ALLMedicine™ Atypical Werner Syndrome Center
Research & Reviews 8 results
Journal of Clinical Rheumatology : Practical Reports on R... Suárez-Díaz S, Castaño-Álvarez J et. al.
Jul 23rd, 2020 - Atypical Werner Syndrome: Another Scleroderma-Like Fibrosing Disorder.|2020|Suárez-Díaz S,Castaño-Álvarez J,Noval-Tuñón I,Coto-Hernández R,Caminal-Montero L,|
Endocrine Journal; He G, Yan Z et. al.
Jul 5th, 2019 - Werner syndrome (WS) is a rare, adult-onset progeroid syndrome. Classic WS is caused by WRN mutation and partial atypical WS (AWS) is caused by LMNA mutation. A 19-year-old female patient with irregular menstruation and hyperglycemia was admitted....
Gene Nicolas E, Golemis EA et. al.
Jun 21st, 2016 - The evolutionarily conserved human polymerase delta (POLD1) gene encodes the large p125 subunit which provides the essential catalytic activities of polymerase δ (Polδ), mediated by 5'-3' DNA polymerase and 3'-5' exonuclease moieties. POLD1 associ...
The Journal of Investigative Dermatology; McKenna T, Sola Carvajal A et. al.
Aug 21st, 2015 - The nuclear lamina, a protein network located under the nuclear membrane, has during the past decade found increasing interest due to its significant involvement in a range of genetic diseases, including the segmental premature aging syndromes Hut...
Gerontology Oshima J, Hisama FM
Jan 10th, 2014 - Segmental progeroid syndromes are a group of disorders with multiple features resembling accelerated aging. Adult-onset Werner syndrome (WS) and childhood-onset Hutchinson-Gilford progeria syndrome are the best known examples. The discovery of gen...