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ALLMedicine™ Atypical Werner Syndrome Center

Research & Reviews  8 results

Atypical Werner Syndrome: Another Scleroderma-Like Fibrosing Disorder.
Journal of Clinical Rheumatology : Practical Reports on R... Suárez-Díaz S, Castaño-Álvarez J et. al.

Jul 23rd, 2020 - Atypical Werner Syndrome: Another Scleroderma-Like Fibrosing Disorder.|2020|Suárez-Díaz S,Castaño-Álvarez J,Noval-Tuñón I,Coto-Hernández R,Caminal-Montero L,|

Diabetes mellitus coexisted with progeria: a case report of atypical Werner syndrome wi...
Endocrine Journal; He G, Yan Z et. al.

Jul 5th, 2019 - Werner syndrome (WS) is a rare, adult-onset progeroid syndrome. Classic WS is caused by WRN mutation and partial atypical WS (AWS) is caused by LMNA mutation. A 19-year-old female patient with irregular menstruation and hyperglycemia was admitted....

POLD1: Central mediator of DNA replication and repair, and implication in cancer and ot...
Gene Nicolas E, Golemis EA et. al.

Jun 21st, 2016 - The evolutionarily conserved human polymerase delta (POLD1) gene encodes the large p125 subunit which provides the essential catalytic activities of polymerase δ (Polδ), mediated by 5'-3' DNA polymerase and 3'-5' exonuclease moieties. POLD1 associ...

Skin Disease in Laminopathy-Associated Premature Aging.
The Journal of Investigative Dermatology; McKenna T, Sola Carvajal A et. al.

Aug 21st, 2015 - The nuclear lamina, a protein network located under the nuclear membrane, has during the past decade found increasing interest due to its significant involvement in a range of genetic diseases, including the segmental premature aging syndromes Hut...

Search and insights into novel genetic alterations leading to classical and atypical We...
Gerontology Oshima J, Hisama FM

Jan 10th, 2014 - Segmental progeroid syndromes are a group of disorders with multiple features resembling accelerated aging. Adult-onset Werner syndrome (WS) and childhood-onset Hutchinson-Gilford progeria syndrome are the best known examples. The discovery of gen...

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