×
About 95 results

ALLMedicine™ Apparent Mineralocorticoid Excess Center

Research & Reviews  37 results

ERRATUM FOR: "Classic and Nonclassic Apparent Mineralocorticoid Excess Syndrome".
https://doi.org/10.1210/clinem/dgaa272
The Journal of Clinical Endocrinology and Metabolism;

Jan 14th, 2021 - ERRATUM FOR: "Classic and Nonclassic Apparent Mineralocorticoid Excess Syndrome".|2021||

Species-specific differences in the inhibition of 11β-hydroxysteroid dehydrogenase 2 by...
https://doi.org/10.1016/j.taap.2020.115387
Toxicology and Applied Pharmacology; Inderbinen SG, Zogg M et. al.

Jan 3rd, 2021 - 11β-hydroxysteroid dehydrogenase 2 (11β-HSD2) converts active 11β-hydroxyglucocorticoids to their inactive 11-keto forms, thereby preventing inappropriate mineralocorticoid receptor activation by glucocorticoids. Disruption of 11β-HSD2 activity by...

Apparent Mineralocorticoid Excess: Research as an Art Form.
https://doi.org/10.1007/s12020-020-02488-x
Endocrine Funder JW

Sep 30th, 2020 - Apparent Mineralocorticoid Excess: Research as an Art Form.|2020|Funder JW,|

Apparent mineralocorticoid excess caused by novel compound heterozygous mutations in HS...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7674368
Endocrine Fan P, Lu YT et. al.

Aug 21st, 2020 - Apparent mineralocorticoid excess (AME) is an ultrarare autosomal recessive disorder resulting from deficiency of 11β-hydroxysteroid dehydrogenase type 2 (11βHSD2) caused by mutations in HSD11B2. The purpose of this study was to identify novel com...

Classic and Nonclassic Apparent Mineralocorticoid Excess Syndrome.
https://doi.org/10.1210/clinem/dgz315
The Journal of Clinical Endocrinology and Metabolism; Carvajal CA, Tapia-Castillo A et. al.

Jan 8th, 2020 - Arterial hypertension (AHT) is one of the most frequent pathologies in the general population. Subtypes of essential hypertension characterized by low renin levels allowed the identification of 2 different clinical entities: aldosterone-mediated m...

see more →

Clinicaltrials.gov  1 results

Natural History of Apparent Mineralocorticoid Excess Syndrome
https://clinicaltrials.gov/ct2/show/NCT00474942

Dec 11th, 2015 - AME is a rare genetic disorder that is caused by a mutated HSD11B2 gene, which encodes the metabolic enzyme 11BHSD2. The altered gene interferes with the ability of 11BHSD2 to inactivate the hormone cortisol. Above-normal cortisol activity then le...

see more →