ALLMedicine™ Argininosuccinic Aciduria Center
Research & Reviews 33 results
https://clinicaltrials.gov/ct2/show/NCT03064048
Aug 19th, 2021 - Argininosuccinate lyase deficiency (ASLD; also known as argininosuccinic aciduria) is the second most common urea cycle disorder (UCD) and accounts for 15-20% of all disorders of ureagenesis. Individuals with ASLD can have unique clinical and phys...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9291867
Liver Transplantation : Official Publication of the Ameri... Ziogas IA, Wu WK et. al.
Jun 1st, 2021 - Liver transplantation (LT) for children with urea cycle disorders (UCDs) is capable of correcting the enzymatic defect and preventing progressive neurologic injury. We describe the characteristics and outcomes of pediatric LT recipients with UCDs....
https://clinicaltrials.gov/ct2/show/NCT02252770
Jan 18th, 2020 - The investigators will perform a double blind, randomized, placebo-controlled, crossover study of NO supplementation in ASA patients assessing endothelial function and blood pressure as primary endpoints, and markers of nitric oxide production as ...
https://doi.org/10.1002/jimd.12108
Journal of Inherited Metabolic Disease REFERENCES; Brambilla A, Bianchi ML et. al.
May 6th, 2019 - No data are available on the specific energy needs of patients affected with Urea Cycle disorders (UCD) and especially argininosuccinic aciduria (ASA). In our experience, ASA patients tend to develop central adiposity and hypertriglyceridemia when...
https://doi.org/10.1097/MPG.0000000000002354
Journal of Pediatric Gastroenterology and Nutrition; Porta F, Romagnoli R et. al.
Apr 10th, 2019 - Liver transplant (LT) is a therapeutic option for a growing number of inborn errors of metabolism (IEM), including some disorders not confined to the liver. Clinical advantages of LT in maple syrup urine disease (MSUD), methylmalonic acidemia (MMA...
Clinicaltrials.gov 4 results
https://clinicaltrials.gov/ct2/show/NCT03064048
Aug 19th, 2021 - Argininosuccinate lyase deficiency (ASLD; also known as argininosuccinic aciduria) is the second most common urea cycle disorder (UCD) and accounts for 15-20% of all disorders of ureagenesis. Individuals with ASLD can have unique clinical and phys...
https://clinicaltrials.gov/ct2/show/NCT02252770
Jan 18th, 2020 - The investigators will perform a double blind, randomized, placebo-controlled, crossover study of NO supplementation in ASA patients assessing endothelial function and blood pressure as primary endpoints, and markers of nitric oxide production as ...
https://clinicaltrials.gov/ct2/show/NCT00345605
Jan 31st, 2018 - The cause of liver damage in people with ASA is unknown. However, because ASA is the only urea cycle disorder that is characterized by both liver damage and elevated levels of argininosuccinic acid, researchers believe that the elevated acid level...
https://clinicaltrials.gov/ct2/show/NCT00004767
Jun 24th, 2005 - PROTOCOL OUTLINE: This protocol describes several clinical studies of pharmacologic and dietary management in patients with urea cycle disorders. Patients with carbamyl phosphate synthetase and ornithine transcarbamylase deficiency are treated wit...
News 2 results
https://www.mdedge.com/dermatology/article/97706/hair-nails/inability-grow-long-hair-presentation-trichorrhexis-nodosa
Teresa Sisto, MD, Carolina Bussoletti, MD et. al.
Mar 5th, 2015 - To the Editor: First identified by Samuel Wilks in 1852, trichorrhexis nodosa (TN) is a congenital or acquired hair shaft disorder that is characterized by fragile and easily broken hair. 1 Congenital TN is rare and can occur in syndromes such as p.
https://www.medpagetoday.com/cardiology/hypertension/32383
Apr 27th, 2012 - Action Points Nitric oxide supplements were able to rein in treatment-resistant hypertension in a patient with argininosuccinic aciduria (ASA), one of the most common urea-cycle disorders. Note that ASA is a congenital disorder that renders patien...