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About 4,543 results

ALLMedicine™ Acromegaly Center

Research & Reviews  1,473 results

Dissecting the in vitro efficacy of octreotide and cabergoline in GH- and GH/PRL-secret...
https://doi.org/10.1210/clinem/dgac675
The Journal of Clinical Endocrinology and Metabolism; Gatto F, Feelders RA et. al.

Nov 23rd, 2022 - Cabergoline (CAB) is an off-label medical therapy for acromegaly, overshadowed by first-generation somatostatin receptor ligands, e.g. octreotide (OCT). Head-to-head comparison between OCT and CAB in inhibiting growth hormone (GH) secretion in pri...

Prominent skin folds of the scalp provide a superficial clue in acromegaly.
https://doi.org/10.1016/S0140-6736(22)01638-5
Lancet (London, England); Sánchez-Meza E, Kubelis-López DE et. al.

Nov 21st, 2022 - Prominent skin folds of the scalp provide a superficial clue in acromegaly.|2022|Sánchez-Meza E,Kubelis-López DE,Ocampo-Candiani J,Chavez-Alvarez S,|diagnosis,

Can telemedicine improve adherence to medical treatment? Lessons learned from research ...
https://doi.org/10.20945/2359-3997000000576
Archives of Endocrinology and Metabolism; Boguszewski CL

Nov 18th, 2022 - Can telemedicine improve adherence to medical treatment? Lessons learned from research on acromegaly conducted during COVID-19 pandemic.|2022|Boguszewski CL,|drug therapy,

The state of Sergipe contribution to GH research: from Souza Leite to Itabaianinha synd...
https://doi.org/10.20945/2359-3997000000567
Archives of Endocrinology and Metabolism; Aguiar-Oliveira MH, Salvatori R

Nov 18th, 2022 - In the late 19th century, José Dantas de Souza Leite, a physician born in Sergipe, published the first detailed clinical description of acromegaly under the guidance of the French neurologist Pierre Marie. In 2014, the Brazilian Society of Endocri...

Evaluating home injection compared with healthcare-setting injection of somatostatin an...
https://doi.org/10.1007/s12020-022-03227-0
Endocrine Boguszewski CL, Korbonits M et. al.

Nov 13th, 2022 - A systematic literature review was conducted to assess the use of home injections (self/partner/healthcare provider [HCP]-administered) of somatostatin analogs (SSAs) as an alternative to healthcare-setting injections in patients with acromegaly a...

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Guidelines  5 results

Italian Society for the Study of Diabetes (SID)/Italian Endocrinological Society (SIE) ...
https://doi.org/10.1016/j.numecd.2016.02.001
Nutrition, Metabolism, and Cardiovascular Diseases : NMCD; Baroni MG, Giorgino F et. al.

Feb 26th, 2016 - Hyperglycemia is a common feature associated with states of increased growth hormone secretion and glucocorticoid levels. The purpose of these guidelines is to assist clinicians and other health care providers to take evidence-based therapeutic de...

Expert consensus document: A consensus on the medical treatment of acromegaly.
https://doi.org/10.1038/nrendo.2014.21
Nature Reviews. Endocrinology; Giustina A, Chanson P et. al.

Feb 26th, 2014 - In March 2013, the Acromegaly Consensus Group met to revise and update guidelines for the medical treatment of acromegaly. The meeting comprised experts skilled in the medical management of acromegaly. The group considered treatment goals covering...

American Association of Clinical Endocrinologists medical guidelines for clinical pract...
https://www.ncbi.nlm.nih.gov/pubmed/21846616
Endocrine Practice : Official Journal of the American Col... Katznelson L, Atkinson JL et. al.

Aug 24th, 2011 - American Association of Clinical Endocrinologists medical guidelines for clinical practice for the diagnosis and treatment of acromegaly--2011 update.|2011|Katznelson L,Atkinson JL,Cook DM,Ezzat SZ,Hamrahian AH,|diagnosis,therapy,standards,trends,...

AME Position Statement on clinical management of acromegaly.
https://www.ncbi.nlm.nih.gov/pubmed/19923883
Journal of Endocrinological Investigation; Cozzi R, Baldelli R et. al.

Jan 23rd, 2010 - AME Position Statement on clinical management of acromegaly.|2010|Cozzi R,Baldelli R,Colao A,Lasio G,Zini M,|diagnosis,economics,epidemiology,therapy,

Guidelines for acromegaly management: an update.
https://doi.org/10.1210/jc.2008-2421
The Journal of Clinical Endocrinology and Metabolism; Melmed S, Colao A et. al.

Feb 12th, 2009 - The Acromegaly Consensus Group reconvened in November 2007 to update guidelines for acromegaly management. The meeting participants comprised 68 pituitary specialists, including neurosurgeons and endocrinologists with extensive experience treating...

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Drugs  30 results see all →

Clinicaltrials.gov  176 results

Lanreotide as Primary Treatment for Acromegalic Patients With Pituitary Gland Macroadenoma
https://clinicaltrials.gov/ct2/show/NCT00690898

Oct 14th, 2022 - Acromegaly is a chronic disease caused by excessive secretion of growth hormone (GH) and mainly due to benign tumour localized in the pituitary gland. The disease develops insidiously, causing a gradual progression of symptoms; consequently most p...

Genetic Studies of Insulin and Diabetes
https://clinicaltrials.gov/ct2/show/NCT00001987

Oct 14th, 2022 - Study Description: Insulin is the key hormone responsible for regulating the level of glucose in plasma. In several disease states (e.g., obesity, type 2 diabetes, and acromegaly), the target cells are resistant to insulin action. Insulin resistan...

Real-World Study (RWS) of Lanreotide Autogel (LAN) for the Treatment of Patients With Acromegaly in China
https://clinicaltrials.gov/ct2/show/NCT05431803

Oct 14th, 2022 - This study aims to assess the one-year effectiveness and safety of LAN among patients with acromegaly in China in routine clinical practice. In addition, the study is designed to understand the real-world treatment patterns and outcomes of LAN amo...

A Study to Evaluate the Long-Term Safety and Efficacy of Paltusotine for the Treatment of Acromegaly (ACROBAT Advance)
https://clinicaltrials.gov/ct2/show/NCT04261712

Oct 6th, 2022 - A phase 2, open label, long-term extension study designed to evaluate the safety and efficacy of paltusotine (formerly CRN00808; an oral selective nonpeptide somatostatin receptor type 2 biased agonist) in subjects with acromegaly.

A Study to Evaluate the Safety and Efficacy of Paltusotine for the Treatment of Acromegaly (PATHFNDR-2)
https://clinicaltrials.gov/ct2/show/NCT05192382

Oct 6th, 2022 - A randomized, placebo-controlled study designed to evaluate the safety and efficacy of paltusotine (formerly CRN00808; an oral selective nonpeptide somatostatin receptor type 2 biased agonist) in subjects with non-pharmacologically treated acromeg...

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News  121 results

Super-Ager Brains; NIA Issues Lecanemab Statement; New NFL Concussion Protocol?
https://www.medpagetoday.com/neurology/generalneurology/101053

Oct 4th, 2022 - In super-agers -- people 80 and older with exceptional episodic memory -- entorhinal cortex neurons were significantly larger compared with cognitively average peers and individuals 20-30 years younger. (Journal of Neuroscience) A multimodal pain ...

When to Treat Low Testosterone in Diabetes and Obesity
https://www.medscape.com/viewarticle/977284

Jul 15th, 2022 - Men with type 2 diabetes are at higher risk for testosterone deficiency. And in turn, hypogonadism is commonly associated with metabolic syndrome or type 2 diabetes. However, this does not imply a specific need for action, as Stephan Petersenn, MD...

FDA Halts Diabetes Cell Tx Trial; Europe's Obesity Epidemic; Acromegaly Fractures
https://www.medpagetoday.com/endocrinology/generalendocrinology/98544

May 4th, 2022 - The FDA placed a clinical hold on Vertex's investigational diabetes cell therapy VX-880, saying the company didn't have enough evidence to support a treatment dose increase. (Fierce Biotech) A study from England found that surgeons who performed f...

Practice Guidelines Highlights From the Past Year
https://www.medscape.com/viewarticle/969871

Mar 8th, 2022 - Dr Douglas S. Paauw A 64-year-old woman is evaluated for fever, diarrhea, and abdominal pain. She was diagnosed with Clostridioides difficile 2 months ago and completed a 10-day course of vancomycin. Her stool toxin test is positive for Clostridio...

Practice guidelines highlights from past year
https://www.mdedge.com/internalmedicine/article/252401/infectious-diseases/practice-guidelines-highlights-past-year
Douglas S. Paauw, MD

Mar 3rd, 2022 - A 64-year-old woman is evaluated for fever, diarrhea, and abdominal pain. She was diagnosed with Clostridioides difficile 2 months ago and completed a 10-day course of vancomycin.

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Patient Education  12 results see all →