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ALLMedicine™ Allergic Bronchopulmonary Aspergillosis Center

Research & Reviews  270 results

A Study to Evaluate the Efficacy and Safety of Dupilumab in Participants With Allergic Bronchopulmonary Aspergillosis (ABPA) (LIBERTY ABPA AIRED)
https://clinicaltrials.gov/ct2/show/NCT04442269

Aug 10th, 2022 - The primary objective of the study is to evaluate the efficacy of dupilumab on the annualized rate of exacerbations in participants with Allergic Bronchopulmonary Aspergillosis (ABPA). The secondary objectives of the study are: To evaluate the eff...

Biologic drugs in treating allergic bronchopulmonary aspergillosis in patients with cys...
https://doi.org/10.1183/16000617.0011-2022
European Respiratory Review : an Official Journal of the ... Manti S, Giallongo A et. al.

Jul 28th, 2022 - Aspergillus fumigatus is a common saprophytic fungus causing allergic bronchopulmonary aspergillosis (ABPA) in patients with cystic fibrosis (CF). The recommended first-line treatment for ABPA is oral steroids, followed by antifungal therapy. Howe...

Can dose reduction be made in patients with allergic bronchopulmonary aspergillosis rec...
https://doi.org/10.23822/EurAnnACI.1764-1489.261
European Annals of Allergy and Clinical Immunology; Korkmaz ET, Aydın O et. al.

Jul 20th, 2022 - Objective. To reduce the omalizumab dose in patients with allergic bronchopulmonary aspergillosis (ABPA) who were on long-term omalizumab treatment. Methods. Once asthma was controlled, two approaches were used to reduce total monthly omalizumab d...

Hypereosinophilic Syndrome
https://emedicine.medscape.com/article/202030-print

Jul 13th, 2022 - Practice Essentials Hypereosinophilic syndrome (HES) is a myeloproliferative disorder (MPD) characterized by persistent eosinophilia that is associated with damage to multiple organs.[1, 2, 3, 4, 5, 6, 7] HES is classified into primary (clonal) HE...

Hypereosinophilic Syndrome
https://emedicine.medscape.com/article/202030-overview

Jul 13th, 2022 - Practice Essentials Hypereosinophilic syndrome (HES) is a myeloproliferative disorder (MPD) characterized by persistent eosinophilia that is associated with damage to multiple organs. [1, 2, 3, 4, 5, 6, 7] HES is classified into primary (clonal) H...

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Drugs  13 results see all →

Clinicaltrials.gov  26 results

A Study to Evaluate the Efficacy and Safety of Dupilumab in Participants With Allergic Bronchopulmonary Aspergillosis (ABPA) (LIBERTY ABPA AIRED)
https://clinicaltrials.gov/ct2/show/NCT04442269

Aug 10th, 2022 - The primary objective of the study is to evaluate the efficacy of dupilumab on the annualized rate of exacerbations in participants with Allergic Bronchopulmonary Aspergillosis (ABPA). The secondary objectives of the study are: To evaluate the eff...

Oral Itraconazole Versus Combination of Systemic Glucorticoids and Oral Itraconazole in CPA-ABPA Overlap Syndrome
https://clinicaltrials.gov/ct2/show/NCT05444946

Jul 6th, 2022 - Aspergillus causes a variety of pulmonary disorders depending on the host immunity. In immunocompetent hosts, it can cause allergic diseases, the prototype being allergic bronchopulmonary aspergillosis (ABPA). In immunosuppressed host, it causes l...

A Randomized Controlled Trial to Compare the Clinical Outcomes With Six Months of Therapy With Oral Itraconazole Versus Oral Voriconazole for Management of Treatment naïve Subjects With Chronic Pul...
https://clinicaltrials.gov/ct2/show/NCT04824417

Jun 13th, 2022 - Aspergillus is a saprophytic fungus which is present normally in our surroundings and causes a large number of pulmonary diseases spreading through inhalational route. The spectrum of disease caused by aspergillus spp. is wide with the manifestati...

Immune Profiles in CF Fungal Infection
https://clinicaltrials.gov/ct2/show/NCT04476758

May 27th, 2022 - While bacteria are predominant agents in CF lung disease, fungi are often isolated in both sputum and bronchoalveolar lavage fluid (BAL), yet their role in CF is not fully understood. Fungal infection in CF has a wide spectrum of presentations, va...

Characterizing Asthma Sputum Elasticity in the UCSF Severe Asthma Research Program
https://clinicaltrials.gov/ct2/show/NCT02103348

Feb 1st, 2022 - Asthma is a heterogeneous disease characterized by airway hyperreactivity and chronic airway inflammation. Published literature from the last few years has shown that asthma does not behave like a single disease but is more of a syndrome with vast...

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News  6 results

Five Things You Need to Know About Bronchiectasis
https://www.medscape.com/viewarticle/955069

Jul 22nd, 2021 - Bronchiectasis is a chronic condition characterised by symptoms of persistent or recurrent bronchial sepsis caused by irreversible damage to and dilation of the bronchi.[1] The key principles of the diagnosis and management of bronchiectasis were ...

Fast Five Quiz: How Much Do You Know About Asthma?
https://reference.medscape.com/viewarticle/846001_4

Jun 4th, 2019 - Blood eosinophilia > 4% or 300-400 cells/μL supports the diagnosis of asthma, but the absence of this finding is not exclusionary. Total serum immunoglobulin E levels > 100 IU/mL are frequently observed in patients experiencing allergic reactions,...

Adult bronchiectasis, asthma therapy, frailty in ILD
https://www.mdedge.com/chestphysician/article/158061/society-news/adult-bronchiectasis-asthma-therapy-frailty-ild

Feb 6th, 2018 - Clinical Research New guidelines for adult bronchiectasis Clinically significant bronchiectasis is a combination of radiologic bronchial dilatation with clinical symptoms. Guidelines on management of adult bronchiectasis were recently published (E.

Management of Asthma in the Military
https://www.mdedge.com/fedprac/article/135491/pulmonology/management-asthma-military
Capt Frederic A. Rawlins III, DO, LTC Jacob F. Collen, MD et. al.

Apr 10th, 2017 - Asthma is a chronic inflammatory disorder of the airways that leads to airflow obstruction and bronchial hyperresponsiveness. Clinical features of asthma include episodic cough, wheeze, and dyspnea, which may resolve with avoidance of triggers or.

European societies issue aspergillosis diagnosis, management guidelines
https://www.mdedge.com/chestphysician/article/105429/infectious-diseases/european-societies-issue-aspergillosis-diagnosis
Neil Osterweil, MDedge News

Dec 23rd, 2015 - European respiratory disease and infectious disease specialists have banded together to issue new clinical guidelines on the diagnosis and management of an uncommon but serious problem: chronic pulmonary aspergillosis (CPA). Pulmonary infections w.

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Patient Education  5 results see all →