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About 5,152 results

ALLMedicine™ Autosomal Dominant Polycystic Kidney Disease Center

Research & Reviews  2,517 results

Sequential Liver-Kidney Transplantation for Recurrent Liver Cysts Infection in a Patien...
https://doi.org/10.1016/j.transproceed.2021.02.018
Transplantation Proceedings; Issa Z, Ciccarelli O et. al.

Apr 16th, 2021 - Autosomal dominant polycystic kidney disease (ADPKD) is the most prevalent hereditary kidney disorder. Liver cysts are the most common extrarenal manifestation of the disease and usually remain asymptomatic. Liver cyst infection is rare, and its t...

The perioperative management of simultaneous bilateral nephrectomy with renal transplan...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8041388
Canadian Journal of Anaesthesia = Journal Canadien D'anes... Hofer RE, Kor TM et. al.

Apr 13th, 2021 - Bilateral nephrectomy is performed at times with renal transplantation. Though surgical indications and timing of these two procedures have been described, there are no large case series describing the anesthetic management of these cases. We soug...

Limitations and opportunities in the pharmacotherapy of ciliopathies.
https://doi.org/10.1016/j.pharmthera.2021.107841
Pharmacology & Therapeutics; Duong Phu M, Bross S et. al.

Mar 27th, 2021 - Ciliopathies are a family of rather diverse conditions, which have been grouped based on the finding of altered or dysfunctional cilia, potentially motile, small cellular antennae extending from the surface of postmitotic cells. Cilia-related diso...

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Guidelines  31 results

NIH Fact Sheets - Autosomal Dominant Polycystic Kidney Disease
https://www.report.nih.gov/nihfactsheets/ViewFactSheet.aspx?csid=29

Jun 29th, 2019 - Autosomal Dominant Polycystic Kidney Disease (ADPKD) resulted in end-stage renal disease (ESRD) by age 53, on average, and was responsible for 6 percent of ESRD cases in the U.S.

International consensus statement on the diagnosis and management of autosomal dominant...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7136168
Nature Reviews. Nephrology; Gimpel C, Bergmann C et. al.

May 23rd, 2019 - These recommendations were systematically developed on behalf of the Network for Early Onset Cystic Kidney Disease (NEOCYST) by an international group of experts in autosomal dominant polycystic kidney disease (ADPKD) from paediatric and adult nep...

Clinical practice guideline monitoring children and young people with, or at risk of de...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6489289
BMC Nephrology; Dudley J, Winyard P et. al.

May 1st, 2019 - Autosomal Dominant Polycystic Kidney Disease (ADPKD) is thought to affect about 1 in 1000 people in the UK. ADPKD causes a progressive decline in kidney function, with kidney failure tending to occur in middle age. Children and young people with A...

Imaging of Kidney Cysts and Cystic Kidney Diseases in Children: An International Working Gro...
https://pubs.rsna.org/doi/full/10.1148/radiol.2018181243

Dec 31st, 2018 - Kidney cysts can manifest as focal disease (simple and complex kidney cysts), affect a whole kidney (eg, multicystic dysplastic kidney or cystic dysplasia), or manifest as bilateral cystic disease (eg, autosomal recessive polycystic kidney disease.

KHA-CARI Autosomal Dominant Polycystic Kidney Disease Guideline: Imaging Approaches for...
https://doi.org/10.1016/j.semnephrol.2015.10.006
Seminars in Nephrology; Mai J, Lee VW et. al.

Dec 31st, 2015 - KHA-CARI Autosomal Dominant Polycystic Kidney Disease Guideline: Imaging Approaches for Diagnosis.|2016|Mai J,Lee VW,Lopez-Vargas P,Vladica P,|methods,diagnosis,diagnostic imaging,genetics,

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Drugs  2 results see all →

Clinicaltrials.gov  2,557 results

Sequential Liver-Kidney Transplantation for Recurrent Liver Cysts Infection in a Patien...
https://doi.org/10.1016/j.transproceed.2021.02.018
Transplantation Proceedings; Issa Z, Ciccarelli O et. al.

Apr 16th, 2021 - Autosomal dominant polycystic kidney disease (ADPKD) is the most prevalent hereditary kidney disorder. Liver cysts are the most common extrarenal manifestation of the disease and usually remain asymptomatic. Liver cyst infection is rare, and its t...

The perioperative management of simultaneous bilateral nephrectomy with renal transplan...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8041388
Canadian Journal of Anaesthesia = Journal Canadien D'anes... Hofer RE, Kor TM et. al.

Apr 13th, 2021 - Bilateral nephrectomy is performed at times with renal transplantation. Though surgical indications and timing of these two procedures have been described, there are no large case series describing the anesthetic management of these cases. We soug...

Limitations and opportunities in the pharmacotherapy of ciliopathies.
https://doi.org/10.1016/j.pharmthera.2021.107841
Pharmacology & Therapeutics; Duong Phu M, Bross S et. al.

Mar 27th, 2021 - Ciliopathies are a family of rather diverse conditions, which have been grouped based on the finding of altered or dysfunctional cilia, potentially motile, small cellular antennae extending from the surface of postmitotic cells. Cilia-related diso...

see more →

News  45 results

NIH Fact Sheets - Autosomal Dominant Polycystic Kidney Disease
https://www.report.nih.gov/nihfactsheets/ViewFactSheet.aspx?csid=29

Jun 29th, 2019 - Autosomal Dominant Polycystic Kidney Disease (ADPKD) resulted in end-stage renal disease (ESRD) by age 53, on average, and was responsible for 6 percent of ESRD cases in the U.S.

FDA Boxed Warnings Updates: October 2018
https://www.mdedge.com/fedprac/article/176365/fda-actions/fda-boxed-warnings-updates-october-2018/page/0/2

Oct 3rd, 2018 - PROGRAF (TACROLIMUS) Edited boxed warning, May 2018 Increased risk for developing serious infections and malignancies with PROGRAF or other immunosuppressants that may lead to hospitalization or death [(see Warnings and Precautions 5. 1,5.

The Latest on Tolvaptan and Kidney Function Decline in Later-Stage ADPKD Patients
https://www.medscape.com/viewarticle/889380

Dec 6th, 2017 - Autosomal dominant polycystic kidney disease (ADPKD) now is the fourth leading cause of end-stage renal disease (ESRD). ADPKD develops when the genes encoding polycystin 1 and polycystin 2 are disrupted, which leads to cyst development and eventua...

Leukemia Drug Bosutinib Shows Promise for Inherited Kidney Disease
https://www.medscape.com/viewarticle/885015

Aug 30th, 2017 - NEW YORK (Reuters Health) - The tyrosine kinase inhibitor bosutinib, approved for chronic myeloid leukemia, reduced kidney growth rate in patients with autosomal dominant polycystic kidney disease (ADPKD) in a phase 2 study. ADPKD affects up to 1 ...

Cancer Drug May Help in ADPKD
https://www.medpagetoday.com/nephrology/generalnephrology/67482

Aug 24th, 2017 - Action Points Note that this randomized trial suggested that bosutinib reduces the rate of cyst growth among patients with ADPKD. However, gastrointestinal side effects were significant, prompting discontinuation in nearly half of those treated. T...

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