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About 1,253 results

ALLMedicine™ Chronic Granulomatous Disease Center

Research & Reviews  479 results

Elemental Diet for Treatment of Inflammatory Bowel Disease in Patients With Chronic Granulomatous Disease
https://clinicaltrials.gov/ct2/show/NCT03983837

May 20th, 2022 - Chronic granulomatous disease (CGD) is a rare genetic immune disorder that results in recurrent and severe infections, and inflammatory dysregulation. For almost 50% of patients with CGD, this inflammation causes severe inflammatory bowel disease ...

Fatal invasive aspergillosis in a child with chronic granulomatous disease.
https://doi.org/10.12968/jowc.2022.31.5.427
Journal of Wound Care; Sarvestani HK, Ansari S et. al.

May 18th, 2022 - Patients with chronic granulomatous disease, a primary immunodeficiency, experience granulomatous complications and recurrent life-threatening opportunistic bacterial and fungal infections. In this article, we report on a case of invasive aspergil...

Outbreak of healthcare-associated bacteremia caused by Burkholderia gladioli due to con...
https://doi.org/10.1016/j.ijid.2022.05.012
International Journal of Infectious Diseases : IJID : Off... Dobrović K, Mareković I et. al.

May 14th, 2022 - Burkholderia gladioli has been associated with infections in patients with cystic fibrosis, chronic granulomatous disease and other immunocompromising conditions. The aim of this study was to better depict the outbreak of healthcare-associated bac...

IFNγ Regulates NAD+ Metabolism to Promote the Respiratory Burst in Human Monocytes.
https://doi.org/10.1182/bloodadvances.2021005776
Blood Advances; McCann KJ, Christensen SM et. al.

May 3rd, 2022 - IFNγ is an essential and pleiotropic activator of human monocytes, but little is known about the changes in cellular metabolism required for IFNγ-induced activation. We sought to elucidate the mechanisms by which IFNγ reprograms monocyte metabolis...

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Drugs  2 results see all →

Clinicaltrials.gov  13 results

Elemental Diet for Treatment of Inflammatory Bowel Disease in Patients With Chronic Granulomatous Disease
https://clinicaltrials.gov/ct2/show/NCT03983837

May 20th, 2022 - Chronic granulomatous disease (CGD) is a rare genetic immune disorder that results in recurrent and severe infections, and inflammatory dysregulation. For almost 50% of patients with CGD, this inflammation causes severe inflammatory bowel disease ...

Non-Invasive Assessment of Atherosclerosis in Patients With CGD and Other Disorders of the Immune System
https://clinicaltrials.gov/ct2/show/NCT01063309

Jul 28th, 2021 - Heart disease kills more than half a million people in the U.S. each year. Atherosclerosis, the major cause of heart disease, is thought to relate to dysregulated inflammation in the cardiovascular system and possibly results from over production ...

Pharmacokinetics of Posaconazole in Children With Chronic Granulomatous Disease (CGD)
https://clinicaltrials.gov/ct2/show/NCT00799071

Nov 30th, 2020 - At this moment itraconazole is the drug of first choice in the prophylaxis of fungal infections in children with CGD. Breakthrough fungal infections while on itra-conazole prophylaxis are described in literature indicating the need for a drug with...

Radiofrequency Ablation for Liver Abscesses From Chronic Granulomatous Disease
https://clinicaltrials.gov/ct2/show/NCT01851460

Mar 26th, 2020 - Radiofrequency Ablation (RFA) has become an increasingly common therapeutic treatment for neoplasms in the liver. A number of devices are now Food and Drug Administration cleared for this indication, and a growing body of literature supports this ...

Pioglitazone Therapy for Chronic Granulomatous Disease
https://clinicaltrials.gov/ct2/show/NCT03080480

Oct 22nd, 2019 - Chronic granulomatous disease (CGD) is a rare genetic disease caused by defects in genes encoding the subunits of the nicotinamide adenine dinucleotide(NADPH)phosphate oxidase complex. In normal phagocytes peroxisome proliferator-activated recep...

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News  5 results

Anti-Migraine Drug Recalled Due to Potential Contamination
https://www.medscape.com/viewarticle/917018

Aug 19th, 2019 - Pfizer is recalling two lots of eletriptan hydrobromide (Relpax) 40-mg tablets because of potential contamination with Pseudomonas and Burkholderia bacteria, the company has announced. The drug is indicated for the acute treatment of migraine with...

Rare Disease Treatments Make Up Top 10 Most Costly Drugs
https://www.staging.medscape.com/viewarticle/879422

May 2nd, 2017 - UPDATED May 4, 2017 // The world's top 10 most expensive drugs are all orphan drugs for rare and ultrarare diseases, according to a new analysis. Leading that pack at number 1 is glycerol phenylbutyrate (Ravicti, Horizon Pharma), an orphan drug ap...

Rare Disease Treatments Make Up Top 10 Most Costly Drugs
https://www.medscape.com/viewarticle/879422

May 2nd, 2017 - UPDATED May 4, 2017 // The world's top 10 most expensive drugs are all orphan drugs for rare and ultrarare diseases, according to a new analysis. Leading that pack at number 1 is glycerol phenylbutyrate (Ravicti, Horizon Pharma), an orphan drug ap...

Dr. David C. Hohn Receives Courage Award
https://www.medscape.com/viewarticle/734751

Dec 22nd, 2010 - December 22, 2010 — Oncologist David C. Hohn, MD, from the Roswell Park Cancer Institute, Buffalo, New York, has been honored with the Gilda Radner Courage Award in recognition of his career achievements in cancer research, his administrative lead...

Carried by Immigrants, Leprosy in Heartland Surprises Clinicians
https://www.medpagetoday.com/infectiousdisease/publichealth/12284

Dec 29th, 2008 - Action Points Explain to interested patients that Hansen's disease -- more commonly known as leprosy -- is not easily transmissible and is readily cured with antibiotics if it is diagnosed early. Note that the incidence of leprosy in the U.S. is s...

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Patient Education  2 results see all →