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ALLMedicine™ Addison's Disease Center

Research & Reviews  225 results

Addison Disease
https://emedicine.medscape.com/article/116467-overview

Jan 13th, 2022 - Practice Essentials Addison disease (or Addison's disease) is adrenocortical insufficiency due to the destruction or dysfunction of the entire adrenal cortex. It affects glucocorticoid and mineralocorticoid function. The onset of disease usually o...

Molecular and clinical characterization of autoimmune polyendocrinopathy-candidiasis-ec...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8734050
Orphanet Journal of Rare Diseases; Setoodeh A, Panjeh-Shahi S et. al.

Jan 8th, 2022 - Autoimmune polyendocrinopathy-candidiasis-ectodermal dystrophy syndrome (APECED) is a rare autosomal recessive systemic autoimmune disease caused by mutations in the autoimmune regulator (AIRE) gene. Incidence of this genetic disorder is estimated...

Not the final diagnosis: from Addison's disease to POEMS syndrome: a case report and li...
https://doi.org/10.1177/03000605211066239
The Journal of International Medical Research; Xie X, Li R et. al.

Dec 22nd, 2021 - We report the case of a 47-year-old male patient with pigmentation of the head, face and hands, who was initially diagnosed as having primary adrenal insufficiency (Addison's disease). Laboratory testing, imaging and physical examination revealed ...

An autopsy case of unexpected death due to Addison's disease caused by adrenal tubercul...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8642993
European Journal of Medical Research; Zhao N, Gao Y et. al.

Dec 6th, 2021 - Adrenal tuberculosis is difficult to diagnose due to non-specific symptom. Unexpected death due to adrenal insufficiency after trauma surgery is rare. A 45-year-old man, who was admitted to hospital because of trauma to the right hand, died unexpe...

The natural history of 21-hydroxylase autoantibodies in autoimmune Addison's disease.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8052519
European Journal of Endocrinology; Wolff AB, Breivik L et. al.

Oct 20th, 2021 - The most common cause of primary adrenal failure (Addison's disease) in the Western world is autoimmunity characterized by autoantibodies against the steroidogenic enzyme 21-hydroxylase (CYP21A2, 21OH). Detection of 21OH-autoantibodies is currentl...

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Drugs  13 results see all →

Clinicaltrials.gov  3 results

Continuous Subcutaneous Hydrocortisone Infusion In Addison's Disease and Type 1 Diabetes
https://clinicaltrials.gov/ct2/show/NCT01840189

Feb 1st, 2017 - Treatment of Addison's disease includes glucocorticoid and mineralocorticoid replacement. Despite optimized therapy with these steroids, many patients suffer from impaired quality of life and increased mortality. The etiology of the premature deat...

Rescue of Steroidogenic Capacity in Adrenocortical Failure Study (RADS)
https://clinicaltrials.gov/ct2/show/NCT00753597

Feb 6th, 2013 - This is a pilot study of B lymphocyte depletion therapy in an attempt to salvage adrenal steroidogenic capacity in ten subjects with early autoimmune Addison's disease. During the first twelve weeks of treatment, additional glucocorticoid therapy ...

Exercise Capacity and Recovery in Addison's Disease
https://clinicaltrials.gov/ct2/show/NCT01657123

Aug 3rd, 2012 - Exposure to stress alters the activity of the adrenomedullary, adrenocortical and sympathetic nervous system, depending on the type and intensity of the stressor. Physical exercise represents a stress condition influencing many systems in the body...

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News  25 results

PD-1 Immunotherapies Induce Painless Thyroiditis in Patients With Metastatic Malignancies
https://www.onclive.com/view/pd-1-immunotherapies-induce-painless-thyroiditis-in-patients-with-metastatic-malignancies

Dec 20th, 2020 - Paul G. Walfish, CM, OOnt Treatment with programmed cell death 1 (PD-1) immunotherapy across various oncology clinical trials has been associated with the induction of painless thyroiditis, characterized by transient thyrotoxicosis and hypothyroi...

Fast Five Quiz: Can You Identify and Treat Hyperkalemia?
https://reference.medscape.com/viewarticle/849260_1

May 26th, 2020 - Hyperkalemia—serum potassium greater than approximately 5.0-5.5 mEq/L in adults—is associated with kidney disease, a diet high in potassium, and drugs that impair renal potassium excretion. It can also appear in infants or children with certain ge...

Fast Five Quiz: Can You Identify and Treat Hyperkalemia?
https://reference.medscape.com/viewarticle/849260

May 26th, 2020 - Hyperkalemia—serum potassium greater than approximately 5.0-5.5 mEq/L in adults—is associated with kidney disease, a diet high in potassium, and drugs that impair renal potassium excretion. It can also appear in infants or children with certain ge...

Malpractice Case: You're Liable, Even if Your EHR Malfunctions
https://www.staging.medscape.com/viewarticle/919804

Nov 4th, 2019 - Notwithstanding the usual suspects that hinder electronic health record (EHR) implementation—initial costs, interoperability problems, training burdens, and altered physician-patient dynamics—there's also the risk of a pure system malfunction. In ...

Malpractice Case: You're Liable, Even if Your EHR Malfunctions
https://www.medscape.com/viewarticle/919804

Nov 4th, 2019 - Notwithstanding the usual suspects that hinder electronic health record (EHR) implementation—initial costs, interoperability problems, training burdens, and altered physician-patient dynamics—there's also the risk of a pure system malfunction. In ...

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Patient Education  7 results see all →