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About 775 results

ALLMedicine™ Alopecia Areata Center

Research & Reviews  289 results

Using qualitative methods to establish the clinically meaningful threshold for treatmen...
https://doi.org/10.1007/s11136-022-03170-7
Quality of Life Research : an International Journal of Qu... Wyrwich KW, Kitchen H et. al.

Jul 13th, 2022 - Traditionally, appropriate anchors are used to investigate the amount of change on a clinician-reported outcome assessment that is meaningful to individual patients. However, novel qualitative methods involving input from disease state experts tog...

Comparative study between topical methotrexate 1% gel and minoxidil 5% gel in the treat...
https://doi.org/10.1111/dth.15696
Dermatologic Therapy; Toma DM, Atallah RB et. al.

Jul 8th, 2022 - Alopecia areata (AA) is an autoimmune disease that results in non-scarring hair loss. Topical minoxidil 5% gel and methotrexate (MTX) 1% gel are important modalities used in the treatment of many dermatological diseases. We aimed to evaluate the e...

Translational impact of omics studies in alopecia areata: recent advances and future pe...
https://doi.org/10.1080/1744666X.2022.2096590
Expert Review of Clinical Immunology; Basmanav FB, Betz RC

Jul 1st, 2022 - Alopecia areata (AA) is a non-scarring, hair loss disorder and a common autoimmune-mediated disease with an estimated lifetime risk of about 2%. To date, the treatment of AA is mainly based on suppression or stimulation of the immune response. Gen...

Analysis of alopecia areata surveys suggests a threshold for improved patient-reported ...
https://doi.org/10.1111/bjd.21696
The British Journal of Dermatology; Renert-Yuval Y, Correa da Rosa J et. al.

Jun 4th, 2022 - Although alopecia areata (AA) greatly impacts patients' quality of life (QoL), there is no adequate validation of AA-targeted QoL surveys in clinical trials, hindering sufficient representation of patient-reported outcomes. Better understanding of...

Impaired autophagy promotes hair loss in the C3H/HeJ mouse model of alopecia areata.
https://doi.org/10.1080/15548627.2022.2074104
Autophagy Gund R, Christiano AM

Jun 3rd, 2022 - Alopecia areata (AA) involves an aberrant immune attack on the hair follicle (HF), which leads to hair loss. Previous genetic data from our lab pointed to a connection between macroautophagy/autophagy and AA pathogenesis, and GWAS identified STX17...

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News  21 results

Baricitinib's Approval for Alopecia Areata: Considerations for Starting Patients on Treatment
https://www.medscape.com/viewarticle/976527

Jul 1st, 2022 - Dermatologists, who recently celebrated the US Food and Drug Administration's (FDA's) approval of the world's first oral systemic treatment for adults with severe alopecia areata (AA), are now looking ahead to the practicalities of getting the dru...

Baricitinib Recommended for Approval of Severe Alopecia Areata in Europe
https://www.medscape.com/viewarticle/974368

May 20th, 2022 - The European Medicines Agency's (EMA) Committee for Medicinal Products for Human Use (CHMP) has recommended approval of baricitinib, a Janus kinase (JAK) inhibitor, for the treatment of adults with severe alopecia areata (AA). The development, whi...

Oral Tofacitinib Produces Hair Regrowth in Children With Alopecia Areata
https://www.medscape.com/viewarticle/968410

Feb 14th, 2022 - Oral tofacitinib (Xeljanz), a JAK inhibitor, helped regrow hair in three quarters of pediatric patients with alopecia areata (AA) in a small study conducted at the University of Colorado and published in Pediatric Dermatology. The 11 pediatric pat...

Alopecia Tied to a Threefold Increased Risk for Dementia
https://www.medscape.com/viewarticle/962186

Nov 3rd, 2021 - Alopecia areata (AA), an autoimmune disease that causes hair loss, including baldness, has been linked to a significantly increased risk for dementia, new research shows. After controlling for an array of potential confounders, investigators found...

Pediatric Alopecia Areata in the US Has Increased Twofold Since 2009, Study Finds
https://www.medscape.com/viewarticle/954901

Jul 16th, 2021 - The prevalence of pediatric alopecia areata (AA) in the United States has increased twofold over the past decade and it disproportionately affects females and Hispanic children, according to results from the largest study to date on the topic. "Al...

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