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About 720 results

ALLMedicine™ Beckwith-Wiedemann Syndrome Center

Research & Reviews  284 results

Spontaneous and ART-induced large offspring syndrome: similarities and differences in D...
https://doi.org/10.1080/15592294.2022.2067938
Epigenetics Li Y, Sena Lopes J et. al.

Apr 26th, 2022 - Large/abnormal offspring syndrome (LOS/AOS) is a congenital overgrowth syndrome reported in ruminants produced by assisted reproduction (ART-LOS) which exhibit global disruption of the epigenome and transcriptome. LOS/AOS shares phenotypes and epi...

Multi-locus DNA methylation analysis of imprinted genes in cattle from somatic cell nuc...
https://doi.org/10.1016/j.theriogenology.2022.04.006
Theriogenology Mangiavacchi PM, Caldas-Bussiere MC et. al.

Apr 20th, 2022 - Multi-locus methylation defects (MLMDs) in imprinted loci have been reported in Beckwith-Wiedemann Syndrome (BWS). Large offspring syndrome (LOS), a phenotypic subgroup of abnormal offspring syndrome (AOS), is considered a molecular and phenotypic...

Novel multilocus imprinting disturbances in a child with expressive language delay and ...
https://doi.org/10.1002/ajmg.a.62752
American Journal of Medical Genetics. Part A; Tayeh MK, DeVaul J et. al.

Apr 3rd, 2022 - Multilocus imprinting disturbances (MLID) have been associated with up to 12% of patients with Beckwith-Wiedemann syndrome, Silver-Russell syndrome, and pseudohypoparathyroidism type 1B (PHP1B). Single-gene defects affecting components of the subc...

Adrenal cytomegaly with elevated serum androgen levels in a patient with Beckwith-Wiede...
https://doi.org/10.1507/endocrj.EJ21-0261
Endocrine Journal; Aoki M, Uehara S et. al.

Mar 25th, 2022 - Beckwith-Wiedemann syndrome (BWS) is infrequently associated with adrenocortical carcinoma (ACC) or non-hormone-producing adrenal cytomegaly, but we recently, encountered a single case of adrenal cytomegaly in a patient with BWS, which was difficu...

Combination Chemotherapy and Surgery in Treating Young Patients With Wilms Tumor
https://clinicaltrials.gov/ct2/show/NCT00945009

Mar 25th, 2022 - OBJECTIVES: I. To improve 4-year event-free survival (EFS) to 73% for young patients with bilateral Wilms tumor (BWT). II. To prevent complete removal of at least one kidney in 50% of patients with BWT by using prenephrectomy 3-drug chemotherapy i...

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Clinicaltrials.gov  2 results

Combination Chemotherapy and Surgery in Treating Young Patients With Wilms Tumor
https://clinicaltrials.gov/ct2/show/NCT00945009

Mar 25th, 2022 - OBJECTIVES: I. To improve 4-year event-free survival (EFS) to 73% for young patients with bilateral Wilms tumor (BWT). II. To prevent complete removal of at least one kidney in 50% of patients with BWT by using prenephrectomy 3-drug chemotherapy i...

Body Perception and Representation in Overgrowth Syndromes, Behavioral Assessment and Neuropsychological Development
https://clinicaltrials.gov/ct2/show/NCT04993235

Aug 6th, 2021 - Background and Rationale Sotos Syndrome (SS) and Beckwith-Wiedemann Syndrome (BWS) are known as overgrowth syndromes as they involve alterations in dimensions of the whole body or of specific body parts. SS is characterized by advanced bone age, m...

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News  2 results

Preliminary analysis confirms birth defect-cancer association
https://www.mdedge.com/pediatrics/article/98883/pediatrics/preliminary-analysis-confirms-birth-defect-cancer-association
Sharon Worcester

Apr 18th, 2015 - BIRMINGHAM, ALA. – Children with birth defects have been shown to have an increased risk of developing cancer, and preliminary findings from a large record-linkage study not only confirm and better define the risk, but also demonstrate the value o.

Assisted Reproduction Linked to Rare Genetic Disorder
https://www.medscape.com/viewarticle/448031

Jan 15th, 2003 - Jan. 15, 2003 -- Preliminary findings from two recent studies indicate that the process of assisted reproduction can cause the genetic disruption associated with the disorder Beckwith-Wiedemann syndrome (BWS). New research from the U.K., published...

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