ALLMedicine™ Argininosuccinic Aciduria Center
Research & Reviews 12 results
Journal of Inherited Metabolic Disease REFERENCES; Brambilla A, Bianchi ML et. al.
May 6th, 2019 - No data are available on the specific energy needs of patients affected with Urea Cycle disorders (UCD) and especially argininosuccinic aciduria (ASA). In our experience, ASA patients tend to develop central adiposity and hypertriglyceridemia when...
Journal of Pediatric Gastroenterology and Nutrition; Porta F, Romagnoli R et. al.
Apr 10th, 2019 - Liver transplant (LT) is a therapeutic option for a growing number of inborn errors of metabolism (IEM), including some disorders not confined to the liver. Clinical advantages of LT in maple syrup urine disease (MSUD), methylmalonic acidemia (MMA...
Journal of Inherited Metabolic Disease; Baruteau J, Diez-Fernandez C et. al.
Feb 7th, 2019 - The first patients affected by argininosuccinic aciduria (ASA) were reported 60 years ago. The clinical presentation was initially described as similar to other urea cycle defects, but increasing evidence has shown overtime an atypical systemic ph...
Nature Communications; Baruteau J, Perocheau DP et. al.
Aug 31st, 2018 - Argininosuccinate lyase (ASL) belongs to the hepatic urea cycle detoxifying ammonia, and the citrulline-nitric oxide (NO) cycle producing NO. ASL-deficient patients present argininosuccinic aciduria characterised by hyperammonaemia, multiorgan dis...
Journal of Inherited Metabolic Disease; Baruteau J, Jameson E et. al.
Mar 3rd, 2017 - This UK-wide study defines the natural history of argininosuccinic aciduria and compares long-term neurological outcomes in patients presenting clinically or treated prospectively from birth with ammonia-lowering drugs. Retrospective analysis of m...
News 1 results
Apr 27th, 2012 - Action Points Nitric oxide supplements were able to rein in treatment-resistant hypertension in a patient with argininosuccinic aciduria (ASA), one of the most common urea-cycle disorders. Note that ASA is a congenital disorder that renders patien...