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About 6,740 results

ALLMedicine™ Neurofibromatosis Center

Research & Reviews  2,539 results

Natural History and Biospecimen Acquisition for Children and Adults With Rare Solid Tumors
https://clinicaltrials.gov/ct2/show/NCT03739827

May 20th, 2022 - Background: Rare tumors are defined as fewer than 150 incident cases per one million per year. Consequently, only 11 tumor types are common in U.S. adults (prostate, breast, lung/bronchus, colon, uterus, bladder, melanoma, rectum, ovary, non-Hodgk...

Medication Adherence in Children, Adolescents and Adults With Neurofibromatosis Type 1 (NF1) on Clinical Treatment Trials
https://clinicaltrials.gov/ct2/show/NCT03531814

May 20th, 2022 - Background: Neurofibromatosis type 1 (NF1) is a genetic disorder that affects approximately 1 in 3,500 individuals and is associated with a broad variety of symptoms and physical findings. Plexiform neurofibromas (PN) are histologically benign tum...

Natural History Study of Children and Adults With Neuroendocrine Neoplasms (NEN)s
https://clinicaltrials.gov/ct2/show/NCT04488263

May 20th, 2022 - Background: Neuroendocrine neoplasm (NENs) are divided into neuroendocrine tumors (NETs) and neuroendocrine carcinomas (NECs). These are rare malignancies occurring for example in the gastrointestinal tract, islets of the pancreas, lung, adrenal m...

Relationship Stressors in Parents of Children With Cancer or Neurofibromatosis Type 1 (NF1)
https://clinicaltrials.gov/ct2/show/NCT01702922

May 20th, 2022 - Background: Parents face numerous stressors when their child is diagnosed with cancer or NF1, each of which can strain a marriage/partnership. Marital/partner relationship dynamics are often not assessed or addressed when providing health care for...

Pediatric vestibular schwannoma without evidence of neurofibromatosis: consecutive 18 m...
https://doi.org/10.1007/s00381-022-05477-9 10.1227/00006123-199107000-00003 10.1007/s003810050479 10.3171/jns.1952.9.4.0395 10.1097/00129492-200111000-00032 10.3892/ol.2015.3058 10.1007/s00701-019-04034-9 10.1093/ons/opx246 10.1177/019459988509300202 10.1016/S0194-5998(95)70101-X 10.1007/s00234-019-02358-y 10.1016/j.ijporl.2007.06.010 10.1007/s00381-007-0308-7 10.5606/Tr-ENT.2018.57966 10.1136/jnnp.66.6.764 10.1111/j.1399-0004.2007.00778.x
Child's Nervous System : ChNS : Official Journal of the I... Matsushima K, Kohno M et. al.

May 19th, 2022 - Sporadic vestibular schwannoma (VS) is rare in children in contrast to adults, and detailed investigations of case series of these patients using a single fixed protocol are scarce. This study presents our surgical experience of pediatric VSs with...

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Guidelines  8 results

Care of adults with neurofibromatosis type 1: a clinical practice resource of the Ameri...
https://doi.org/10.1038/gim.2018.28
Genetics in Medicine : Official Journal of the American C... Stewart DR, Korf BR et. al.

Jul 15th, 2018 - This practice resource is designed primarily as an educational resource for medical geneticists and other clinicians to help them provide quality medical services. Adherence to this practice resource is completely voluntary and does not necessaril...

Congress of Neurological Surgeons Systematic Review and Evidence-Based Guidelines on th...
https://doi.org/10.1093/neuros/nyx515
Neurosurgery Germano IM, Sheehan J et. al.

Jan 9th, 2018 - What are the indications for stereotactic radiosurgery (SRS) treatment vs observation for patients with intracanalicular vestibular schwannomas without evidence of radiographic progression? Level 3: If tinnitus is not observed at presentation, it ...

Congress of Neurological Surgeons Systematic Review and Evidence-Based Guidelines on Su...
https://doi.org/10.1093/neuros/nyx512
Neurosurgery Hadjipanayis CG, Carlson ML et. al.

Jan 9th, 2018 - What surgical approaches for vestibular schwannomas (VS) are best for complete resection and facial nerve (FN) preservation when serviceable hearing is present? There is insufficient evidence to support the superiority of either the middle fossa (...

Congress of Neurological Surgeons Systematic Review and Evidence-Based Guidelines on Em...
https://doi.org/10.1093/neuros/nyx516
Neurosurgery Van Gompel JJ, Agazzi S et. al.

Jan 9th, 2018 - Adults with histologically proven or suspected vestibular schwannomas with neurofibromatosis type 2 (NF2). What is the role of bevacizumab in the treatment of patients with vestibular schwannomas? Level 3: It is recommended that bevacizumab be adm...

Neurocognitive outcomes in neurofibromatosis clinical trials: Recommendations for the d...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5578356
Neurology Walsh KS, Janusz J et. al.

Aug 17th, 2016 - Neurofibromatosis type 1 (NF1) is associated with neurocognitive deficits that can impact everyday functioning of children, adolescents, and adults with this disease. However, there is little agreement regarding measures to use as cognitive endpoi...

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Drugs  2 results see all →

Clinicaltrials.gov  64 results

Natural History and Biospecimen Acquisition for Children and Adults With Rare Solid Tumors
https://clinicaltrials.gov/ct2/show/NCT03739827

May 20th, 2022 - Background: Rare tumors are defined as fewer than 150 incident cases per one million per year. Consequently, only 11 tumor types are common in U.S. adults (prostate, breast, lung/bronchus, colon, uterus, bladder, melanoma, rectum, ovary, non-Hodgk...

Medication Adherence in Children, Adolescents and Adults With Neurofibromatosis Type 1 (NF1) on Clinical Treatment Trials
https://clinicaltrials.gov/ct2/show/NCT03531814

May 20th, 2022 - Background: Neurofibromatosis type 1 (NF1) is a genetic disorder that affects approximately 1 in 3,500 individuals and is associated with a broad variety of symptoms and physical findings. Plexiform neurofibromas (PN) are histologically benign tum...

Natural History Study of Children and Adults With Neuroendocrine Neoplasms (NEN)s
https://clinicaltrials.gov/ct2/show/NCT04488263

May 20th, 2022 - Background: Neuroendocrine neoplasm (NENs) are divided into neuroendocrine tumors (NETs) and neuroendocrine carcinomas (NECs). These are rare malignancies occurring for example in the gastrointestinal tract, islets of the pancreas, lung, adrenal m...

Relationship Stressors in Parents of Children With Cancer or Neurofibromatosis Type 1 (NF1)
https://clinicaltrials.gov/ct2/show/NCT01702922

May 20th, 2022 - Background: Parents face numerous stressors when their child is diagnosed with cancer or NF1, each of which can strain a marriage/partnership. Marital/partner relationship dynamics are often not assessed or addressed when providing health care for...

Development and Validation of Patient Reported Outcome (PRO) Measures for Individuals With Neurofibromatosis 1 (NF1) and Plexiform Neurofibromas (pNFs)
https://clinicaltrials.gov/ct2/show/NCT02544022

May 13th, 2022 - Background: Neurofibromatosis 1 (NF1) is a genetic disease with multiple clinical manifestations, including plexiform neurofibromas (pNFs) that can cause pain and may significantly impact daily functioning and quality of life (QOL). Patient-report...

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News  65 results

Investigators Navigate the Complicated Treatment Landscape of Chemotherapy-Induced Neutropenia
https://www.onclive.com/view/investigators-navigate-the-complicated-treatment-landscape-of-chemotherapy-induced-neutropenia

Jan 19th, 2022 - Advances in the treatment of solid tumors and hematologic malignancies have resulted in the development of thera-peutic regimens that can be administered at various points in a patient’s care. However, as patients’ disease progresses, adverse effe...

Gastrointestinal Stromal Tumors Clinical Practice Guidelines (ESMO/EURACAN/GENTURIS, 2021)
https://www.medscape.com/viewarticle/963975

Dec 3rd, 2021 - Guidelines for the diagnosis, treatment, and follow-up of gastrointestinal stromal tumors (GISTs) were published in September 2021 by the European Society for Medical Oncology (ESMO), European Reference Network for Rare Adult Solid Cancers (EURACA...

Soft Nodule on the Forearm
http://www.mdedge.com/dermatology/article/247327/dermatopathology/soft-nodule-forearm
Syeda F. Absar, MD, MPH, Tammie C. Ferringer, MD

Oct 13th, 2021 - The Diagnosis: Schwannoma Schwannoma, also known as neurilemmoma, is a benign encapsulated neoplasm of the peripheral nerve sheath that presents as a subcutaneous nodule. 1 It also may present in the retroperitoneum, mediastinum, and viscera (eg, g.

Dr. Trent on the Utility of ctDNA to Understand Primary Mutations in GIST
https://www.onclive.com/view/dr-trent-on-the-utility-of-ctdna-to-understand-primary-mutations-in-gist

Oct 6th, 2021 - Jonathan C. Trent, MD, PhD, professor and associate director for Clinical Research at the Sylvester Comprehensive Cancer Center, University of Miami Health System, discusses the utility of circulating tumor DNA (ctDNA) to understand primary driver...

A female toddler presents with an itchy yellow nodule
https://www.mdedge.com/pediatrics/article/246672/dermatology/female-toddler-presents-itchy-yellow-nodule
MDedge Pediatrics; Lawrence Eichenfield, MD, Elana Kleinman

Oct 1st, 2021 - Juvenile xanthogranuloma (JXG) is a benign disorder presenting as firm, yellow-red skin papules or nodules, usually in infancy or early childhood. It derives its name based on its yellowish color and the histologic finding of lipid-filled histiocy.

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Patient Education  18 results see all →