About 615 results

ALLMedicine™ Agammaglobulinemia Center

Research & Reviews  207 results

An X-linked agammaglobulinemia (XLA) patient with fever and disturbance of consciousnes...
International Journal of Infectious Diseases : IJID : Off... Liu H, Zhao J et. al.

Dec 6th, 2021 - This is the first report of meningoencephalitis in an adult male with X-linked agammaglobulinemia caused by a probable Torque teno virus (TTV) infection. TTV was detected in the cerebrospinal fluid samples of the patient by high-throughput sequenc...

Cost Utility of Lifelong Immunoglobulin Replacement Therapy vs Hematopoietic Stem Cell ...
JAMA Pediatrics; Sun D, Heimall JR et. al.

Nov 16th, 2021 - Lifelong immunoglobulin replacement therapy (IRT) is standard-of-care treatment for congenital agammaglobulinemia but accrues high annual costs ($30 000-$90 000 per year) and decrements to quality of life over patients' life spans. Hematopoietic s...

Treatment of chronic or relapsing COVID-19 in immunodeficiency.
The Journal of Allergy and Clinical Immunology; Brown LK, Moran E et. al.

Nov 16th, 2021 - Patients with some types of immunodeficiency can experience chronic or relapsing infection with severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2). This leads to morbidity and mortality, infection control challenges, and the risk of evol...

SARS-CoV-2 Vaccine Induced Atypical Immune Responses in Antibody Defects: Everybody Doe...
Journal of Clinical Immunology; Salinas AF, Mortari EP et. al.

Oct 21st, 2021 - Data on immune responses to SARS-CoV-2 in patients with Primary Antibody Deficiencies (PAD) are limited to infected patients and to heterogeneous cohorts after immunization. Forty-one patients with Common Variable Immune Deficiencies (CVID), six p...

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Drugs  21 results see all →

Clinicaltrials.gov  1 results

Study of Safety, Tolerability, and Efficacy of Ustekinumab for Symptomatic Gastrointestinal Inflammation Associated With Common Variable Immunodeficiency

Aug 24th, 2020 - The purpose of this study is to assess the safety/tolerability and efficacy of using ustekinumab in subjects with common variable immunodeficiency CVID or selective IgG subclass deficiency (functional agammaglobulinemia) who have associated sympto...

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News  13 results

Byrd Discusses Optimizing Ibrutinib and Idelalisib in CLL

Dec 20th, 2020 - John C. Byrd, MD In a presentation at the inaugural ASH Meeting on Hematologic Malignancies, John C. Byrd, MD, discussed what his clinical experience has revealed about the optimal use of ibrutinib (Imbruvica) and idelalisib (Zydelig) in chronic ...

The Changing Treatment Landscape in MCL and CLL: A Review of Standards of Care

Dec 5th, 2020 - Non-Hodgkin Lymphoma (NHL) is 1 of the 10 most common malignancies, accounting for approximately 3% to 4% of cancer cases worldwide.1 Over 30 different subtypes of NHL have been identified.2 Of these, B-cell lymphomas make up the majority of cases...

COVID-19 Outcomes Vary Widely in Patients With Primary Immunodeficiencies

Oct 20th, 2020 - NEW YORK (Reuters Health) - Clinical outcomes of COVID-19 in patients with primary immunodeficiency diseases range from mild illness to death, according to a small case series. "We were first surprised that we had only a few cases considering how ...

Dyspnea and Night Sweats in a 46-Year-Old Man

Jan 15th, 2020 - Which of the following is the most likely diagnosis? Your Peers Chose: Bruton agammaglobulinemia 0% Thymoma 0% Pheochromocytoma 0% Teratoma 0% Discussion The patient in this case was eventually diagnosed with thymoma. Symptoms from a thymoma or th...

IPD in children may be a signal of immunodeficiency
Bianca Nogrady

Oct 3rd, 2019 - Recurrent invasive pneumococcal disease in children could be a signal of underlying primary immunodeficiency, according to a systematic review published in JAMA Pediatrics. Coen Butters, BMed, DCH, of the Royal Children’s Hospital in Melbourne, an.

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Patient Education  4 results see all →