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ALLMedicine™ Agammaglobulinemia Center

Research & Reviews  183 results

Primary hypogammaglobulinemia with IBD-like features: An ECCO CONFER Multicenter Case S...
https://doi.org/10.1093/ecco-jcc/jjab124
Journal of Crohn's & Colitis; Albshesh A, Eder P et. al.

Jul 19th, 2021 - Hypogammaglobulinemia is a disorder characterized by low serum immunoglobulin levels and had high prevalence of gastrointestinal manifestations. In some cases, clinical and endoscopic features are indistinguishable from those of inflammatory bowel...

Common Variable Immunodeficiency and Other Immunodeficiency Syndromes in Bronchiectasis.
https://doi.org/10.1055/s-0041-1730893
Seminars in Respiratory and Critical Care Medicine; McShane PJ

Jul 15th, 2021 - Immunodeficiency represents a vast number of diseases and syndromes. Both primary and secondary forms of immunodeficiency are important contributors to the development of bronchiectasis. Primary immune deficiencies, in particular, are increasingly...

Whole genome sequencing identifies novel structural variant in a large Indian family af...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8274882
PloS One; Jain A, Govindaraj GM et. al.

Jul 13th, 2021 - X-linked agammaglobulinemia (XLA, OMIM #300755) is a primary immunodeficiency disorder caused by pathogenic variations in the BTK gene, characterized by failure of development and maturation of B lymphocytes. The estimated prevalence worldwide is ...

Agammaglobulinemia: from X-linked to Autosomal Forms of Disease.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8269404
Clinical Reviews in Allergy & Immunology; Cardenas-Morales M, Hernandez-Trujillo VP

Jul 10th, 2021 - Interruptions or alterations in the B cell development pathway can lead to primary B cell immunodeficiency with resultant absence or diminished immunoglobulin production. While the most common cause of congenital agammaglobulinemia is X-linked aga...

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Drugs  21 results see all →

News  10 results

COVID-19 Outcomes Vary Widely in Patients With Primary Immunodeficiencies
https://www.staging.medscape.com/viewarticle/939374

Oct 20th, 2020 - NEW YORK (Reuters Health) - Clinical outcomes of COVID-19 in patients with primary immunodeficiency diseases range from mild illness to death, according to a small case series. "We were first surprised that we had only a few cases considering how ...

Dyspnea and Night Sweats in a 46-Year-Old Man
https://reference.medscape.com/viewarticle/732961_3

Jan 15th, 2020 - Which of the following is the most likely diagnosis? Your Peers Chose: Bruton agammaglobulinemia 0% Thymoma 0% Pheochromocytoma 0% Teratoma 0% Discussion The patient in this case was eventually diagnosed with thymoma. Symptoms from a thymoma or th...

IPD in children may be a signal of immunodeficiency
https://www.mdedge.com/clinicianreviews/article/209354/infectious-diseases/ipd-children-may-be-signal-immunodeficiency?channel=284
Bianca Nogrady

Oct 3rd, 2019 - Recurrent invasive pneumococcal disease in children could be a signal of underlying primary immunodeficiency, according to a systematic review published in JAMA Pediatrics. Coen Butters, BMed, DCH, of the Royal Children’s Hospital in Melbourne, an.

FDA OKs Immunoglobulin Xembify for Primary Immunodeficiencies
https://www.medscape.com/viewarticle/915280

Jul 5th, 2019 - The US Food and Drug Administration (FDA) has approved a 20% immune globulin solution for subcutaneous injection (Xembify, Grifols) to treat primary immunodeficiencies in patients as young as 2 years old, according to a company statement. The appr...

FDA approves IVIG product for PI and chronic ITP
https://www.mdedge.com/hematology-oncology/article/186860/anemia/fda-approves-ivig-product-pi-and-chronic-itp
HT Staff

Feb 9th, 2017 - Vials of product Photo by Bill Branson The US Food and Drug Administration (FDA) has approved an intravenous immunoglobulin (IVIG) product (Gammaplex® 10%) for the treatment of primary immunodeficiency (PI) and chronic immune thrombocytopenia (ITP.

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