ALLMedicine™ Aniridia Center

Jan 18th, 2022 - Aniridia is a congenital, panocular disease that can affect the cornea, anterior chamber angle, iris, lens, retina and optic nerve. PAX6 loss-of-function variants are the most common cause of aniridia, and variants throughout the gene have been li...

Jan 13th, 2022 - Polycystic Ovarian Syndrome (PCOS), the most common reproductive endocrine disorder affecting premenopausal women, is frequently associated with central obesity and pancreatic β-cell dysfunction. Aniridia, a rare congenital eye disorder with haplo...

Jan 13th, 2022 - To determine in vitro, using a translational research approach before realizing the procedure in a patient with iatrogenic aphakia and partial aniridia, whether suturing a trifocal intraocular lens (IOL) to an artificial iris degrades the IOL's op...

Jan 11th, 2022 - To determine the long-term outcomes of a cohort of complex patients with primary congenital glaucoma, aniridia and anterior segment dysgenesis. Retrospective consecutive series between 1990-2021 in two UK tertiary centres: Guy's and St Thomas' NHS...

Dec 24th, 2021 - To correlate the degree of foveal hypoplasia in congenital aniridia with visual acuity, iris phenotype, and PAX6 mutations. Retrospective case series. 95 consecutive patients with high quality Spectral-domain optical coherence tomography (SD-OCT) ...

Dec 15th, 2021 - Aniridia is a condition in which the iris, the colored portion of the eye, is either partially or completely absent. The iris is responsible for regulating the amount of light entering the eye by adjusting the size of the pupil. Aniridia can eithe...

Mar 29th, 2021 - Albinism is a genetic condition, resulting from mutations in at least 19 known genes responsible for the production of melanin in the skin, hair and eyes. Ophthalmological manifestations are a constant feature of this disease. Albinism is believed...

Jul 24th, 2018 - This is a prospective, non-randomized, unmasked pilot study. SETTING: Storm Eye Institute, Medical University of South Carolina, Charleston, SC and one additional site in USA. SUBJECTS A total of 40 eyes (20 per site) of 20 subjects of both sexes ...

Jul 2nd, 2017 - This project, Phenotype-Genotype Correlation in aniridia, will study the specific mutations in patients with aniridia and attempt to make a phenotype-genotype correlation. Specifically, the study will determine whether specific mutations are more ...

Mar 22nd, 2019 - Discussion Anterior polar cataracts constitute approximately 3% of congenital cataracts.[1] They appear as small opacities on the anterior surface of lens. There are three subtypes of anterior polar cataracts: polar, subcapsular, and pyramidal. Po...

May 30th, 2018 - The FDA approved the first stand-alone prosthetic iris on Wednesday for adults and children with aniridia, a rare congenital condition, or other damage to the eye. Made of thin and foldable medical-grade silicone, CustomFlex Artificial Iris is ind...

Apr 12th, 2010 - April 12, 2010 — Acquired childhood glaucoma is more prevalent than congenital types of glaucoma, according to the results of a population-based study reported in the April issue of the Archives of Ophthalmology. "Childhood glaucoma is an uncommon...