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About 7,338 results

ALLMedicine™ Acromegaly Center

Research & Reviews  3,491 results

GH-induced LH hyporesponsiveness as a potential mechanism for hypogonadism in male pati...
https://doi.org/10.1507/endocrj.EJ20-0596
Endocrine Journal; Nishio R, Takeshita A et. al.

Apr 12th, 2021 - Male patients with acromegaly frequently have hypogonadism. However, whether excess GH affects gonadal function remains unclear. We retrospectively compared clinical features affecting total testosterone (TT) and free testosterone (FT) levels betw...

Management of endocrine disease: Etiology and outcome of acromegaly in patients with a ...
https://doi.org/10.1530/EJE-20-1448
European Journal of Endocrinology; Hage M, Janot C et. al.

Apr 8th, 2021 - To gain more insight on the pathogenesis of somatotroph pituitary adenomas, recent studies have focused on a subgroup of patients with acromegaly displaying a paradoxical growth hormone (GH) response during oral glucose tolerance test (OGTT). The ...

Autophagy in normal pituitary and pituitary tumor cells and its potential role in the a...
https://doi.org/10.1007/s11154-021-09649-x 10.1101/gad.1599207 10.1038/nature06639 10.1016/j.bbamcr.2009.01.006 10.1038/ncb2788 10.1002/med.21531 10.1530/ERC-15-0042 10.3390/ijms19113466 10.1016/j.cell.2010.01.028 10.4161/auto.19496 10.1530/JME-13-0241 10.1210/en.2015-1777 10.1007/978-981-15-4272-5_12 10.1016/0026-0495(82)90184-6 10.1111/j.1365-2265.1987.tb00796.x 10.1055/s-0042-107243 10.18632/oncotarget.5744 10.1002/jcb.29281 10.3389/fendo.2019.00690 10.1016/j.toxlet.2018.05.041 10.1007/s11154-020-09564-7 10.1016/j.ecl.2007.10.013 10.1159/000054651 10.1007/s11102-010-0269-9 10.1016/bs.pmbts.2015.10.015 10.1371/journal.pone.0036411 10.1007/s11102-009-0169-z 10.1530/EJE-09-0372 10.1210/jc.2017-00142 10.1080/14656566.2016.1199687 10.1126/science.179.4068.77 10.1111/j.1471-4159.2004.02402.x 10.1006/frne.1999.0183 10.1016/j.pharmthera.2015.05.007 10.1007/s11102-020-01028-0 10.1167/iovs.16-19285 10.1016/j.phrs.2017.09.022 10.1038/srep42701 10.1016/j.transproceed.2013.02.112 10.1159/000493413 10.1530/EJE-17-0796 10.1007/s11154-019-09531-x 10.3389/fendo.2020.608422 10.1210/jc.2015-3653 10.1007/s11154-020-09588-z 10.1210/jc.2014-2468 10.1111/j.1365-2265.2006.02562.x 10.1007/s11102-019-01025-y 10.1080/15548627.2017.1328347 10.1016/j.canlet.2019.05.043 10.1210/jc.2017-00627 10.3389/fendo.2018.00318 10.1038/srep12291 10.3892/mmr.2015.4255 10.1385/EP:16:2:123 10.1385/EP:16:2:115 10.1158/0008-5472.CAN-05-1189 10.1042/BCJ20160780 10.3389/fendo.2019.00007
Reviews in Endocrine & Metabolic Disorders; Tulipano G, Giustina A

Apr 6th, 2021 - Autophagy is an evolutionary conserved process for the self-degradation and recycling of cellular components in the cytoplasm. It is involved in both physiological and pathological conditions. In detail, the term "autophagy" refers to intracellula...

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Guidelines  13 results

Italian Society for the Study of Diabetes (SID)/Italian Endocrinological Society (SIE) ...
https://doi.org/10.1016/j.numecd.2016.02.001
Nutrition, Metabolism, and Cardiovascular Diseases : NMCD; Baroni MG, Giorgino F et. al.

Feb 25th, 2016 - Hyperglycemia is a common feature associated with states of increased growth hormone secretion and glucocorticoid levels. The purpose of these guidelines is to assist clinicians and other health care providers to take evidence-based therapeutic de...

Italian Society for the Study of Diabetes (SID)/Italian Endocrinological Society (SIE) ...
https://doi.org/10.1007/s40618-015-0404-6
Journal of Endocrinological Investigation; Baroni MG, Giorgino F et. al.

Dec 31st, 2015 - Hyperglycemia is a common feature associated with states of increased growth hormone secretion and glucocorticoid levels. The purpose of these guidelines is to assist clinicians and other health care providers to take evidence-based therapeutic de...

Acromegaly: an endocrine society clinical practice guideline.
https://doi.org/10.1210/jc.2014-2700
The Journal of Clinical Endocrinology and Metabolism; Katznelson L, Laws ER et. al.

Oct 30th, 2014 - The aim was to formulate clinical practice guidelines for acromegaly. The Task Force included a chair selected by the Endocrine Society Clinical Guidelines Subcommittee (CGS), five experts in the field, and a methodologist. The authors received no...

Expert consensus document: A consensus on the medical treatment of acromegaly.
https://doi.org/10.1038/nrendo.2014.21
Nature Reviews. Endocrinology; Giustina A, Chanson P et. al.

Feb 25th, 2014 - In March 2013, the Acromegaly Consensus Group met to revise and update guidelines for the medical treatment of acromegaly. The meeting comprised experts skilled in the medical management of acromegaly. The group considered treatment goals covering...

American Association of Clinical Endocrinologists medical guidelines for clinical pract...
https://www.ncbi.nlm.nih.gov/pubmed/21846616
Endocrine Practice : Official Journal of the American Col... Katznelson L, Atkinson JL et. al.

Aug 23rd, 2011 - American Association of Clinical Endocrinologists medical guidelines for clinical practice for the diagnosis and treatment of acromegaly--2011 update.|2011|Katznelson L,Atkinson JL,Cook DM,Ezzat SZ,Hamrahian AH,|diagnosis,therapy,standards,trends,...

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Drugs  35 results see all →

Clinicaltrials.gov  3,659 results

GH-induced LH hyporesponsiveness as a potential mechanism for hypogonadism in male pati...
https://doi.org/10.1507/endocrj.EJ20-0596
Endocrine Journal; Nishio R, Takeshita A et. al.

Apr 12th, 2021 - Male patients with acromegaly frequently have hypogonadism. However, whether excess GH affects gonadal function remains unclear. We retrospectively compared clinical features affecting total testosterone (TT) and free testosterone (FT) levels betw...

Management of endocrine disease: Etiology and outcome of acromegaly in patients with a ...
https://doi.org/10.1530/EJE-20-1448
European Journal of Endocrinology; Hage M, Janot C et. al.

Apr 8th, 2021 - To gain more insight on the pathogenesis of somatotroph pituitary adenomas, recent studies have focused on a subgroup of patients with acromegaly displaying a paradoxical growth hormone (GH) response during oral glucose tolerance test (OGTT). The ...

Autophagy in normal pituitary and pituitary tumor cells and its potential role in the a...
https://doi.org/10.1007/s11154-021-09649-x 10.1101/gad.1599207 10.1038/nature06639 10.1016/j.bbamcr.2009.01.006 10.1038/ncb2788 10.1002/med.21531 10.1530/ERC-15-0042 10.3390/ijms19113466 10.1016/j.cell.2010.01.028 10.4161/auto.19496 10.1530/JME-13-0241 10.1210/en.2015-1777 10.1007/978-981-15-4272-5_12 10.1016/0026-0495(82)90184-6 10.1111/j.1365-2265.1987.tb00796.x 10.1055/s-0042-107243 10.18632/oncotarget.5744 10.1002/jcb.29281 10.3389/fendo.2019.00690 10.1016/j.toxlet.2018.05.041 10.1007/s11154-020-09564-7 10.1016/j.ecl.2007.10.013 10.1159/000054651 10.1007/s11102-010-0269-9 10.1016/bs.pmbts.2015.10.015 10.1371/journal.pone.0036411 10.1007/s11102-009-0169-z 10.1530/EJE-09-0372 10.1210/jc.2017-00142 10.1080/14656566.2016.1199687 10.1126/science.179.4068.77 10.1111/j.1471-4159.2004.02402.x 10.1006/frne.1999.0183 10.1016/j.pharmthera.2015.05.007 10.1007/s11102-020-01028-0 10.1167/iovs.16-19285 10.1016/j.phrs.2017.09.022 10.1038/srep42701 10.1016/j.transproceed.2013.02.112 10.1159/000493413 10.1530/EJE-17-0796 10.1007/s11154-019-09531-x 10.3389/fendo.2020.608422 10.1210/jc.2015-3653 10.1007/s11154-020-09588-z 10.1210/jc.2014-2468 10.1111/j.1365-2265.2006.02562.x 10.1007/s11102-019-01025-y 10.1080/15548627.2017.1328347 10.1016/j.canlet.2019.05.043 10.1210/jc.2017-00627 10.3389/fendo.2018.00318 10.1038/srep12291 10.3892/mmr.2015.4255 10.1385/EP:16:2:123 10.1385/EP:16:2:115 10.1158/0008-5472.CAN-05-1189 10.1042/BCJ20160780 10.3389/fendo.2019.00007
Reviews in Endocrine & Metabolic Disorders; Tulipano G, Giustina A

Apr 6th, 2021 - Autophagy is an evolutionary conserved process for the self-degradation and recycling of cellular components in the cytoplasm. It is involved in both physiological and pathological conditions. In detail, the term "autophagy" refers to intracellula...

see more →

News  125 results

Fast Five Quiz: Test Your Knowledge of Acromegaly
https://reference.medscape.com/viewarticle/875763_6

Sep 15th, 2020 - Answer 5/5 Which of the following is accurate regarding treatment of acromegaly? Your peers chose: Pharmacologic therapy is the first-line treatment for acromegaly 0% Radiation therapy is routinely indicated for most patients with acromegaly 0% Fo...

Fast Five Quiz: Test Your Knowledge of Acromegaly
https://reference.medscape.com/viewarticle/875763_2

Sep 15th, 2020 - Causes of excess IGF-I action can be divided into the following three categories: Release of primary GH excess from the pituitary Increased GHRH secretion or hypothalamic dysregulation Hypothetically, the excessive production of IGF-binding protei...

Fast Five Quiz: Test Your Knowledge of Acromegaly
https://reference.medscape.com/viewarticle/875763

Sep 15th, 2020 - Gigantism refers to abnormally high linear growth due to excessive action of insulin-like growth factor I (IGF-I) while the epiphyseal growth plates are open during childhood. Acromegaly is the same disorder of IGF-I excess but occurs after the gr...

Fast Five Quiz: Test Your Knowledge of Acromegaly
https://reference.medscape.com/viewarticle/875763_3

Sep 15th, 2020 - Gigantism is extremely rare, with approximately 100 reported cases to date. Acromegaly is more common than gigantism, with an incidence of 3-4 cases per million people per year and a prevalence of 60 cases per million population. A claims-based an...

FDA Approves First Oral Somatostatin Analog for Acromegaly
https://www.staging.medscape.com/viewarticle/933087

Jun 28th, 2020 - The US Food and Drug Administration (FDA) has approved oral octreotide (Mycapssa, Chiasma) delayed-release capsules for the long-term maintenance treatment of patients with acromegaly who previously responded to and tolerated octreotide or lanreot...

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Patient Education  15 results see all →