ALLMedicine™ Minimal Change Disease Center
Research & Reviews 325 results
https://clinicaltrials.gov/ct2/show/NCT02639260
May 20th, 2022 - Background. ManNAc (N-acetyl D-mannosamine) is an uncharged monosaccharide that is the biologic precursor of N-acetyl neuraminic acid (Neu5Ac, sialic acid). Sialic acids are the negatively charged, terminal monosaccharides of carbohydrate chains t...
https://doi.org/10.1681/ASN.2021101396
Journal of the American Society of Nephrology : JASN; Zee J, Liu Q et. al.
May 18th, 2022 - Heterogeneity in disease course and treatment response among patients with MCD/FSGS necessitates a granular evaluation of kidney tissue features. This study aimed to identify histologic and ultrastructural descriptors of structural changes most pr...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9107780
Clinical and Experimental Nephrology; Nakagawa N, Maruyama S et. al.
May 16th, 2022 - Recent clinical reports indicate a correlation between new-onset and relapse of nephrotic syndrome (NS) following coronavirus 2019 (COVID-19) vaccination in patients with glomerular diseases. However, there are no reports of a nationwide survey on...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8996523
BMC Nephrology; Yu CY, Liu J et. al.
Apr 13th, 2022 - Minimal change disease (MCD) is a common cause of the nephrotic syndrome. Several studies have shown an increased incidence of cancer in patients with MCD. However, there are no reports on the association between MCD and gastrointestinal stromal t...
https://doi.org/10.1007/s40620-022-01279-z 10.2215/CJN.05000516 10.1007/s10157-012-0593-7 10.1097/MD.0000000000003179 10.1111/1747-0080.12444 10.1038/ki.1986.130 10.1007/s10157-013-0793-9 10.1155/2018/1657208 10.1186/s12882-018-0999-x 10.1007/s10157-020-01985-7 10.1007/s10157-018-1579-x 10.1007/s10157-019-01772-z 10.2215/CJN.12331213 10.1093/oxfordjournals.ndt.a027136 10.2215/CJN.01920219 10.1093/ndt/gfq668 10.1093/ndt/gfm523 10.1053/j.ajkd.2019.12.019 10.1007/s10157-020-01864-1 10.1053/j.ajkd.2003.10.024 10.1053/j.ajkd.2008.12.034 10.1007/s10157-015-1216-x 10.1016/j.kint.2018.11.008 10.1007/s10157-021-02098-5 10.1681/ASN.2005090922 10.1007/s10157-017-1443-4 10.1093/ndt/gfp422 10.1016/j.kint.2021.05.021 10.1097/FTD.0000000000000308 10.1007/s00467-018-3929-z
Journal of Nephrology; Yamamoto R, Imai E et. al.
Apr 3rd, 2022 - Minimal change disease (MCD) is characterized by a nephrotic syndrome usually steroid-sensitive and a high incidence of relapse of proteinuria. Previous cohort studies have reported conflicting results regarding the association between the time to...
Guidelines 1 results
https://doi.org/10.1016/j.kint.2021.05.015
Kidney International; Rovin BH, Adler SG et. al.
Sep 25th, 2021 - The Kidney Disease: Improving Global Outcomes (KDIGO) Clinical Practice Guideline for the Management of Glomerular Diseases is an update to the KDIGO 2012 guideline. The aim is to assist clinicians caring for individuals with glomerulonephritis (G...
Drugs 4 results see all →
Clinicaltrials.gov 7 results
https://clinicaltrials.gov/ct2/show/NCT02639260
May 20th, 2022 - Background. ManNAc (N-acetyl D-mannosamine) is an uncharged monosaccharide that is the biologic precursor of N-acetyl neuraminic acid (Neu5Ac, sialic acid). Sialic acids are the negatively charged, terminal monosaccharides of carbohydrate chains t...
https://clinicaltrials.gov/ct2/show/NCT05301829
Mar 31st, 2022 - Thrombin generation test will be performed prospectively in nephrotic patients with various diseases (Minimal Change Disease (MCD), Malignant Nephrosclerosis (MN), Focal Segmental GlomeruloSclerosis (FSGS), diabetic glomerulopathy…) at diagnosis, ...
https://clinicaltrials.gov/ct2/show/NCT04009668
Feb 2nd, 2022 - The researchers are testing adalimumab, a treatment which blocks tumor necrosis factor (TNF), to see if it changes levels of urine biomarker levels (TIMP1 and MCP1). The outcomes may help develop individualized treatment options for future patient...
https://clinicaltrials.gov/ct2/show/NCT03949972
Nov 22nd, 2021 - Idiopathic Nephrotic Syndrome is characterized by proteinuria, volume retention, hyperlipidemia, hypoalbuminemia. As Minimal Change Disease (MCD) represents by far the most prevalent underlying diagnosis in children older than 1 year, a kidney bio...
https://clinicaltrials.gov/ct2/show/NCT04369183
Dec 1st, 2020 - Various studies have been conducted to identify effective treatment strategies for primary focal segmental glomerulosclerosis (FSGS) and minimal change disease (MCD) so far. In the light of these studies, corticosteroids and calcineurin inhibitors...
News 5 results
https://www.medscape.com/viewarticle/954056
Jul 1st, 2021 - NEW YORK (Reuters Health) - Adults with primary nephrotic syndrome (NS) had close to a 20 times greater risk of developing kidney failure and higher risks of several cardiovascular diseases and death compared to those without NS in a large analysi...
https://www.medscape.com/viewarticle/904069
Feb 24th, 2020 - First-line Therapy for Nephrotic Syndrome: A Comparison Idiopathic nephrotic syndrome is the most common disorder of glomerular function in pediatrics.[1] Approximately 40% of children diagnosed with idiopathic nephrotic syndrome will have a relap...
https://www.medscape.com/viewarticle/909227
Feb 27th, 2019 - FR, SD, and SR Nephrotic Syndrome: A Therapeutic Challenge Nearly two decades into the 21st century and steroids remain the first-line agent for many glomerulonephritides. In particular, steroids continue to have a dominant therapeutic role in tre...
https://www.medscape.com/viewarticle/459180
Abstract and Introduction Abstract Idiopathic childhood nephrotic syndrome generally has a favorable long-term prognosis. Prompt administration of and improved guidelines for monitoring therapy have decreased morbidity and mortality. The treatment...
https://www.medscape.com/viewarticle/958098
The immunologic response following several varieties of vaccination (especially meningococcal C conjugate vaccines) has been described as a potential trigger for the development of nephrotic syndrome (NS).[1,2] Coronavirus disease 2019 (COVID-19) ...
