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About 100 results

ALLMedicine™ Autoimmune Pulmonary Alveolar Proteinosis Center

Research & Reviews  35 results

Autoimmune pulmonary alveolar proteinosis: a discrepancy between symptoms and CT findings.
https://doi.org/10.1016/S0140-6736(21)01254-X
Lancet (London, England); Hawkins P, Chawke L et. al.

Jul 19th, 2021 - Autoimmune pulmonary alveolar proteinosis: a discrepancy between symptoms and CT findings.|2021|Hawkins P,Chawke L,Cormican L,Wikenheiser-Brokamp KA,Fabre A,|

Autoimmune pulmonary alveolar proteinosis successfully treated with lung lavage in an a...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8268574
Journal of Medical Case Reports; Alasiri AM, Alasbali RA et. al.

Jul 10th, 2021 - Pulmonary alveolar proteinosis is a rare interstitial lung disease characterized by accumulating surfactant materials in the alveoli. The autoimmune form is by far the most common in adults, while in the pediatric age group, the vast majority of c...

Increased Efficacy of Whole Lung Lavage Treatment in Alveolar Proteinosis Using a New M...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8219085
Journal of Bronchology & Interventional Pulmonology; Grutters LA, Smith EC et. al.

Jun 22nd, 2021 - Autoimmune pulmonary alveolar proteinosis is an ultra-rare pulmonary disease. Whole lung lavage (WLL) is considered the gold standard therapy. We report a protocol for a new modified lavage technique (nMLT) in which controlled repetitive manual hy...

Autoimmune Pulmonary Alveolar Proteinosis: Evidence of the pathogenicity of GM-CSF anti...
https://doi.org/10.1164/rccm.202101-0073IM
American Journal of Respiratory and Critical Care Medicine; Le Gal A, Chabrol A et. al.

Jun 16th, 2021 - Autoimmune Pulmonary Alveolar Proteinosis: Evidence of the pathogenicity of GM-CSF antibodies.|2021|Le Gal A,Chabrol A,Brun AL,Fraboulet S,Couderc LJ,|

Expression profiles and potential functions of long noncoding RNAs and mRNAs in autoimm...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8064141
Aging Yang Y, Xu W et. al.

Apr 7th, 2021 - Autoimmune pulmonary alveolar proteinosis (APAP) is a rare lung disease that may be associated with surfactant overaccumulation. To assess the function of long noncoding RNAs (lncRNAs) in APAP, we performed microarray analyses to identify differen...

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Clinicaltrials.gov  5 results

Pioglitazone Therapy of Autoimmune Pulmonary Alveolar Proteinosis Autoimmune Pulmonary Alveolar Proteinosis
https://clinicaltrials.gov/ct2/show/NCT03231033

Jan 18th, 2020 - PAP is a rare syndrome of surfactant accumulation and resulting hypoxemic respiratory failure that occurs in multiple diseases that can be classified on the basis of pathogenesis into three groups: primary PAP (caused by disruption of GM-CSF signa...

Efficacy and Safety of Inhaled Molgramostim (rhGM-CSF) in Autoimmune Pulmonary Alveolar Proteinosis (aPAP)
https://clinicaltrials.gov/ct2/show/NCT02702180

Apr 12th, 2018 - The trial is a randomised, double-blind, placebo-controlled multicentre clinical trial investigating efficacy and safety of inhaled molgramostim (rhGM-CSF) in autoimmune pulmonary alveolar proteinosis (aPAP) patients. The primary objective is effi...

Sequential Therapy With WLL/Inhaling GM-CSF for Autoimmune Pulmonary Alveolar Proteinosis
https://clinicaltrials.gov/ct2/show/NCT03316651

Oct 20th, 2017 - The purpose of the study is to evaluate the effectiveness of the sequential therapy with whole lung Lavage (WLL)/inhaling granulocyte-macrophage colony stimulating factor, compared to WLL only, for adult patients with severe autoimmune pulmonary a...

Evaluation of a Single Dose of Inhaled Sargramostim in Patients With Autoimmune Pulmonary Alveolar Proteinosis
https://clinicaltrials.gov/ct2/show/NCT03006146

Oct 12th, 2017 - PAP is a rare syndrome of surfactant accumulation and resulting hypoxemic respiratory failure that occurs in a number of diseases classified pathogenically into three groups: primary PAP (caused by disruption of GM-CSF signaling - autoimmune PAP, ...

Whole Lung Lavage (WLL)/Inhaled Granulocyte-macrophage Colony-stimulating Factor (GM-CSF) in Autoimmune Pulmonary Alveolar Proteinosis (PAP)
https://clinicaltrials.gov/ct2/show/NCT00901511

Background: Pulmonary alveolar proteinosis (PAP) is a rare disorder characterized by accumulation of lipoproteinaceous material within alveolar spaces, leading to respiratory failure. Whole lung lavage (WLL) is the current therapeutic option, but ...

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