ALLMedicine™ Alpha-1 Antitrypsin Deficiency Center
Research & Reviews 325 results
https://doi.org/10.1080/17476348.2023.2174973
Expert Review of Respiratory Medicine; McElvaney OF, Fraughen DD et. al.
Mar 11th, 2023 - Alpha1 antitrypsin deficiency (AATD), a common hereditary disorder affecting mainly lungs, liver and skin has been the focus of some of the most exciting therapeutic approaches in medicine in the past 5 years. In this review, we discuss the therap...
https://doi.org/10.1016/j.transproceed.2023.01.004
Transplantation Proceedings; Terada Y, Hachem RR et. al.
Feb 14th, 2023 - Pulmonary carcinoid tumorlet (PCT) is defined as small proliferation of neuroendocrine cells that invade the adjacent basement membrane. It is often associated with chronic pulmonary inflammatory processes. However, the characteristics of PCT in e...
https://clinicaltrials.gov/ct2/show/NCT01097954
Feb 13th, 2023 - Exercise induced bronchospasm (EIB), also known as exercise induced asthma (EIA) is a transient obstruction to airflow triggered by exertion. It is now a well known identity, center of discussion in recent years, particularly in the athletes' worl...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9885054
BMC Health Services Research; Calle Rubio M, López-Campos JL et. al.
Feb 1st, 2023 - Patients with alpha-1 antitrypsin deficiency (AATD), commonly categorized as a rare disease, have been affected by the changes in healthcare management brought about by COVID-19. This study's aim was to identify the changes that have taken place i...
https://clinicaltrials.gov/ct2/show/NCT05195853
Dec 30th, 2022 - Lung transplantation is the curative treatment for end-stage respiratory failure involving highly selected patients. In 2018, the International Transplant Registry counts 69200 lung transplants among 260 transplant centers. Between 2010 and June 2...
Guidelines 3 results
https://doi.org/10.1016/j.clinre.2021.101768
Clinics and Research in Hepatology and Gastroenterology; Sobesky R, Guillaud O et. al.
Aug 1st, 2021 - Rare genetic liver diseases can result in multi-systemic damage, which may compromise the patient's prognosis. Wilson's disease and alpha-1 antitrypsin deficiency must be investigated in any patient with unexplained liver disease. Cystic fibrosis ...
https://doi.org/10.1038/ajg.2016.517
The American Journal of Gastroenterology; Kwo PY, Cohen SM et. al.
Dec 21st, 2016 - Clinicians are required to assess abnormal liver chemistries on a daily basis. The most common liver chemistries ordered are serum alanine aminotransferase (ALT), aspartate aminotransferase (AST), alkaline phosphatase and bilirubin. These tests sh...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3373286
Canadian Respiratory Journal; Marciniuk DD, Hernandez P et. al.
Apr 27th, 2012 - Alpha-1 antitrypsin (A1AT) functions primarily to inhibit neutrophil elastase, and deficiency predisposes individuals to the development of chronic obstructive pulmonary disease (COPD). Severe A1AT deficiency occurs in one in 5000 to one in 5500 o...
Clinicaltrials.gov 35 results
https://clinicaltrials.gov/ct2/show/NCT01097954
Feb 13th, 2023 - Exercise induced bronchospasm (EIB), also known as exercise induced asthma (EIA) is a transient obstruction to airflow triggered by exertion. It is now a well known identity, center of discussion in recent years, particularly in the athletes' worl...
https://clinicaltrials.gov/ct2/show/NCT05195853
Dec 30th, 2022 - Lung transplantation is the curative treatment for end-stage respiratory failure involving highly selected patients. In 2018, the International Transplant Registry counts 69200 lung transplants among 260 transplant centers. Between 2010 and June 2...
https://clinicaltrials.gov/ct2/show/NCT02014415
Dec 14th, 2022 - Alpha-1 Antitrypsin Deficiency (AATD) is a genetic disorder resulting in a low level of a protein called alpha-1 antitrypsin (AAT). This deficiency can cause life-threatening liver disease and/or lung disease at various ages. Some patients experie...
https://clinicaltrials.gov/ct2/show/NCT01148550
Nov 22nd, 2022 - This study will be conducted as part of the NIH-supported Childhood Liver Disease Research and Education Network (ChiLDREN). ChiLDREN is investigating rare cholestatic liver diseases of childhood: alpha-1 antitrypsin deficiency (A1AT), Alagille's ...
https://clinicaltrials.gov/ct2/show/NCT00500123
Nov 7th, 2022 - Genetic testing for alpha-1 antitrypsin deficiency is sometimes delayed despite established testing indications. All genetic tests have risks and possible benefits. The ACT study evaluates the population demographics, reasons for testing, and outc...
News 47 results
https://www.mdedge.com/familymedicine/article/257727/pulmonology/copd-inhaler-therapy-path-success
MDedge Family Medicine; Michael Arnold, DO, FAAFP, Cate Vordtriede, PharmD, BCPS et. al.
Sep 12th, 2022 - Managing chronic obstructive pulmonary disease (COPD) presents a significant challenge to busy clinicians in many ways, especially when one is approaching the long list of inhaled pharmaceutical agents with an eye toward a cost-effective, patient-.
https://www.medscape.com/viewarticle/973787
May 11th, 2022 - Screening for chronic obstructive pulmonary disease (COPD) in asymptomatic adults has no net benefit, according to a U.S. Preventive Services Task Force (USPSTF) reassessment of its 2016 screening recommendations. The new recommendation is in line...
https://www.mdedge.com/chestphysician/article/254452/copd/copd-screening-asymptomatic-adults-uspstf-weighs-again
Mark S. Lesney, PhD, MDedge News
May 10th, 2022 - Screening for chronic obstructive pulmonary disease (COPD) in asymptomatic adults has no net benefit, according to a U. S.
https://www.medpagetoday.com/infectiousdisease/covid19/93049
Jun 11th, 2021 - Note that some links may require registration or subscription. Here we go again. As cruise lines struggle to recover from COVID-19, two passengers aboard a Royal Caribbean ship tested positive for coronavirus; all crew and passengers over 16 were ...
https://www.onclive.com/view/hcc-etiologic-risk-factors-and-global-prevalence
Apr 2nd, 2021 - Minsig Choi, MD: What are the etiology risk factors in the development of hepatocellular cancer? We all know that hepatocellular cancer or liver cancer is caused by a chronic irritation or inflammations. Usually the most common causes of this irri...