screening is expected to take a...

Assessing Kids for Liver Inflammation and Fibrosis Using Non-invasive MRI

Sep 17th, 2018 - The most serious pandemic facing Europe is fatty liver disease and non-alcoholic steatohepatitis (NASH). The main causal factor is obesity: according to recent statistics 11.8m-16.3m European children are overweight, of which 2.9m - 4.4m are obese...

Induction of Regulatory t Cells by Low Dose il2 in Autoimmune and Inflammatory Diseases

Aug 20th, 2018 - Protocol: TRANSREG is a multicentric, uncontrolled, open-label study, comparing biological and clinical responses to the administration of low doses IL2 across 14 selected pathologies: rheumatoid arthritis, ankylosing spondylitis, systemic lupus e...

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News  75 results

Worse Survival With Recurrent Autoimmune Hepatitis After Transplant

Jul 1st, 2021 - Autoimmune hepatitis that recurs following a liver transplant can impair both graft survival and overall survival, results of a large international study showed. Among 736 patients with autoimmune hepatitis who underwent liver transplant and were ...

Incidence of Autoimmune Hepatitis May Be Rising

Feb 2nd, 2021 - The incidence of autoimmune hepatitis (AIH) may be rising, according to a prospective population-based study conducted in New Zealand. From 2008 to 2016, the rising incidence of AIH led to a 40% increase in point prevalence, reported lead author M...

Treating Liver Disease During COVID-19: New Recommendations

May 14th, 2020 - Find the latest COVID-19 news and guidance in Medscape's Coronavirus Resource Center. The COVID-19 pandemic presents myriad challenges to hepatologists, gastroenterologists, transplant programs, primary care providers, and, of course, their patien...

AASLD: Liver transplants should proceed despite COVID-19
M. Alexander Otto, MDedge News

Apr 1st, 2020 - In liver transplant recipients or patients with autoimmune hepatitis on immunosuppressive therapy, acute cellular rejection or disease flare should not be presumed in the face of active coronavirus disease 2019 (COVID-19), according to the America.

CymaBay Therapeutics scraps two studies of liver drug; shares plunge

Nov 25th, 2019 - (Reuters) - CymaBay Therapeutics Inc said on Monday it was scrapping two mid-stage trials of its liver disease drug, after biopsies found a type of liver damage in some patients, sending its shares down over 75%. The drug developer said it had obs...

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Patient Education  5 results see all →