×
About 180 results

ALLMedicine™ Adenosine Deaminase Deficiency Center

Research & Reviews  87 results

Successful engraftment of haploidentical stem cell transplant with post-transplantation...
https://doi.org/10.1111/petr.13954
Pediatric Transplantation REFERENCES; Medina D, Aristizabal AM et. al.

Dec 29th, 2020 - SCID are characterized by an imbalance in cellular and humoral immunity. Enzyme ADA deficiency represents from 10% to 15% of the SCID. This generates diminished maturation of the cell precursors. Treatments include enzyme replacement therapy, allo...

Outcomes of 3 patients with adenosine deaminase deficiency on long-term enzyme replacem...
https://doi.org/10.1016/j.anai.2020.12.008
Annals of Allergy, Asthma & Immunology : Official Publica... Gans MD, Bernstein L et. al.

Dec 28th, 2020 - Outcomes of 3 patients with adenosine deaminase deficiency on long-term enzyme replacement therapy.|2020|Gans MD,Bernstein L,Shliozberg J,Gavrilova T,Rubinstein A,|

Urogenital Abnormalities in Adenosine Deaminase Deficiency.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7253380
Journal of Clinical Immunology; Pajno R, Pacillo L et. al.

Apr 20th, 2020 - Improved survival in ADA-SCID patients is revealing new aspects of the systemic disorder. Although increasing numbers of reports describe the systemic manifestations of adenosine deaminase deficiency, currently there are no studies in the literatu...

Adenosine deaminase deficiency: Treatment and prognosis
https://www.uptodate.com//contents/adenosine-deaminase-deficiency-treatment-and-prognosis
Eyal Grunebaum

INTRODUCTION Adenosine deaminase (ADA) deficiency (MIM #102700) is an autosomal recessive genetic disorder [ 1 ]. In approximately 90 percent of cases, it leads to a severe combined immunodeficiency (ADA-SCID) with dysfunction of T, B, and natural...

Adenosine deaminase deficiency: Pathogenesis, clinical manifestations, and diagnosis
https://www.uptodate.com//contents/adenosine-deaminase-deficiency-pathogenesis-clinical-manifestations-and-diagnosis
Eyal Grunebaum

INTRODUCTION Adenosine deaminase (ADA) deficiency (MIM #102700) was the first immunodeficiency in which the specific molecular defect was identified. This autosomal recessive genetic disorder typically leads to a severe combined immunodeficiency (...

see more →

Drugs  1 results see all →

Clinicaltrials.gov  91 results

Successful engraftment of haploidentical stem cell transplant with post-transplantation...
https://doi.org/10.1111/petr.13954
Pediatric Transplantation REFERENCES; Medina D, Aristizabal AM et. al.

Dec 29th, 2020 - SCID are characterized by an imbalance in cellular and humoral immunity. Enzyme ADA deficiency represents from 10% to 15% of the SCID. This generates diminished maturation of the cell precursors. Treatments include enzyme replacement therapy, allo...

Outcomes of 3 patients with adenosine deaminase deficiency on long-term enzyme replacem...
https://doi.org/10.1016/j.anai.2020.12.008
Annals of Allergy, Asthma & Immunology : Official Publica... Gans MD, Bernstein L et. al.

Dec 28th, 2020 - Outcomes of 3 patients with adenosine deaminase deficiency on long-term enzyme replacement therapy.|2020|Gans MD,Bernstein L,Shliozberg J,Gavrilova T,Rubinstein A,|

Urogenital Abnormalities in Adenosine Deaminase Deficiency.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7253380
Journal of Clinical Immunology; Pajno R, Pacillo L et. al.

Apr 20th, 2020 - Improved survival in ADA-SCID patients is revealing new aspects of the systemic disorder. Although increasing numbers of reports describe the systemic manifestations of adenosine deaminase deficiency, currently there are no studies in the literatu...

Adenosine deaminase deficiency: Treatment and prognosis
https://www.uptodate.com//contents/adenosine-deaminase-deficiency-treatment-and-prognosis
Eyal Grunebaum

INTRODUCTION Adenosine deaminase (ADA) deficiency (MIM #102700) is an autosomal recessive genetic disorder [ 1 ]. In approximately 90 percent of cases, it leads to a severe combined immunodeficiency (ADA-SCID) with dysfunction of T, B, and natural...

Adenosine deaminase deficiency: Pathogenesis, clinical manifestations, and diagnosis
https://www.uptodate.com//contents/adenosine-deaminase-deficiency-pathogenesis-clinical-manifestations-and-diagnosis
Eyal Grunebaum

INTRODUCTION Adenosine deaminase (ADA) deficiency (MIM #102700) was the first immunodeficiency in which the specific molecular defect was identified. This autosomal recessive genetic disorder typically leads to a severe combined immunodeficiency (...

see more →

News  1 results

EU Regulators Favor 'Bubble Boy' Gene Therapy (Strimvelis)
https://www.medscape.com/viewarticle/861416

Apr 3rd, 2016 - Editor’s note: The European Commission approved the gene therapy Strimvelis (GlaxoSmithKline) on May 27, 2016, to treat children with the very rare disease Severe Combined Immunodeficiency due to Adenosine Deaminase deficiency (ADA-SCID), accordin...

see more →