About 580 results

ALLMedicine™ Adult-onset Still's Disease Center

Research & Reviews  228 results

Expression signature of inflammation-associated long non-coding RNAs in adult-onset Sti...
Clinical and Experimental Rheumatology; Yang CA, Chen PK et. al.

Sep 16th, 2021 - Adult-onset Still's disease (AOSD) is a rare and complex inflammatory disease with unclear immunopathogenesis. This study aims to investigate the expression signature of inflammation-associated long non-coding RNAs (lncRNAs) in AOSD and to evaluat...

Serum VEGF-C as an evaluation marker of disease activity in adult-onset Still's disease.
https://doi.org/10.1007/s00296-021-04978-1 10.1016/j.autrev.2014.01.058 10.1016/j.berh.2008.08.006 10.1038/s41584-018-0081-x 10.1002/art.1780290316 10.1002/art.1780280207 10.1186/s13075-017-1406-x 10.1080/14397595.2018.1514999 10.1136/annrheumdis-2019-215239 10.3390/ijms22147760 10.3389/fimmu.2021.674343 10.1016/j.gene.2015.01.023 10.1038/s41419-018-0570-5 10.1016/j.taap.2019.114702 10.1002/(sici)1097-0215(20000401)86:1<47::aid-ijc7>3.0.co;2-r 10.1136/ard.2008.094664 10.1016/j.intimp.2019.05.024 10.1080/08916934.2020.1755965 10.3899/jrheum.100247 10.1093/rheumatology/kew300 10.1093/rheumatology/keab023 10.1089/bio.2015.0104 10.1111/j.1399-0039.2008.01134.x 10.1038/sj.gene.6363922 10.1002/1529-0131(200107)44:7<1716::Aid-Art298>3.0.Co;2-I 10.1136/ard.2003.013680 10.1186/s13075-020-02200-4 10.3390/ijms19072012 10.1016/j.febslet.2004.08.036 10.1038/nrrheum.2017.205 10.1016/j.ccell.2017.10.003 10.1084/jem.172.6.1535 10.1038/nm0603-669 10.1210/edrv.18.1.0287 10.1074/jbc.271.2.736 10.1111/j.0022-202X.2004.22735.x 10.1016/j.intimp.2005.04.002 10.1016/s0736-5748(99)00048-9 10.1038/nri3787 10.1016/j.chom.2016.05.016 10.1038/nrrheum.2009.237 10.1016/j.coi.2020.10.014 10.1084/jem.20180861
Rheumatology International; Chen X, Hu QY et. al.

Sep 10th, 2021 - In view of the possible involvement of vascular endothelial growth factor-C (VEGF-C) in pathogenesis of adult-onset Still's disease (AOSD) based on our previous genome-wide association study (GWAS) results, the primary objective of this study, the...

Efficacy and safety of canakinumab in the treatment of adult-onset Still's disease: A s...
Seminars in Arthritis and Rheumatism; Cota-Arce JM, Cota J et. al.

Sep 9th, 2021 - Adult-onset Still's disease (AOSD) is a rare inflammatory disease, typically characterized by spiking fever, skin rash, and arthralgia or arthritis. Its conventional treatment includes NSAIDs and corticosteroids, and DMARDs as second-line therapy....

Synovial fluid cell count of 84 930/mm3 in adult-onset Still's disease.
BMJ Case Reports; Winberg C, Ladak K

Aug 26th, 2021 - In traditional teaching, synovial fluid cell counts over 50 000/mm3 are in keeping with septic or crystalline arthritis. We report a patient with adult-onset Still's disease (AOSD) and associated inflammatory arthritis whose synovial fluid cell co...

Adult-onset Still's disease following pneumococcal vaccination.
European Journal of Dermatology : EJD; Sato T, Takeo N et. al.

Aug 25th, 2021 - Adult-onset Still's disease following pneumococcal vaccination.|2021|Sato T,Takeo N,Matsuda-Hirose H,Abe K,Nishida H,|

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News  4 results

FDA Approves Canakinumab (Ilaris), First Drug for Adult-Onset Still's Disease

Jun 19th, 2020 - The Food and Drug Administration has expanded the indications for canakinumab (Ilaris) to include all patients with active Still's disease older than 2 years, adding adult-onset Still's disease (AOSD) to a previous approval for juvenile-onset Stil...

IL-6 for Adult Still's: A New Option?

Oct 14th, 2018 - Action Points Some clinical benefits were seen among patients with adult-onset Still's disease treated with tocilizumab (Actemra) in a small clinical trial, but the study's primary endpoint was not met. During the double-blind part of the trial, t...

Steroids and DMARDs Needed in Adult-Onset Still's

Aug 7th, 2010 - Action Points Explain to interested patients that in this study of patients with adult-onset Still's disease (aka systemic juvenile idiopathic arthritis), treatment with NSAIDs alone was usually not effective whereas steroids usually were. Note th...

Anakinra Promising in Pediatric Inflammation
Kate Johnson

Response to anakinra treatment was rapid and sustained in most patients with adult-onset Still's disease and in a “significant proportion” of patients with systemic-onset juvenile idiopathic arthritis, according to a study. The results suggest the.

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