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About 22 results

ALLMedicine™ Aromatase Excess Syndrome Center

Research & Reviews  11 results

Long-term effect of aromatase inhibition in aromatase excess syndrome.
https://doi.org/10.1210/clinem/dgab054
The Journal of Clinical Endocrinology and Metabolism; Binder G, Nakamura A et. al.

Jan 29th, 2021 - Aromatase excess syndrome (AEXS) is a very rare disorder characterized by prepubertal gynecomastia, bone age acceleration and early growth arrest. Heterozygote submicroscopic rearrangements within the promotor of CYP19A1 result in overexpression o...

Aromatase excess syndrome in a Chinese boy due to a novel duplication at 15q21.2.
https://doi.org/10.1515/jpem-2018-0266
Journal of Pediatric Endocrinology & Metabolism : JPEM; Tan X, Wu X et. al.

Dec 11th, 2018 - Background Aromatase excess syndrome (AEXS) is a rare autosomal dominant disorder caused by CYP19A1 overexpression. Clinical manifestations of AEXS include pre- or peri-pubertal gynecomastia, advanced bone age and compromised adult height. Case pr...

Aromatase excess syndrome
https://rarediseases.info.nih.gov/diseases/12494/aromatase-excess-syndrome

Aug 31st, 2017 - The following summary is from Orphanet, a European reference portal for information on rare diseases and orphan drugs. Orpha Number: 178345 Definition A rare, genetic endocrine disease characterized by increased levels of estrogen due to elevated ...

Aromatase excess syndrome: a rare autosomal dominant disorder leading to pre- or peri-p...
https://www.ncbi.nlm.nih.gov/pubmed/24716396
Pediatric Endocrinology Reviews : PER; Fukami M, Miyado M et. al.

Apr 10th, 2014 - Overexpression of CYP19A1 encoding aromatase results in a rare genetic disorder referred to as aromatase excess syndrome (AEXS). Male patients with AEXS manifest pre- or peri-pubertal onset gynecomastia, gonadotropin deficiency, and advanced bone ...

Genomic basis of aromatase excess syndrome: recombination- and replication-mediated rea...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5399493
The Journal of Clinical Endocrinology and Metabolism; Fukami M, Tsuchiya T et. al.

Sep 25th, 2013 - Genomic rearrangements at 15q21 have been shown to cause overexpression of CYP19A1 and resultant aromatase excess syndrome (AEXS). However, mutation spectrum, clinical consequences, and underlying mechanisms of these rearrangements remain to be el...

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Clinicaltrials.gov  11 results

Long-term effect of aromatase inhibition in aromatase excess syndrome.
https://doi.org/10.1210/clinem/dgab054
The Journal of Clinical Endocrinology and Metabolism; Binder G, Nakamura A et. al.

Jan 29th, 2021 - Aromatase excess syndrome (AEXS) is a very rare disorder characterized by prepubertal gynecomastia, bone age acceleration and early growth arrest. Heterozygote submicroscopic rearrangements within the promotor of CYP19A1 result in overexpression o...

Aromatase excess syndrome in a Chinese boy due to a novel duplication at 15q21.2.
https://doi.org/10.1515/jpem-2018-0266
Journal of Pediatric Endocrinology & Metabolism : JPEM; Tan X, Wu X et. al.

Dec 11th, 2018 - Background Aromatase excess syndrome (AEXS) is a rare autosomal dominant disorder caused by CYP19A1 overexpression. Clinical manifestations of AEXS include pre- or peri-pubertal gynecomastia, advanced bone age and compromised adult height. Case pr...

Aromatase excess syndrome
https://rarediseases.info.nih.gov/diseases/12494/aromatase-excess-syndrome

Aug 31st, 2017 - The following summary is from Orphanet, a European reference portal for information on rare diseases and orphan drugs. Orpha Number: 178345 Definition A rare, genetic endocrine disease characterized by increased levels of estrogen due to elevated ...

Aromatase excess syndrome: a rare autosomal dominant disorder leading to pre- or peri-p...
https://www.ncbi.nlm.nih.gov/pubmed/24716396
Pediatric Endocrinology Reviews : PER; Fukami M, Miyado M et. al.

Apr 10th, 2014 - Overexpression of CYP19A1 encoding aromatase results in a rare genetic disorder referred to as aromatase excess syndrome (AEXS). Male patients with AEXS manifest pre- or peri-pubertal onset gynecomastia, gonadotropin deficiency, and advanced bone ...

Genomic basis of aromatase excess syndrome: recombination- and replication-mediated rea...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5399493
The Journal of Clinical Endocrinology and Metabolism; Fukami M, Tsuchiya T et. al.

Sep 25th, 2013 - Genomic rearrangements at 15q21 have been shown to cause overexpression of CYP19A1 and resultant aromatase excess syndrome (AEXS). However, mutation spectrum, clinical consequences, and underlying mechanisms of these rearrangements remain to be el...

see more →